Liver News and Research

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Gene B-myb essential in preventing tumors

A new study has confirmed that research done with zebrafish may be able to play a critical role in learning about the genetic basis of cancer and the mutations that can lead to it - and identified one gene in particular, B-myb, whose function is essential to preventing tumors.

5 Sep 2005

Low doses of the active form of vitamin D and non-steroidal anti-inflammatory drugs form one-two punch against prostate cancer cells

Low doses of the active form of vitamin D and non-steroidal anti-inflammatory drugs, taken in combination, have been shown to act as a powerful one-two punch that knocks down the growth of prostate cancer cells.

1 Sep 2005

Study suggests cirrhosis and liver disease nearly inevitable for people with hep C

Nearly 80 percent of chronic hepatitis C sufferers who have the disease for several decades will develop cirrhosis or end-stage liver disease later in life, according to a study published today in the American Gastroenterological Association (AGA) journal Clinical Gastroenterology and Hepatology.

1 Sep 2005

Mushrooms are a great source of antioxidants

Using a new, more sensitive-testing approach they developed for fungi, Penn State food scientists have found that mushrooms are a better natural source of the antioxidant ergothioneine than either of the two dietary sources previously believed to be best

31 Aug 2005

Data show that HIV-infected older people not taking HAART have double the risk of death

HIV is often regarded as a disease of young people, due to its status as a drug-related or sexually transmitted disease. However, the number of people over age 50 who are infected with HIV is significant--and growing--according to an article in the Sept. 15 issue of Clinical Infectious Diseases, now available online.

30 Aug 2005

Top doctors in UK fear for teens with change in alcohol laws

Doctors in the UK are concerned that any relaxation in the alcohol laws will only serve to cause a rise in cirrhosis among young people.

30 Aug 2005

Molecular missing link between fasting and acute attacks of porphyria

A team of researchers has discovered a molecular missing link that helps explain why fasting brings on acute attacks of the genetic disease hepatic porphyria, according to a new report in the 26 August issue of the journal Cell.

29 Aug 2005

Coffee is the number one source of antioxidants in the U.S. diet

Coffee provides more than just a morning jolt; that steaming cup of java is also the number one source of antioxidants in the U.S. diet, according to a new study by researchers at the University of Scranton (Pa.).

29 Aug 2005

Elevated blood lactate levels may indicate poor prognosis in liver failure

A new study on fulminant hepatic failure (FHF), a sudden and severe shutdown of the liver, examined ways of determining early on whether patients would benefit from a transplant as opposed to responding to other medical treatment. The results showed that elevated blood lactate levels indicate a poor prognosis and thus the need for a transplant.

28 Aug 2005

First clinical trial of a biologic nanoparticle designed to give back to cancer patients the tumor-busting gene they have lost

The phase I clinical study will enroll 20 patients with advanced solid cancers (including most common tumor types), and is the culmination of more than a decade of work by a team of researchers led by Professor Esther H. Chang, Ph.D. at the Lombardi Comprehensive Cancer Center.

25 Aug 2005

Susceptibility to Hepatitis A in patients with chronic liver disease due to Hepatitis C virus infection: missed opportunities for vaccination

A new study examining whether patients with chronic Hepatitis C virus (HCV) were routinely vaccinated against Hepatitis A virus (HAV) found that vaccination rates were low, even though HAV vaccination is recommended for patients with chronic liver disease.

23 Aug 2005

Study examines the incidence and risk factors associated with Hepatitis C infection in rural Egypt

The prevalence of antibodies to Hepatitis C Virus (HCV) in Egypt is among the highest in the world. From the 1950s until 1982 hundreds of thousands were infected during mass campaigns to control schistosomiasis (a parasitic disease) using mass therapy with intravenous antimony compounds, but little is known about current risk factors and rates of transmission.

23 Aug 2005

Patients with primary biliary cirrhosis who are treated with methotrexate have an increased risk of death

In five randomized controlled trials involving 457 people, the authors report that for patients treated with methotrexate, as a single therapy or in combination with other drug treatment, pooled data showed a tendency toward an increased risk of death or liver transplantation. The brand names for methotrexate are Rheumatrex and Trexall.

23 Aug 2005

Gene therapy advance shows potential for developing improved treatment for hemophilia

A virus that typically infects insects could help with the development of gene therapy treatment for Hemophilia A, a condition in which even a bump on the knee can cause serious internal bleeding in people.

22 Aug 2005

Increasing sugar processing in the liver may lead to future treatments for diabetes, obesity

Researchers at the University of Minnesota have shown that increasing the concentration of a key regulator involved in glucose metabolism can improve the way the liver produces and disposes of the sugar glucose, the primary fuel of the body. Finding ways to increase that concentration could provide a treatment for diabetes and obesity.

22 Aug 2005

Protein Sirt1 points to new therapies for type 2 diabetes

Opening the possibility of new therapies for type 2 diabetes, researchers at Washington University School of Medicine in St. Louis have found that a protein called Sirt1 enhances the secretion of insulin in mice and allows them to better control blood glucose levels. Their study appears in the August 17 issue of Cell Metabolism.

18 Aug 2005

Global prevalence of kidney failure among critically ill patients

A multinational study has found that 5 to 6 percent of patients in intensive care units experience acute kidney failure, and about 60 percent of these patients die in the hospital, according to an article in the August 17 issue of JAMA: The Journal of the American Medical Association.

18 Aug 2005

Breakthrough in human stem cell research

A breakthrough in human stem cell research, producing embryonic-like cells from umbilical cord blood may substantially speed up the development of treatments for life-threatening illnesses, injuries and disabilities.

16 Aug 2005

Folates best at preventing Alzheimer's disease

According to results from a long-term study on aging, adults who eat the daily recommended allowance of folates significantly reduce their risk of developing Alzheimer's disease.

15 Aug 2005

Vitamin B reduces risk of developing Alzheimer's disease

Adults who eat the daily recommended allowance of folates - B-vitamin nutrients found in oranges, legumes, leafy green vegetables and folic acid supplements - significantly reduce their risk of developing Alzheimer's disease, according to results from a long-term National Institute on Aging study of diet and brain aging.

13 Aug 2005

Liver News and Research

Gene B-myb essential in preventing tumors

Low doses of the active form of vitamin D and non-steroidal anti-inflammatory drugs form one-two punch against prostate cancer cells

Study suggests cirrhosis and liver disease nearly inevitable for people with hep C

Mushrooms are a great source of antioxidants

Data show that HIV-infected older people not taking HAART have double the risk of death

Top doctors in UK fear for teens with change in alcohol laws

Molecular missing link between fasting and acute attacks of porphyria

Coffee is the number one source of antioxidants in the U.S. diet

Elevated blood lactate levels may indicate poor prognosis in liver failure

First clinical trial of a biologic nanoparticle designed to give back to cancer patients the tumor-busting gene they have lost

Susceptibility to Hepatitis A in patients with chronic liver disease due to Hepatitis C virus infection: missed opportunities for vaccination

Study examines the incidence and risk factors associated with Hepatitis C infection in rural Egypt

Patients with primary biliary cirrhosis who are treated with methotrexate have an increased risk of death

Gene therapy advance shows potential for developing improved treatment for hemophilia

Increasing sugar processing in the liver may lead to future treatments for diabetes, obesity

Protein Sirt1 points to new therapies for type 2 diabetes

Global prevalence of kidney failure among critically ill patients

Breakthrough in human stem cell research

Folates best at preventing Alzheimer's disease

Vitamin B reduces risk of developing Alzheimer's disease

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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