Infectious Diseases News and Research

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Paxlovid treatment in 20% of COVID-19 patients could avert 850,000 hospitalizations, save up to $170 billion

A study in the Emerging Infectious Diseases journal shows treating 20% of COVID-19 patients with Paxlovid could save up to 0.85 million lives and reduce the economic burden by US $170.17 billion in the US.

14 Jan 2024

Ancient DNA traces multiple sclerosis origins to 5,000-year-old migrations

Researchers create the world's largest ancient human gene bank, linking genes to multiple sclerosis risk and tracing its origins to migrations 5,000 years ago.

13 Jan 2024

UVA researchers join international consortium to study climate-related childhood diarrhea

UVA Health researchers have joined a new international consortium that will work to understand how climate change could affect dangerous diarrheal diseases, a leading cause of death for children under 5 years old.

13 Jan 2024

New study offers hope for reducing malaria in pregnant women living with HIV

In women living with HIV, preventive treatment with DHA-PPQ is a safe and effective strategy to prevent malaria during pregnancy, according to the final results of MAMAH, a clinical trial funded by the European & Developing Countries Clinical Trials Partnership (EDCTP) and coordinated by the Barcelona Institute for Global Health (ISGlobal), an institution supported by "la Caixa" Foundation.

12 Jan 2024

Researchers uncover role of persister cells in antibiotic resistance

Antibiotic overuse can lead to antibiotic resistance, but classic antibiotic resistance might not completely explain why antibiotics sometimes fail.

12 Jan 2024

New molecule targets key protein in autoimmune diseases

Scientists from Scripps Research have developed a small molecule that blocks the activity of a protein linked to autoimmune diseases, including systemic lupus erythematosus (SLE) and Crohn's disease.

11 Jan 2024

University of Oxford launches first-in-human trial of the ChAdOx1 NipahB vaccine

The University of Oxford has launched a new clinical trial to test a vaccine to protect people against deadly Nipah virus.

11 Jan 2024

$In a fractious rerun, GOP rivals Haley and Desantis debate health care. Trump sits it out.$

In a fractious rerun, GOP rivals Haley and Desantis debate health care. Trump sits it out.

The race to win the quickly approaching Iowa caucuses was the theme running through Wednesday night's Republican presidential debate hosted by CNN at Drake University in Des Moines, Iowa. Front-runner Donald Trump was again absent and only two other candidates made the cut: Florida Gov. Ron DeSantis and former South Carolina Gov. Nikki Haley.

11 Jan 2024

A universal coronavirus vaccine could provide substantial health and economic benefits

What if scientists had developed a universal coronavirus vaccine in the years prior to 2020 so that it was available at the start of the COVID-19 pandemic?

11 Jan 2024

Hospital surfaces harbor pathogens despite cleaning, study finds

A new study published today in the American Journal of Infection Control (AJIC) reports microbial contamination - including pathogenic and potentially pathogenic bacteria - on high-touch hospital surfaces despite compliance with recommended disinfection protocols.

11 Jan 2024

Blocking sugar molecules stops flu virus spread in mice

Scientists have long known that some viruses and bacteria begin infections by latching first onto sugar molecules on the surfaces of cells lining the sinuses and throat of mammals, including humans.

11 Jan 2024

Phylogenomic analysis to generate early warning signs for COVID-19 waves

The Transmission Fitness Polymorphism (TFP) scanner analysis pipeline to detect severe acute respiratory syndrome coronavirus 2.

11 Jan 2024

New intranasal vaccine candidate triggers powerful mucosal defense against SARS-CoV-2

A team of scientists, led by Duke-NUS Medical School, has discovered a potential intranasal vaccine candidate that provides improved, longer-lasting immunity against SARS-CoV-2 viruses compared to when given as an injection.

10 Jan 2024

Study: Respiratory syncytial virus directly infects nerve cells and causes inflammation

Respiratory syncytial virus (RSV), a common infection in children and senior adults, can also infect nerve cells and trigger inflammation leading to nerve damage, according to a new Tulane University study.

10 Jan 2024

Combined vaccination and behavior change efforts averted 64% of US mpox cases, study reveals

The effectiveness of the combination of current preventive responses against monkeypox (Mpox).

10 Jan 2024

Nasal drops with IgA antibodies may protect against COVID-19 and future variants

Researchers at Karolinska Institutet in Sweden have shown that nasal drops with IgA antibodies can protect mice from SARS-CoV-2 infection.

10 Jan 2024

BCG vaccine's impact on innate immunity explained at cellular level

Bacillus Calmette-Guérin (BCG) is one of the world’s oldest and most widely used vaccines. It was developed in the early 20th century to provide protection from tuberculosis.

9 Jan 2024

Zika virus effective in eliminating neuroblastoma tumors in mice, study finds

Injecting neuroblastoma tumors with Zika virus shrank or eliminated those tumors in studies with mice, suggesting that the virus could someday serve as an effective cancer therapy, according to a study led by Nemours Children's Health researchers and published today in Cancer Research Communications, a journal of the American Association for Cancer Research.

9 Jan 2024

SARS-CoV-2 BA.2.86 shows increased lung targeting despite vaccine effectiveness

New research shows that the recently emerged BA.2.86 omicron subvariant of the virus that causes COVID-19 can be neutralized by bivalent mRNA vaccine-induced antibodies in the blood, which explains why this variant did not cause a widespread surge as previously feared.

8 Jan 2024

Disease-causing bacteria use molecular "barcode" to distinguish between beneficial and toxic molecules

Researchers at McMaster University have discovered a molecular "barcode" system used by disease-causing bacteria to distinguish between beneficial and toxic molecules.

8 Jan 2024

Infectious Diseases News and Research

Paxlovid treatment in 20% of COVID-19 patients could avert 850,000 hospitalizations, save up to $170 billion

Ancient DNA traces multiple sclerosis origins to 5,000-year-old migrations

UVA researchers join international consortium to study climate-related childhood diarrhea

New study offers hope for reducing malaria in pregnant women living with HIV

Researchers uncover role of persister cells in antibiotic resistance

New molecule targets key protein in autoimmune diseases

University of Oxford launches first-in-human trial of the ChAdOx1 NipahB vaccine

In a fractious rerun, GOP rivals Haley and Desantis debate health care. Trump sits it out.

A universal coronavirus vaccine could provide substantial health and economic benefits

Hospital surfaces harbor pathogens despite cleaning, study finds

Blocking sugar molecules stops flu virus spread in mice

Phylogenomic analysis to generate early warning signs for COVID-19 waves

New intranasal vaccine candidate triggers powerful mucosal defense against SARS-CoV-2

Study: Respiratory syncytial virus directly infects nerve cells and causes inflammation

Combined vaccination and behavior change efforts averted 64% of US mpox cases, study reveals

Nasal drops with IgA antibodies may protect against COVID-19 and future variants

BCG vaccine's impact on innate immunity explained at cellular level

Zika virus effective in eliminating neuroblastoma tumors in mice, study finds

SARS-CoV-2 BA.2.86 shows increased lung targeting despite vaccine effectiveness

Disease-causing bacteria use molecular "barcode" to distinguish between beneficial and toxic molecules

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