Hematology News and Research

RSS

Hematology, also spelled haematology, is the branch of biology (physiology), pathology, clinical laboratory, internal medicine, and pediatrics that is concerned with the study of blood, the blood-forming organs, and blood diseases. Hematology includes the study of etiology, diagnosis, treatment, prognosis, and prevention of blood diseases.

Leukaemia patients could safely reduce side effects of drug by cutting dose in half, study shows

Patients with a chronic type of leukaemia could safely reduce the side effects of life-long treatment by cutting their dose in half, according to the results of a University of Liverpool led study presented at an international conference in America this week.

6 Dec 2016

Researchers unveil new role of thymic dendritic cells in controlling T lymphocyte egress into the blood

A team of scientists led by Julie Saba, MD, PhD at UCSF Benioff Children's Hospital Oakland, has unveiled a novel role of thymic dendritic cells, which could result in new strategies to treat conditions such as autoimmune diseases, immune deficiencies, prematurity, infections, cancer, and the loss of immunity after bone marrow transplantation.

6 Dec 2016

Additions to standard therapy do not improve progression-free survival in patients with multiple myeloma

Trial results being presented today during the 58th American Society of Hematology Annual Meeting and Exposition in San Diego suggest two therapies that are often added to standard therapy in patients with multiple myeloma do not improve rates of progression-free survival compared with the current standard course of treatment alone.

6 Dec 2016

Research findings point to inherited genetic basis of ALL risk in children

A late-breaking abstract being presented today during the 58th American Society of Hematology Annual Meeting and Exposition in San Diego identifies inherited genetic mutations in the gene IKZF1 that confer a higher likelihood of developing pediatric acute lymphocytic leukemia (ALL).

6 Dec 2016

Experimental T-cell therapy shows promise in preventing AML relapse

Fred Hutchinson Cancer Research Center announced promising results from an early trial in which patients with high-risk acute myeloid leukemia received genetically engineered immune cells.

6 Dec 2016

Dual therapy safe and effective in patients with recurrent Hodgkin lymphoma

The combination of two new drugs that harness the body's immune system is safe and effective, destroying most cancer cells in 64 percent of patients with recurrent Hodgkin lymphoma, according to the results of an early-phase study.

6 Dec 2016

Simple, coordinated approach can improve chances of survival for high-risk AML patients

New research shows that quickly identifying patients with high-risk acute myeloid leukemia (AML), and speeding the process to find them a stem cell donor and performing the transplant earlier, can significantly improve their chances of surviving for at least two years after diagnosis without a relapse.

5 Dec 2016

$Combination treatment produces better outcomes in erythropoietin-refractory MDS patients, study shows$

Combination treatment produces better outcomes in erythropoietin-refractory MDS patients, study shows

Patients with myelodysplastic syndromes (MDS) suffer from a reduction in the number of different types of blood cells, including red blood cells leading to the development of anemia.

4 Dec 2016

Researchers develop portable sensor for fast, accurate assessment of blood's clotting ability

Case Western Reserve University researchers have developed a portable sensor that can assess the clotting ability of a person's blood 95 times faster than current methods—using only a single drop of blood.

4 Dec 2016

Hemophilia B patients produce near-normal levels of clotting factor IX after gene therapy, study shows

Researchers are reporting the highest and most sustained levels to date of the essential blood-clotting factor IX in patients with the inherited bleeding disorder hemophilia B.

4 Dec 2016

Clonal hematopoiesis may help predict cancer patients at risk for fatal form of leukemia

Patients successfully treated for breast, colon and other cancers can go on to develop an often-fatal form of leukemia, sometimes years after completion of treatment, due to a genetic mutation leading to secondary malignancies known as therapy-related myeloid neoplasms (t-MNs).

4 Dec 2016

MSHS introduces DigniCap scalp cooling system to reduce chemotherapy-induced hair loss

The Mount Sinai Health System announced the launch of the DigniCap scalp cooling system, which was recently cleared by the U.S. Food and Drug Administration to reduce the likelihood of chemotherapy-induced hair loss in women with breast cancer, in three of its cancer center locations.

1 Dec 2016

Penn researchers use CRISPR/Cas9 gene targeting approach to treat hemophilia B in mice

CRISPR/Cas9, a powerful genome editing tool, is showing promise for efficient correction of disease-causing mutations.

1 Dec 2016

Preventative strategy in stem cell transplant recipients may help thwart C. diff infections

It may be possible to safely prevent one of the most common - and costly to treat - infections contracted by hospitalized patients undergoing bone marrow transplantation for the treatment of blood cancers, according to a study from the Abramson Cancer Center at the University of Pennsylvania.

29 Nov 2016

Researchers reveal mechanism for side effects of drug used for treating hematological malignancies

A team of Japanese researchers revealed the mechanism for side effects such as fever and bone pain caused by G-CSF, which is widely used for peripheral blood hematopoietic stem cell harvesting (PBSCH).

25 Nov 2016

New color-coding tool sheds light on blood disorders, cancers by tracking clonal stem cells

A new color-coding tool is enabling scientists to better track live blood stem cells over time, a key part of understanding how blood disorders and cancers like leukemia arise, report researchers in Boston Children's Hospital's Stem Cell Research Program.

22 Nov 2016

Hematology News and Research

Further Reading

Leukaemia patients could safely reduce side effects of drug by cutting dose in half, study shows

Researchers unveil new role of thymic dendritic cells in controlling T lymphocyte egress into the blood

Additions to standard therapy do not improve progression-free survival in patients with multiple myeloma

Research findings point to inherited genetic basis of ALL risk in children

Experimental T-cell therapy shows promise in preventing AML relapse

Dual therapy safe and effective in patients with recurrent Hodgkin lymphoma

Simple, coordinated approach can improve chances of survival for high-risk AML patients

Combination treatment produces better outcomes in erythropoietin-refractory MDS patients, study shows

Researchers develop portable sensor for fast, accurate assessment of blood's clotting ability

Hemophilia B patients produce near-normal levels of clotting factor IX after gene therapy, study shows

Clonal hematopoiesis may help predict cancer patients at risk for fatal form of leukemia

MSHS introduces DigniCap scalp cooling system to reduce chemotherapy-induced hair loss

Penn researchers use CRISPR/Cas9 gene targeting approach to treat hemophilia B in mice

Preventative strategy in stem cell transplant recipients may help thwart C. diff infections

Researchers reveal mechanism for side effects of drug used for treating hematological malignancies

New color-coding tool sheds light on blood disorders, cancers by tracking clonal stem cells

Study offers genetic explanation why cancer occurs commonly in males than females

Scientists develop genetically engineered T cells with fusion inhibitor to disrupt HIV's harpoon

T cell channel could be potential new target for treating head and neck cancers

UT Physicians expands Sickle Cell Center to accommodate growing number of patients

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo