Cholesterol News and Research

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Cholesterol is a waxy, fat-like substance made in the liver, and found in the blood and in all cells of the body. Cholesterol is important for good health and is needed for making cell walls, tissues, hormones, vitamin D, and bile acid.

Exploring the intersection: Cardiovascular mortality trends among Alzheimer’s patients in the U.S.

Researchers compare the trends in cardiovascular disease-related mortality among patients with Alzheimer’s disease with general United States population.

23 Nov 2023

Reducing cholesterol esters protects the brain against Alzheimer's-like damage

In Alzheimer's disease and related dementias, cognitive decline is driven by the overaccumulation of a normal brain protein known as tau.

22 Nov 2023

Pulses found to significantly improve the nutritional profile of American diet

A recently published study in Nutrients, an open-access peer-reviewed scientific journal, demonstrates that exchanging pulses for small amounts of typical protein sources and refined grains significantly improves the nutritional profile of the American diet.

22 Nov 2023

Statins may reduce breast cancer mortality rates

The relationship between serological cholesterol levels, statin usage, and breast cancer (BC) mortality.

21 Nov 2023

New study links DNA methylation in GLP1R gene to obesity without metabolic disorders

The study investigates the role of epigenetic changes in GLP1R gene polymorphisms on metabolically healthy obesity (MHO), revealing that apart from genetic variations, DNA methylation significantly influences the occurrence of MHO.

20 Nov 2023

Young people may be more susceptible to the effects of elevated blood cholesterol and hypertension

Young people may be more susceptible to the effects of the risk factors for developing atherosclerosis. According to a study carried out at the Centro Nacional de Investigaciones Cardiovasculares (CNIC), younger people are especially vulnerable to the damaging effects of elevated blood cholesterol and hypertension, two of the major modifiable cardiovascular risk factors.

20 Nov 2023

Academic medical centers may help mitigate structural racism in cardiovascular care for Black women

Investigators from the Barbra Streisand Women’s Heart Center in the Smidt Heart Institute at Cedars-Sinai have found that among a cohort of women with obstructive coronary artery disease treated at academic medical centers, racial and ethnic disparities did not impact their long-term outcomes.

20 Nov 2023

High cholesterol in midlife linked to later-life dementia

An increasing number of studies have found a significant link between higher cholesterol levels in midlife and Alzheimer's disease and dementia in later life. Swap fatty foods for healthier options this Christmas and get tested now, says a leading testing expert.

20 Nov 2023

UK's national health service diabetes program proves effective in managing prediabetes, major study finds

Researchers examined the original framework of the NHS Diabetes Prevention Programme (DPP) implemented in the UK.

19 Nov 2023

Norwegian study looks at which medicines best prevent migraine

Migraine is more than just a headache. Often the pain is accompanied by nausea, vomiting, light sensitivity, and sound sensitivity.

17 Nov 2023

Unraveling the immune system's response to nanoparticle drug delivery

To reduce the side effects associated with chemotherapy treatments, researchers have investigated the use of delivery systems that can take more drugs directly to the tumor. Ninh (Irene) La-Beck, Pharm.D., from the Department of Immunotherapeutics and Biotechnology at the Texas Tech University Health Sciences Center (TTUHSC) Jerry H. Hodge School of Pharmacy is one of those researchers.

17 Nov 2023

Microglia found to play crucial role in early human brain development

An international team of scientists has uncovered the vital role of microglia, the immune cells in the brain that acts as its dedicated defense team, in early human brain development.

14 Nov 2023

Automated referrals to pharmacy services dramatically increase appropriate statin prescription rates

The odds of prescribing the appropriate dose of statins - a medicine used to lower "bad" cholesterol levels - increased sixfold when automated referrals were made to pharmacy services, instead of relying on traditional prescribing methods, according to researchers at the Perelman School of Medicine at the University of Pennsylvania.

