Cellular Biology News and Research

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Pesticides more influential in causing cancer than previously thought

New research at the University of Liverpool suggests that environmental contaminants, such as pesticides, are more influential in causing cancer than previously thought.

20 Mar 2006

Scientists have gained valuable new insight into the biology of aggressive, incurable brain tumors

A research study published in the March issue of Cancer Cell uses gene expression profiling to identify molecular profiles and signaling pathways associated with tumor aggressiveness and disease progression.

15 Mar 2006

Smk-1 is the first known gene that regulates longevity without disrupting life-sustaining function

Within a hormone-triggered cascade of molecular signals that plays a crucial for a wide range of physiological functions, researchers for the very first time have identified a protein that functions specifically to extend lifespan and youthfulness - without disrupting fertility

13 Mar 2006

Genetic switch that turns off an oxygen-poor cell's combustion engine - finding has potential to limit toxic molecules

Johns Hopkins researchers have discovered a previously unrecognized role played by the gene HIF-1 as it helps cell survive when a lack of oxygen decreases production of an energy-rich molecule called ATP and increases production of toxic molecules.

9 Mar 2006

Study may lead to ways to reduce heart attacks in diabetes patients

For people with type 2 diabetes, the death rate from a first heart attack is two to three times the death rate of patients without the disease. Similarly, patients with diabetes and ischemic (reduced blood flow) heart disease have a much higher mortality rate than the general population.

7 Mar 2006

Factor B and H genes found to play role in the development of age-related macular degeneration

A new study, led by researchers at Columbia University Medical Center, pinpoints the role that two genes - Factor H and Factor B - play in the development of nearly three out of four cases of age-related macular degeneration (AMD), a devastating eye disease that affects more than 10 million people in the United States.

7 Mar 2006

Fibulins inhibit both tumor growth and blood-vessel formation

Researchers at National Jewish Medical and Research Center report in the March issue of Cancer Research that a pair of promising proteins, known as fibulins 3 and 5, slow the growth of cancer tumors in mice by preventing blood vessels from sprouting. The proteins are promising candidates for use in cancer therapy.

1 Mar 2006

New generation gold-based drugs for treating rheumatoid arthritis

Gold compounds have been used for the treatment of rheumatoid arthritis and other autoimmune diseases for more than 75 years, but until now, how the metals work has been a mystery.

27 Feb 2006

New mechanism that regulates K-Ras - protein that plays an important role in cancer

Researchers have discovered a protein widely known to cause the out-of-control growth of cells can actually be manipulated to induce those cells to commit suicide, providing a novel target for the development of anti-cancer drugs, according to the results of a new study led by New York University School of Medicine researchers.

21 Feb 2006

Inactivating Rad9 protien could make cancer cells easier to kill with ionizing radiation

The researchers found that Rad9, previously considered a "watchman" that checks for DNA damage, is actually a "repairman" that fixes dangerous breaks in the DNA double helix. They found Rad9 is especially active in telomeres, the protective ends of chromosomes.

17 Feb 2006

Scientists map brain area that may help find human brain stem cells

A study led by a Johns Hopkins neurosurgeon has provided the first comprehensive map of a part of the adult human brain containing astrocytes, cells known to produce growth factors critical to the regeneration of damaged neural tissue and that potentially serve as brain stem cells.

17 Feb 2006

Genome data may contain small but significant errors

Since the genome sequence of the bacterial pathogen Haemophilus influenzae was published in 1995, the genetic code of many other large, complex, medically, and commercially significant organisms including humans has also been elucidated

17 Feb 2006

Research suggests that a common mechanism may underlie a variety of protein folding diseases

Misfolded and damaged proteins are common to all human neurodegenerative diseases. Clumps of these aggregated proteins destroy neurons within the brain and cause disease.

16 Feb 2006

Macrophage signaling may affect hormone resistance in prostate tumors

Interaction between prostate cancer cells and immune cells called macrophages may be a source of inflammatory signals capable of impacting the effectiveness of androgen antagonists, the most common and effective treatment for prostate cancer, according to a new study by researchers at the University of California, San Diego (UCSD) School of Medicine.

16 Feb 2006

Broccoli, cauliflower and cabbage help repair damaged DNA

Need another reason to eat your vegetables? New research shows that some of them contain chemicals that appear to enhance DNA repair in cells, which could lead to protection against cancer development, say Georgetown University Medical Center researchers.

14 Feb 2006

Molecular Devices introduces a high-speed, laser-scanning, confocal imager

This system is the latest addition to its Total Imaging Solution which includes the ImageXpressMICRO imaging system, MetaXpress Software Application Modules, AcuityXpress Data Analysis software and the Transfluor Assay for GPCRs.

7 Feb 2006

Hormone discovered in bird brains also plays major role in mammalian reproductive system

University of California, Berkeley, researchers have discovered a new actor in the mammalian reproductive system, a hormone that fills a role long suspected, but until now undetected.

7 Feb 2006

Mad cow proteins also maintain stem cells

What do mad cow disease and stem cell research have in common? Whitehead Institute scientists have found that the same protein that causes neurodegenerative conditions such as bovine spongiform encephalopathy (mad cow disease) is also important for helping certain adult stem cells maintain themselves.

7 Feb 2006

DNA end caps may lead to cancer treatments

The two ends of human DNA have different structures that are treated differently as a cell divides, UT Southwestern Medical Center researchers have found in a study that could help lead to cancer therapies.

7 Feb 2006

BRCA1 gene inhibits estrogen and progesterone

It's been known that the breast cancer susceptibility gene BRCA1 regulates use of estrogen in breast and other cells, but now researchers at Georgetown University Medical Center have discovered that it also controls activity of a second sex steroid hormone, progesterone.

27 Jan 2006

Cellular Biology News and Research

Pesticides more influential in causing cancer than previously thought

Scientists have gained valuable new insight into the biology of aggressive, incurable brain tumors

Smk-1 is the first known gene that regulates longevity without disrupting life-sustaining function

Genetic switch that turns off an oxygen-poor cell's combustion engine - finding has potential to limit toxic molecules

Study may lead to ways to reduce heart attacks in diabetes patients

Factor B and H genes found to play role in the development of age-related macular degeneration

Fibulins inhibit both tumor growth and blood-vessel formation

New generation gold-based drugs for treating rheumatoid arthritis

New mechanism that regulates K-Ras - protein that plays an important role in cancer

Inactivating Rad9 protien could make cancer cells easier to kill with ionizing radiation

Scientists map brain area that may help find human brain stem cells

Genome data may contain small but significant errors

Research suggests that a common mechanism may underlie a variety of protein folding diseases

Macrophage signaling may affect hormone resistance in prostate tumors

Broccoli, cauliflower and cabbage help repair damaged DNA

Molecular Devices introduces a high-speed, laser-scanning, confocal imager

Hormone discovered in bird brains also plays major role in mammalian reproductive system

Mad cow proteins also maintain stem cells

DNA end caps may lead to cancer treatments

BRCA1 gene inhibits estrogen and progesterone

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