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Study reveals genes that cause loss of lung function in active smokers

Chronic Obstructive Pulmonary Disease (COPD) is a disease caused by cigarette smoking that reduces lung function and causes difficulty breathing. It is the third leading cause of death worldwide. Current treatments for COPD only affect symptoms, not progression. Identifying who is going to get COPD before they get it is key to figuring out how to intercept the disease at an early stage.

12 May 2021

HIV patients are more likely to die from COVID-19 infection

Over the past year, studies have revealed that certain pre-existing conditions, such as cancer, diabetes and high blood pressure, can increase a person's risk of dying from COVID-19.

12 May 2021

Normalizing cholesterol metabolism in microglia alleviates chronic neuropathic pain

Chemotherapy can induce a painful peripheral neuropathy (CIPN), a chronic condition and common adverse effect for cancer patients undergoing treatment.

10 May 2021

Israeli study shows real-world efficacy of Pfizer-BioNTech’s COVID-19 vaccine

Researchers have conducted an analysis of nationwide surveillance data from Israel demonstrating the real-world effectiveness of Pfizer-BioNTech’s BNT162b2 vaccine at protecting against infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

6 May 2021

This small Canadian drugmaker wants to make J&J vaccines for poor nations. It needs more than a patent waiver.

Biolyse Pharma Corp., which makes a cancer medication, was gearing up to start making generic biologic drugs, made from living organisms. Then the pandemic hit.

6 May 2021

KHN’s ‘What the Health?’: Sharing vaccines with the world

The Biden administration — keeping a campaign promise — announced it would back a temporary waiver of patent protections for the covid-19 vaccines, arousing the ire of the drug industry.

6 May 2021

Covid shot in the arm not enough to keep pharmacies in business

Tobin's pharmacy and department store had already stocked its shelves with Easter and Mother's Day items last spring, and the staff had just placed the Christmas orders.

5 May 2021

Study shows potential of human mesenchymal stem cells to treat chronic lung infections

A study released today in STEM CELLS Translational Medicine offers hope for those suffering from a chronic, difficult to treat condition called non-tuberculous mycobacteria (NTM) lung infection.

4 May 2021

Democrats disagree about how to spend potential prescription drug windfall

One of the few surprises in President Joe Biden's social safety-net proposal, the American Families Plan, was something that didn't make it into the final version: any mention of reining in the price of prescription drugs.

4 May 2021

Detecting rare blood clots was a win, but US vaccine safety system still has gaps

The quick detection of an ultra-rare blood clotting reaction in some Covid-19 vaccine recipients showed the power of a federal warning system for vaccine safety issues, but experts worry that blind spots in the program could hamper detection of other unexpected side effects.

3 May 2021

CVS and Walgreens have wasted more vaccine doses than most states combined

Two national pharmacy chains that the federal government entrusted to inoculate people against Covid-19 account for the lion's share of wasted vaccine doses, according to government data obtained by KHN.

3 May 2021

FDA approves higher dose naloxone hydrochloride nasal spray product to combat opioid overdose

The U.S. Food and Drug Administration announced today the approval of a higher dose naloxone hydrochloride nasal spray product to treat opioid overdose. The newly approved product delivers 8 milligrams (mg) of naloxone into the nasal cavity. The FDA had previously approved 2 mg and 4 mg naloxone nasal spray products.

30 Apr 2021

Researchers discover how SARS-CoV-2 hijacks human cell machinery to blunt immune response

Researchers at University of California San Diego School of Medicine have discovered one way in which SARS-CoV-2, the coronavirus that causes COVID-19, hijacks human cell machinery to blunt the immune response, allowing it to establish infection, replicate and cause disease.

29 Apr 2021

New method could be used to develop more effective treatments for cancer, metabolic disorders

Researchers from the University of Copenhagen have developed a new method that makes it possible to control human hormones and metabolism.

28 Apr 2021

New AI-driven diagnostics technique could transform treatment for bowel cancer

A test which uses artificial intelligence to measure proteins present in some patients with advanced bowel cancer could hold the key to more targeted treatment, according to research published today.

27 Apr 2021

Study offers insight into how damage to airways of the lung develops into pre-cancer lesions

Lung carcinomas are the leading cause of cancer-related deaths in the United States and worldwide. Lung squamous cell carcinomas (non-small cell lung cancers that arise in the bronchi of the lungs and make up approximately 30 percent of all lung cancers) are poorly understood, particularly with respect to the cell type and signals that contribute to disease onset.

26 Apr 2021

NIH to conduct large trial for COVID-19 polyclonal antibody therapies

The National Institutes of Health (NIH) in the USA are to conduct a large-scale clinical trial to evaluate a new fully-human polyclonal antibody therapy targeted at severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative pathogen of coronavirus disease 2019 (COVID-19).

23 Apr 2021

DNA vaccine candidate induces potent immunity, offers protective efficacy in non-human primate models

A synthetic DNA vaccine candidate for Middle East respiratory syndrome coronavirus (MERS-CoV) developed at The Wistar Institute induced potent immune responses and afforded protective efficacy in non-human primate (NHP) models when given intradermally in abbreviated, low-dose immunization regimen.

23 Apr 2021

Clinical trial examines metabolic effects of natural compound NMN in people

A natural compound previously demonstrated to counteract aspects of aging and improve metabolic health in mice has clinically relevant effects in people, according to new research at Washington University School of Medicine in St. Louis.

22 Apr 2021

KHN’s ‘What the Health?’: Picking up the pace of undoing Trump policies

The Biden administration is speeding up the pace of efforts to undo Trump administration health policies.

22 Apr 2021

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Pharmaceuticals News and Research

Study reveals genes that cause loss of lung function in active smokers

HIV patients are more likely to die from COVID-19 infection

Normalizing cholesterol metabolism in microglia alleviates chronic neuropathic pain

Israeli study shows real-world efficacy of Pfizer-BioNTech’s COVID-19 vaccine

This small Canadian drugmaker wants to make J&J vaccines for poor nations. It needs more than a patent waiver.

KHN’s ‘What the Health?’: Sharing vaccines with the world

Covid shot in the arm not enough to keep pharmacies in business

Study shows potential of human mesenchymal stem cells to treat chronic lung infections

Democrats disagree about how to spend potential prescription drug windfall

Detecting rare blood clots was a win, but US vaccine safety system still has gaps

CVS and Walgreens have wasted more vaccine doses than most states combined

FDA approves higher dose naloxone hydrochloride nasal spray product to combat opioid overdose

Researchers discover how SARS-CoV-2 hijacks human cell machinery to blunt immune response

New method could be used to develop more effective treatments for cancer, metabolic disorders

New AI-driven diagnostics technique could transform treatment for bowel cancer

Study offers insight into how damage to airways of the lung develops into pre-cancer lesions

NIH to conduct large trial for COVID-19 polyclonal antibody therapies

DNA vaccine candidate induces potent immunity, offers protective efficacy in non-human primate models

Clinical trial examines metabolic effects of natural compound NMN in people

KHN’s ‘What the Health?’: Picking up the pace of undoing Trump policies

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