Hemoglobin News and Research

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ORAL Solo Phase 3 study shows tasocitinib reduces signs and symptoms of active RA

Pfizer Inc. today announced results of ORAL Solo (1045), a Phase 3 study that showed tasocitinib (CP-690,550), an investigational, novel, oral JAK inhibitor, administered as monotherapy met two primary endpoints, demonstrating a statistically significant reduction in signs and symptoms of moderately to severely active rheumatoid arthritis (RA) and improvement in physical function as measured by ACR20 response rates and mean change in HAQ-DI, respectively, versus placebo at three months.

9 Nov 2010

Combination of optical and x-ray imaging may improve diagnostic accuracy of breast screening

By combining optical and x-ray imaging, radiologists may be better able to distinguish cancer from benign lesions in the breast, according to a new study published in the online edition and January issue of Radiology.

9 Nov 2010

Skin to blood transformation in the lab

In a new study scientists have successfully transformed human skin cells into blood without first being sent through a primordial, stem-cell-like state. The findings were published online in the journal Nature. Earlier work has shown that fibroblast cells from mouse skin, treated with the right cocktail of chemicals, can be transformed into neurons and heart muscle. This is a first with human cells.

7 Nov 2010

NormOxys' OXY111A candidate selected as ‘Top 10 to Watch’ at Windhover's meeting

NormOxys Inc., a biotechnology company developing a novel class of small molecule drugs which enhance the body's ability to deliver oxygen to diseased tissues and organs, today announced that OXY111A, its clinical stage candidate for the treatment of chronic heart failure and cancer, has been selected as one of Windover's "Top 10 Cardiovascular/Metabolic Projects to Watch."

4 Nov 2010

New noninvasive technique to detect methemoglobin level

Potentially harmful levels of methemoglobin which can build up in patients receiving certain anesthetics are detectable using a new, noninvasive monitoring technique called pulse CO-oximetry, reports a study in the November issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS).

4 Nov 2010

Georgia Tech hosts symposium to discuss sickle cell disease

Georgia Tech will host the Sickle Cell Disease Symposium bringing together researchers, policy experts and community advocates to discuss the latest research and strategies for future success in combating this complex and debilitating blood disorder. The symposium begins at Georgia Tech's Institute for Bioengineering and Bioscience on November 4 and concludes the evening of November 5.

4 Nov 2010

Positive preliminary data from Protalix's taliglucerase alfa switchover trial for Gaucher disease

Protalix BioTherapeutics, Inc., announced today positive preliminary data from the first 15 patients that completed the Company's nine month, worldwide, multi-center, open-label, switchover trial of taliglucerase alfa for the treatment of Gaucher disease under a protocol cleared by the U.S. Food and Drug Administration (FDA). The data indicate that patients can safely be switched to taliglucerase alfa from imiglucerase (Cerezyme®).

2 Nov 2010

Boehringer to present data of SOUND-C1 Phase Ib study for HCV treatment at AASLD Meeting

Boehringer Ingelheim announced results from a Phase Ib study, SOUND-C1, that showed the combination of two oral hepatitis C virus (HCV) compounds, the protease inhibitor BI 201335 and the polymerase inhibitor BI 207127, with ribavirin reduced viral load to the lower limit of quantifiable levels in HCV treatment-naïve patients.

1 Nov 2010

BioMedix receives ONC-ATCB 2011/2012 certification for TRAKnet Practice Management Software

BioMedix announced today that TRAKnet Practice Management Software 2.0 is 2011/2012 compliant and was certified as a Complete EHR on October 28th, 2010 by the Certification Commission for Health Information Technology (CCHIT®), an ONC-ATCB, in accordance with the applicable Eligible Provider certification criteria adopted by the Secretary of Health and Human Services.

30 Oct 2010

Nanomedicine Center for Nucleoprotein Machines receives $16.1 million NIH award

The Georgia Tech-led Nanomedicine Center for Nucleoprotein Machines has received an award of $16.1 million for five years as part of its renewal by the National Institutes of Health (NIH). The eight-institution research team plans to pursue development of a clinically viable gene correction technology for single-gene disorders and demonstrate the technology's efficacy with sickle cell disease.

29 Oct 2010

CHORI hosts 2nd annual international Advanced Workshop on Sickle Cell Disease

Children's Hospital & Research Center Oakland is hosting the 2nd annual international Advanced Workshop on Sickle Cell Disease October 28 and 29. This impressive conference will bring together hematologists from Pakistan, Saudi Arabia, Mexico, Venezuela, Brazil, and beyond, and the premier sickle cell experts from the United States for a dialogue on research, comprehensive care, and new treatments and therapies.

