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Novel immunotherapy eradicates solid tumors in mice without adverse side effects

Scientists have developed a new immunotherapy that eradicates solid tumors in mice without adverse side effects, according to a new study published today in eLife.

31 Mar 2020

Investigational oral form of treatment offers hope for adults with acromegaly

Adults who need medical maintenance treatment of the growth hormone disorder acromegaly respond well to an investigational oral form of the drug octreotide, investigators of the Chiasma OPTIMAL study reported.

31 Mar 2020

Study finds high rates of depression, suicidal thoughts among transgender teens

Two-thirds of transgender teens have depression, and many also have suicidal thoughts and self-injuring behavior, according to research accepted for presentation at ENDO 2020, the Endocrine Society's annual meeting, and publication in a special supplemental section of the Journal of the Endocrine Society.

31 Mar 2020

Thyroid hormone replacement therapy linked to higher risk of death in older adults

Thyroid hormone replacement therapy in older adults is associated with a higher risk of death compared with no treatment, a large study finds.

31 Mar 2020

Exercising women with menstrual disorders can avoid complications by consuming extra calories

Exercising women who struggle to consume enough calories and have menstrual disorders can simply increase their food intake to recover their menstrual cycle, according to a study accepted for presentation at ENDO 2020, the Endocrine Society's annual meeting, and publication in the Journal of the Endocrine Society.

31 Mar 2020

Cobra Biologics and Karolinska Institutet join forces to develop DNA vaccine against COVID-19

Cobra Biologics, an international CDMO for biologics and pharmaceuticals, and the Karolinska Institutet, one of the world’s leading medical universities, today announced they have been awarded €3 million emergency funding by Horizon 2020 for research and development, and phase I clinical trial testing of a DNA vaccine against COVID-19, as part of the OPENCORONA consortium to support global efforts tackling the pandemic.

31 Mar 2020

Potential new method of breast cancer treatment using androgen receptor

Scientists may have discovered a new therapeutic approach to treat ER+ breast cancer using androgen receptor-stimulating drugs.

31 Mar 2020

Online coronavirus tests are just the latest iffy products marketed to anxious consumers

Companies with experience in the "at-home" testing market began announcing in mid-March that they would be offering direct-to-consumer test kits for COVID-19.

31 Mar 2020

Should you bring mom home from assisted living during the pandemic?

Dr. Alison Webb took her 81-year-old father out of assisted living, to live.

31 Mar 2020

Fee app helps track onset and progression of COVID-19 symptoms in Americans

As the COVID-19 coronavirus pandemic grips the US, a new free app is helping to track the onset and progression of symptoms of millions across the nation. The app will help identify those at risk sooner, and help slow the outbreak of the disease.

31 Mar 2020

Evinacumab drug reduces cholesterol levels in patients with rare cholesterol disorder

The investigational drug evinacumab reduced low-density lipoprotein (LDL) cholesterol to near-normal levels among patients with a rare cholesterol disorder, meeting the primary endpoint in the first randomized placebo-controlled trial of the drug, which is being presented at the American College of Cardiology's Annual Scientific Session Together with World Congress of Cardiology (ACC.20/WCC).

31 Mar 2020

Ticagrelor therapy, without aspirin, can benefit patients with acute coronary syndrome

Patients with acute coronary syndrome (ACS) who stopped taking aspirin three months after the insertion of a coronary stent and then took the anti-platelet medication ticagrelor alone for nine months had fewer episodes of bleeding and no increase in heart attacks, stroke or other adverse events caused by blockages in the arteries, compared with patients who took both aspirin and ticagrelor for a year.

31 Mar 2020

Why do men stop treatment for erectile dysfunction?

A new study published in the journal IJIR: Your Sexual Medicine Journal in March 2020 reports the most common reasons why men stop their treatment for erectile dysfunction. The most common reasons were that the treatment did not work, cost too much, or had unacceptable side effects. Loss of interest in sexual relationships was another primary reason.