13 Nov 2023

"Christchurch mutation" can block detrimental effects of Alzheimer’s risk factor

Researchers at Gladstone Institutes have discovered that a rare genetic variant known as the "Christchurch mutation" can block detrimental effects of apolipoprotein E4, the best-established risk factor for the most common form of Alzheimer's disease.

13 Nov 2023

Optimal hydration post-exercise: Study compares sodium and carbohydrate levels in sports drinks for effective rehydration

In this study, researchers compared the effectiveness of sports drinks with varying carbohydrate and sodium levels for rehydrating athletes post-exercise, finding that drinks with higher sodium and lower carbohydrate content were more effective for rapid and complete rehydration. The study highlighted the importance of beverage composition in athlete recovery and hydration strategies.

13 Nov 2023

Recaticimab injection every 1-3 months may safely lower bad cholesterol

A new PCSK9 inhibitor (recaticimab) injected every one to three months may work safely and provide more flexible dosing to lower cholesterol, according to late-breaking science presented today at the American Heart Association's Scientific Sessions 2023.

13 Nov 2023

Single injection of new medication effectively eliminates Lp(a) for nearly one year

In the first human trial of a new therapeutic, a single injection of lepodisiran reduced levels of lipoprotein(a), or Lp(a), to undetectable levels for nearly one year, according to late-breaking science presented today at the American Heart Association's Scientific Sessions 2023.

13 Nov 2023

CRISPR-based gene-editing therapy could offer hope for people with inherited high LDL cholesterol

A single infusion of a CRISPR-based gene-editing therapy significantly reduced low-density lipoprotein cholesterol (LDL, the "bad cholesterol") in people who carry one gene for the inherited condition that results in very high LDL cholesterol levels and a high risk of heart attack at an early age, according to late-breaking science presented today at the American Heart Association's Scientific Sessions 2023.

13 Nov 2023

SELECT trial: Semaglutide reduces cardiovascular events by 20% in overweight or obese patients without diabetes

Findings from a multi-center, international clinical trial reported by a Cleveland Clinic physician show that semaglutide reduced cardiovascular events by 20% in adults with overweight or obesity and established cardiovascular disease who do not have diabetes.

13 Nov 2023

UK regulator approves a diabetes drug for weight management in obese and overweight patients

The Medicines and Healthcare products Regulatory Agency (MHRA) has today (8 November 2023) authorised via a national application route, a new indication for the diabetes medicine, Mounjaro (tirzepatide), for weight loss and weight management in adults aged 18 and over.

13 Nov 2023

Cholesterol News and Research

Further Reading

Exploring the intersection: Cardiovascular mortality trends among Alzheimer’s patients in the U.S.

Reducing cholesterol esters protects the brain against Alzheimer's-like damage

Pulses found to significantly improve the nutritional profile of American diet

Statins may reduce breast cancer mortality rates

New study links DNA methylation in GLP1R gene to obesity without metabolic disorders

Young people may be more susceptible to the effects of elevated blood cholesterol and hypertension

Academic medical centers may help mitigate structural racism in cardiovascular care for Black women

High cholesterol in midlife linked to later-life dementia

UK's national health service diabetes program proves effective in managing prediabetes, major study finds

Norwegian study looks at which medicines best prevent migraine

Unraveling the immune system's response to nanoparticle drug delivery

Microglia found to play crucial role in early human brain development

Automated referrals to pharmacy services dramatically increase appropriate statin prescription rates

"Christchurch mutation" can block detrimental effects of Alzheimer’s risk factor

Optimal hydration post-exercise: Study compares sodium and carbohydrate levels in sports drinks for effective rehydration

Recaticimab injection every 1-3 months may safely lower bad cholesterol

Single injection of new medication effectively eliminates Lp(a) for nearly one year

CRISPR-based gene-editing therapy could offer hope for people with inherited high LDL cholesterol

SELECT trial: Semaglutide reduces cardiovascular events by 20% in overweight or obese patients without diabetes

UK regulator approves a diabetes drug for weight management in obese and overweight patients

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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