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Discovery of gene that increases susceptibility to Crohn's disease

Researchers at McGill University, the Research Institute of the McGill University Health Centre (RI MUHC) and the McGill University and Génome Québec Innovation Centre, along with colleagues at other Canadian and Belgian institutions, have discovered DNA variations in a gene that increases susceptibility to developing Crohn's disease.

8 Jan 2009

New genetic markers for ulcerative colitis could lead to treatment

An international consortium of researchers, including major contribution from a team led by Dr. John D. Rioux, a professor of medicine at the Université de Montréal and the Montreal Heart Institute, has identified genetic markers associated with risk for ulcerative colitis.

8 Jan 2009

Gene abnormality found to predict childhood leukemia relapse

Scientists have identified mutations in a gene that predict a high likelihood of relapse in children with acute lymphoblastic leukemia (ALL).

8 Jan 2009

Latest genetic research on ADHD

A special issue of American Journal of Medical Genetics (AJMG): Part B: Neuropsychiatric Genetics presents a comprehensive overview of the latest progress in genetic research of Attention Deficit/Hyperactivity Disorder (ADHD).

7 Jan 2009

Genomics in China

Ten years ago, the Chinese National Human Genome Center at Shanghai (South Center, hereafter) was established in the Zhangjiang HiTech Park of Pudong District in Shanghai.

7 Jan 2009

Gene mutations found to predict acute lymphoblastic leukemia relapse

Scientists have identified mutations in a gene that predict a high likelihood of relapse in children with acute lymphoblastic leukemia (ALL).

7 Jan 2009

Widespread antiviral drug use can accelerate the evolution of drug resistance in viruses

Influenza's ability to resist the effects of cheap and popular antiviral agents in Asia and Russia should serve as a cautionary tale about U.S. plans to use the antiviral Tamiflu in the event of widespread avian flu infection in humans, scientists say.

7 Jan 2009

Studies offer guide as protein interaction mapping comes of age

During the past 20 years, researchers have identified thousands of cell protein interactions, with the ultimate goal of inventorying all that occur within cells of various organisms - a comprehensive catalogue known as the interactome.

6 Jan 2009

Discovery of new way for bacteria to transfer toxic genes to unrelated bacterial species

In a laboratory experiment, the scientists from NYU School of Medicine discovered that Staphylococcus aureus, a notorious bacterium that causes toxic shock syndrome and many other types of infections and is the scourge of hospitals nationwide due to its growing antibiotic resistance, could co-opt viral parasites as secret pipelines for transferring toxin genes to vastly different bacterial species.

6 Jan 2009

Research initiative looks at helpful bacteria found on the skin

The study of ancient microbes may not seem consequential, but such pioneering research at the University of Oklahoma has implications for the state of modern human health.

5 Jan 2009

Metadherin gene linked to metastasis of breast cancer

A team of researchers at Princeton University and The Cancer Institute of New Jersey has identified a long-sought gene that is fatefully switched on in 30 to 40 percent of all breast cancer patients, spreading the disease, resisting traditional chemotherapies and eventually leading to death.

5 Jan 2009

Researchers show mechanisms that regulate DNA damage control and replication

Scientists at Burnham Institute for Medical Research (Burnham) have demonstrated important new roles for the protein kinase complex Cdc7/Dbf4 or Cdc7/Drf1 (Ddk) in monitoring damage control during DNA replication and reinitiating replication following DNA repair.

5 Jan 2009

Discovery of new genetic markers for ulcerative colitis

An international team led by University of Pittsburgh School of Medicine researchers has identified genetic markers associated with risk for ulcerative colitis.

5 Jan 2009

Culprit found in rare type of baldness

Scientists in Beijing say they have discovered a genetic cause for a certain type of premature baldness and they suggest their discovery offers hope in future that those who inherit this rare type of baldness will eventually be able to keep their hair.

5 Jan 2009

New understanding of genetic signature associated with Alzheimer's disease

Scientists have new information about the complex genetic signature associated with Alzheimer's disease, the leading cause of cognitive decline and dementia in the elderly.

1 Jan 2009

In lung cancer, silencing one crucial gene disrupts normal functioning of genome

While examining patterns of DNA modification in lung cancer, a team of international researchers has discovered what they say is a surprising new mechanism.

1 Jan 2009

Few DNA repair gene variants associated with increased cancer risk

Variants of numerous DNA repair genes initially appeared to be statistically significantly associated with cancer risk in epidemiological studies.

1 Jan 2009

Researchers identify clockwork that drives a powerful virus nanomotor

Peering at structures only atoms across, researchers have identified the clockwork that drives a powerful virus nanomotor.

30 Dec 2008

Researchers identify common gene variant linked to high blood pressure

Researchers at the University of Maryland School of Medicine have identified a common gene variant that appears to influence people's risk of developing high blood pressure, according to the results of a study being published online Dec. 29, 2008 in the Proceedings of the National Academy of Sciences (PNAS).

30 Dec 2008

Hexokinase-1 gene variation associated with widely used marker of blood glucose concentration

Scientists have found that genetic variation at the hexokinase-1 gene is linked to variation in the blood concentration of glycated hemoglobin, an index of long-term blood glucose concentration widely used in the follow-up of diabetes patients.

22 Dec 2008