31 Mar 2020

Clopidogrel added to aspirin and rvaroxaban shows no additional benefit for peripheral artery disease

The results of VOYAGER PAD found that people with peripheral artery disease (PAD) who took the blood thinner rivaroxaban with aspirin after undergoing lower extremity revascularization--a procedure to treat blocked arteries in the leg--had a significant reduction in the risk of major adverse limb and cardiovascular events when compared with those receiving aspirin alone.

31 Mar 2020

New study helps identify drugs that are safe for treating COVID-19

A recent study has found that there is no evidence for or against the use of non-steroidal anti-inflammatory drugs such as ibuprofen for patients with COVID-19.

31 Mar 2020

Vaping with counseling more effective than counseling alone for smoking cessation

Smokers who received smoking cessation counseling and used electronic cigarettes containing nicotine were more than twice as likely to successfully quit smoking compared to those who received counseling but did not use e-cigarettes, in a clinical trial presented at the American College of Cardiology's Annual Scientific Session Together with World Congress of Cardiology.

30 Mar 2020

Higher serum EPA levels from prescription fish oil associated with lower cardiovascular events

Higher levels of the omega-3 fatty acid eicosapentaenoic acid (EPA) found in the blood—and not a decrease in triglyceride levels as originally thought—appear to explain the striking reductions in cardiovascular events and deaths seen among people taking 4 grams daily of the prescription fish oil, icosapent ethyl, according to findings from a REDUCE-IT substudy presented at the American College of Cardiology's Annual Scientific Session Together with World Congress of Cardiology

30 Mar 2020

Temple researchers reverse muscle fibrosis associated with overuse injury in animals

Overuse injuries - think muscle strains, tennis elbow, and rotator cuff tears - are a considerable problem in the United States, especially among young athletes.

30 Mar 2020

Clinical trial using genetic testing to guide antiplatelet therapy post-PCI falls short of stated goal

An international clinical trial that used genetic testing to guide which antiplatelet medication was given to patients following percutaneous coronary intervention (PCI) did not meet its stated goal for cutting in half the incidence of serious adverse cardiovascular events, such as heart attack and stroke, in the year following the procedure.

30 Mar 2020

UVA researchers find way to enhance cancer outcomes by examining patients' genetic data

By mining a vast trove of genetic data, researchers at the University of Virginia School of Medicine are enhancing doctors’ ability to treat cancer, predict patient outcomes and determine which treatments will work best for individual patients.

30 Mar 2020

Therapy News and Research

Novel immunotherapy eradicates solid tumors in mice without adverse side effects

Investigational oral form of treatment offers hope for adults with acromegaly

Study finds high rates of depression, suicidal thoughts among transgender teens

Thyroid hormone replacement therapy linked to higher risk of death in older adults

Exercising women with menstrual disorders can avoid complications by consuming extra calories

Cobra Biologics and Karolinska Institutet join forces to develop DNA vaccine against COVID-19

Potential new method of breast cancer treatment using androgen receptor

Online coronavirus tests are just the latest iffy products marketed to anxious consumers

Should you bring mom home from assisted living during the pandemic?

Fee app helps track onset and progression of COVID-19 symptoms in Americans

Evinacumab drug reduces cholesterol levels in patients with rare cholesterol disorder

Ticagrelor therapy, without aspirin, can benefit patients with acute coronary syndrome

Why do men stop treatment for erectile dysfunction?

Clopidogrel added to aspirin and rvaroxaban shows no additional benefit for peripheral artery disease

New study helps identify drugs that are safe for treating COVID-19

Vaping with counseling more effective than counseling alone for smoking cessation

Higher serum EPA levels from prescription fish oil associated with lower cardiovascular events

Temple researchers reverse muscle fibrosis associated with overuse injury in animals

Clinical trial using genetic testing to guide antiplatelet therapy post-PCI falls short of stated goal

UVA researchers find way to enhance cancer outcomes by examining patients' genetic data

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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