Omicron News and Research

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Decoy ACE2 nanoparticles block the entry of SARS-CoV-2 into cells

In a recent study posted to the bioRxiv* preprint server, researchers reported that nanoparticles could prevent severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) cell entry.

10 May 2022

Evasion of COVID-19 vaccine-medicated mucosal immunity by SARS-CoV-2 Omicron

Researchers depicted the evasion of the SARS-CoV-2 Omicron variant to mucosal immunity in SARS-CoV-2 vaccine recipients.

10 May 2022

Simulating molecular dynamics of SARS-CoV-2 spike variants in the locked conformation

Researchers retrieved the first-ever sequenced spike (S) protein structures of the original Wuhan-Hu 1 SARS-CoV-2 strain, the Alpha, Delta, Delta-plus variants, and Omicron sub-variants BA.1 and BA.2 and compared their structural and molecular level variations.

10 May 2022

Heightened antibody responses in COVID-19 booster vaccinated individuals following SARS-CoV-2 Omicron

Investigators illustrated that a SARS-CoV-2 Omicron infection post-booster vaccination imparts robust, long-lasting immunity against future re-infections.

10 May 2022

Research highlight reports on the observed differences in transmissibility and pathogenicity of Omicron vs. earlier variants of SARS-CoV-2

A new paper published in Signal Transduction and Targeted Therapy reports the observed differences in transmissibility and pathogenicity of Omicron vs. earlier variants of SARS-CoV-2.

10 May 2022

SARS-CoV-2 Omicron infection boosts Delta immunity in those who have been vaccinated

A new study published in the journal Nature aimed to determine the extent to which Omicron infection elicits protection against other SARS-CoV-2 variants in both vaccinated and unvaccinated individuals.

10 May 2022

mRNA boosters enhance neutralization of SARS-CoV-2 BA.1, BA.2 and BA.3

A study recently published in the journal Cell Host & Microbe has described that all three sublineages of the omicron variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exhibit similar host cell entry efficiency and are neutralized equally by antibodies generated in response to coronavirus disease 2019 (COVID-19) booster vaccination

10 May 2022

More evidence that pediatric COVID vaccination prevents MIS-C

Researchers designed a nationwide pediatric COVID-19 research project based on real-time data since the early phase of the pandemic.

9 May 2022

Third BNT162b2 dose elicits more durable immune response than second dose

Researchers evaluated the durability of immune responses post-third dose of the BNT162b2 vaccine against SARS-CoV-2.

9 May 2022

Age-specific variation of asymptomatic COVID-19 infections

Researchers assessed asymptomatic SARS-CoV-2 infection according to age.

9 May 2022

Study investigates the cause of lymphopenia as seen in COVID-19 patients

Researchers explored the underlying mechanism resulting in thymic atrophy and subsequent lymphopenia in COVID-19 patients.

9 May 2022

COVID-19 booster or additional primary vaccination dose against SARS-CoV-2 Omicron in nursing home occupants

A recent study assessed the efficacy of SARS-CoV-2 primary series vaccination, additional initial dose, or booster shot against the SARS-CoV-2 Omicron infection in the nursing home.

9 May 2022

The potential impact of oral vaccination against COVID-19 on transmission to naïve individuals studied in a hamster infection model

A recent article published in Science Translational Medicine demonstrated that mucosally delivered adenovirus type 5 (Ad5)-based COVID-19 vaccination minimized COVID-19 transmission and severity.

9 May 2022

Effectiveness of BNT162b2 third dose against Omicron-associated severe disease

Researchers analyzed the effectiveness of the SARS-CoV-2 BNT162b2 third vaccine dose against SARS-CoV-2 Omicron-induced severe infection nearly seven months post-vaccination.

9 May 2022

Evidence of croup associated with SARS-CoV-2

A new study published in the Journal of Pediatric Infectious Diseases Society aimed to characterize the clinical features of SARS-CoV-2-associated croup among children presenting to the ED during the phase when Omicron variant transmission was high.

9 May 2022

Using PCR-based genotyping to detect SARS-CoV-2 delta-omicron coinfection

In a recently published ‘Letter to the Editor’ in the journal Microbiology Spectrum, scientists have described the procedure of polymerase chain reaction (PCR)-based genotyping in identifying delta-omicron coinfection in clinical samples.

9 May 2022

ZF2001 vaccine safe and effective against symptomatic and severe-to-critical COVID

A new study published in the New England Journal of Medicine has discussed the efficacy and safety profile of the ZF2001 vaccine in adults, based on a randomized, placebo-controlled, multinational, double-blind phase 3 trial.

9 May 2022

A guide to help you keep up with the omicron subvariants

Two years into the coronavirus pandemic, Americans can be forgiven if they've lost track of the latest variants circulating nationally and around the world. We've heard of the alpha, beta, gamma, delta, and omicron variants, but a new Greek-letter variant hasn't come onto the scene in almost half a year.

6 May 2022

SARS-CoV-2 variants are not evolving to escape from T cell-mediated immunity

In a recent study posted to the bioRxiv* pre-print server, researchers demonstrated that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants did not evolve further to escape from T cell-mediated immunity.

6 May 2022

Variolation - Face masks might reduce COVID-19 severity

In a recent study published in the Journal of the Royal Society Interface, researchers developed an epidemiological model to demonstrate that mask-induced variolation causes milder severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

5 May 2022

Omicron News and Research

Decoy ACE2 nanoparticles block the entry of SARS-CoV-2 into cells

Evasion of COVID-19 vaccine-medicated mucosal immunity by SARS-CoV-2 Omicron

Simulating molecular dynamics of SARS-CoV-2 spike variants in the locked conformation

Heightened antibody responses in COVID-19 booster vaccinated individuals following SARS-CoV-2 Omicron

Research highlight reports on the observed differences in transmissibility and pathogenicity of Omicron vs. earlier variants of SARS-CoV-2

SARS-CoV-2 Omicron infection boosts Delta immunity in those who have been vaccinated

mRNA boosters enhance neutralization of SARS-CoV-2 BA.1, BA.2 and BA.3

More evidence that pediatric COVID vaccination prevents MIS-C

Third BNT162b2 dose elicits more durable immune response than second dose

Age-specific variation of asymptomatic COVID-19 infections

Study investigates the cause of lymphopenia as seen in COVID-19 patients

COVID-19 booster or additional primary vaccination dose against SARS-CoV-2 Omicron in nursing home occupants

The potential impact of oral vaccination against COVID-19 on transmission to naïve individuals studied in a hamster infection model

Effectiveness of BNT162b2 third dose against Omicron-associated severe disease

Evidence of croup associated with SARS-CoV-2

Using PCR-based genotyping to detect SARS-CoV-2 delta-omicron coinfection

ZF2001 vaccine safe and effective against symptomatic and severe-to-critical COVID

A guide to help you keep up with the omicron subvariants

SARS-CoV-2 variants are not evolving to escape from T cell-mediated immunity

Variolation - Face masks might reduce COVID-19 severity

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