27 Oct 2010

Bristol-Myers Squibb 2010 third quarter U.S. net sales increases 4% to $3.1 billion

Bristol-Myers Squibb Company today reported results for the third quarter of 2010. Highlights in the quarter included: the presentation of new data on investigational compounds in the diabetes and cardiovascular disease franchises at major medical meetings; the completion of important regulatory milestones in the oncology, diabetes and immunoscience franchises; the acquisition of ZymoGenetics; and double-digit EPS growth. The company also confirmed guidance for 2010.

26 Oct 2010

High erythropoietin levels predict higher mortality

High erythropoietin levels in people over age 85 indicate a higher risk of death, according to a study published in CMAJ.

26 Oct 2010

Rockwell Medical announces design of Phase III development program for Soluble Ferric Pyrophosphate

Rockwell Medical, a fully-integrated biopharmaceutical company offering innovative products and services targeting end-stage renal disease (ESRD), chronic kidney disease (CKD), and iron-deficiency anemia, announced today the design of its Phase III development program for Soluble Ferric Pyrophosphate (SFP) as a continuous iron replacement therapeutic.

20 Oct 2010

New brush optrode improves optical scanning of brain activity

One of the main techniques for measuring and monitoring mental activity, called functional near infrared spectroscopy (fNIRS), can often be impaired because a person's hair gets in the way. But now, thanks to a team of researchers at the University of Texas at Dallas and the University of Texas at Arlington, a novel device called a "brush optrode" is providing increased sensitivity with fiber tips designed to thread through hair to enhance scalp contact.

20 Oct 2010

Nitric oxide inhalation reduces pain in sickle cell disease patients

Inhaling nitric oxide appears to safely and effectively reduce pain crises in adults with sickle cell disease, researchers report.

20 Oct 2010

Amgen to review study results of ESA in chronic renal failure patients with FDA and CRDAC

Amgen will review the results from TREAT (the Trial to Reduce Cardiovascular Events with Aranesp® Therapy) and will discuss how these results inform the appropriate use of erythropoiesis-stimulating agents (ESAs) for chronic renal failure (CRF) patients at today's meeting of the Food and Drug Administration's (FDA) Cardiovascular and Renal Drugs Advisory Committee (CRDAC).

19 Oct 2010

Peer partner program helps diabetic patients to manage their conditions

Phone calls with a peer facing the same self-management challenges helped diabetes patients manage their conditions and improved their blood sugar levels better than those who used traditional nurse care management services alone, according to research from the University of Michigan Health System.

19 Oct 2010

OrSense's NBM 200MP non-invasive Hb measurement system more accurate than invasive POC devices

OrSense Ltd., developer of monitors for non-invasive measurements of various blood parameters, presented in an oral presentation at the American Society of Anesthesiologists (ASA) annual meeting in San Diego, results showing that hemoglobin (Hb) measurements obtained by its NBM 200MP, a non-invasive Hb measurement system, showed accurate performance during hemorrhage conditions compared with invasive point of care (POC) devices.

18 Oct 2010

NBM 200 system accurately measures hemoglobin level

OrSense Ltd., developer of monitors for non-invasive measurements of various blood parameters, presented today at the AABB Annual Meeting & CTTXPO 2010, in Baltimore, Maryland, results showing that hemoglobin (Hb) measurements obtained by its NBM 200, a non-invasive Hb measurement system for anemia screening, showed accurate performance compared with invasive point of care (POC) devices.

11 Oct 2010

Hemoglobin News and Research

ORAL Solo Phase 3 study shows tasocitinib reduces signs and symptoms of active RA

Combination of optical and x-ray imaging may improve diagnostic accuracy of breast screening

Skin to blood transformation in the lab

NormOxys' OXY111A candidate selected as ‘Top 10 to Watch’ at Windhover's meeting

New noninvasive technique to detect methemoglobin level

Georgia Tech hosts symposium to discuss sickle cell disease

Positive preliminary data from Protalix's taliglucerase alfa switchover trial for Gaucher disease

Boehringer to present data of SOUND-C1 Phase Ib study for HCV treatment at AASLD Meeting

BioMedix receives ONC-ATCB 2011/2012 certification for TRAKnet Practice Management Software

Nanomedicine Center for Nucleoprotein Machines receives $16.1 million NIH award

CHORI hosts 2nd annual international Advanced Workshop on Sickle Cell Disease

Bristol-Myers Squibb 2010 third quarter U.S. net sales increases 4% to $3.1 billion

High erythropoietin levels predict higher mortality

Rockwell Medical announces design of Phase III development program for Soluble Ferric Pyrophosphate

New brush optrode improves optical scanning of brain activity

Nitric oxide inhalation reduces pain in sickle cell disease patients

Amgen to review study results of ESA in chronic renal failure patients with FDA and CRDAC

Peer partner program helps diabetic patients to manage their conditions

OrSense's NBM 200MP non-invasive Hb measurement system more accurate than invasive POC devices

NBM 200 system accurately measures hemoglobin level

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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