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New understanding on how cancer cells communicate

Researchers from University College London have devised a new way by which they could decipher the language cancer cells use to communicate among themselves. They found this unique method of communication between the cancer cells in organoids or collections of cells mimicking a mini organism in the lab.

17 Feb 2020

New technique helps decipher how individual cancer cells communicate with each other

Scientists have a developed a new technique to decipher how millions of individual cells are communicating with each other in miniature tumors grown in the lab, known as organoids, according to new research published in Nature Methods today (Monday).

17 Feb 2020

Intratumoral heterogeneity linked to chemotherapy resistance in small-cell lung cancer

Small cell lung cancer accounts for 14% of all lung cancers and is often rapidly resistant to chemotherapy, resulting in poor clinical outcomes.

17 Feb 2020

Coping with adult nightmares

Bad dreams or nightmares affect not only children but adults, too. Haunting nightmares can affect a person’s sleep quality and duration, but is it possible to turn off a nightmare while it is happening?

17 Feb 2020

Detailed maps of breast cancer reveal how genetic changes shape the tumor landscape

Scientists have created one of the most detailed maps of breast cancer ever achieved, revealing how genetic changes shape the physical tumor landscape, according to research funded by Cancer Research UK and published in Nature Cancer today (Monday).

17 Feb 2020

New technology enables scientists to analyze behavior of cancer cells in lab-grown tumors

New technology developed at UCL is, for the first time, enabling cancer scientists to analyze the individual behavior of millions of different cells living inside lab-grown tumors - a breakthrough which could lead to new personalised cancer treatments.

17 Feb 2020

Guideline-recommended diuretic linked to more side effects than similar antihypertensive drug

Chlorthalidone, the guideline-recommended diuretic for lowering blood pressure, causes more serious side effects than hydrochlorothiazide, a similarly effective diuretic, according to a new study led by researchers at Columbia University Irving Medical Center.

17 Feb 2020

Individual clinical judgments needed for prescribing aspirin in primary prevention

The most recent guidelines for primary prevention recommend aspirin use for individuals ages 40 to 70 years who are at higher risk of a first cardiovascular event, but not for those over 70. Yet, people over 70 are at increasingly higher risks of cardiovascular events than those under 70.

17 Feb 2020

Combination therapy for pediatric low-grade gliomas shows promise in mice

In experiments with human cells and mice, researchers at the Johns Hopkins Kimmel Cancer Center report evidence that combining the experimental cancer medication TAK228 (also called sapanisertib) with an existing anti-cancer drug called trametinib may be more effective than either drug alone in decreasing the growth of pediatric low-grade gliomas.

17 Feb 2020

Scientists find a way to block the growth of kidney cancer

Scientists at the MDC have discovered stem cells responsible for the most common form of kidney cancer. The team of Walter Birchmeier has found a way to block the growth of these tumors in three models of the disease.

17 Feb 2020

Research shows how Ebola virus interacts with human lipids

Robert Stahelin studies some of the world's deadliest viruses. Filoviruses, including Ebola virus and Marburg virus, cause viral hemorrhagic fever with high fatality rates.

16 Feb 2020

New molecular 'fishing' technology can find individual molecules in blood

Like finding a needle in a haystack, Liviu Movileanu can find a single molecule in blood. Movileanu, professor at Syracuse University, and recently graduated Ph.D. student Avinash Thakur will present their research on Monday, February 17 at the 64th Annual Meeting of the Biophysical Society in San Diego, California.

16 Feb 2020

Pioneering technique reveals structure of Parkinson's disease protein in action

The top contributor to familial Parkinson's disease is mutations in leucine-rich repeat kinase 2 (LRRK2), whose large and difficult structure has finally been solved, paving the way for targeted therapies.

16 Feb 2020

Scientists map molecular steps in the development of endometrial cancer

A new study reveals the molecular steps that bring about endometrial cancer, commonly known as uterine cancer, which is the sixth most common cancer in women across the globe.

16 Feb 2020

Scientists develop "smart" remote-control bandage for chronic wounds

People with diabetes suffer from chronic and non-healing wounds, often leading to severe infection and, eventually, amputation of the limb. The essential treatment for these wounds is the continuous application of medicines and the regular changing of bandages to prevent infection.

16 Feb 2020

New ligament repair procedure shows promise to relieve wrist pain, restore function

Over the past three decades, hand surgeon Scott Wolfe has been conducting research to find a better way to repair a common wrist injury that results in pain, disability and progressive arthritis.

16 Feb 2020

Bile duct cancer treatment could be improved by tailored medication

Treatment of patients suffering from bile duct cancer could be improved by tailoring medication to the levels of a key protein in people with the disease, according to new research.

16 Feb 2020

Study suggests potential treatment to alleviate disorders of consciousness

A small amount of electricity delivered at a specific frequency to a particular point in the brain will snap a monkey out of even deep anesthesia, pointing to a circuit of brain activity key to consciousness and suggesting potential treatments for debilitating brain disorders.

16 Feb 2020

Novel formulation allows use of toxin from rattlesnake venom to control neuropathic pain

Crotoxin, extracted from the venom of the South American rattlesnake Crotalus durissus terrificus, has been studied for almost a century for its analgesic, anti-inflammatory and antitumor activities and as an even more powerful muscle paralyzer than botulinum toxin.

16 Feb 2020

Vitamin E can safely treat fatty liver disease in patients with HIV

A type of fatty liver disease that commonly affects patients with HIV can be safely treated with vitamin E, a McGill-led study has found.

16 Feb 2020

Drugs News and Research

New understanding on how cancer cells communicate

New technique helps decipher how individual cancer cells communicate with each other

Intratumoral heterogeneity linked to chemotherapy resistance in small-cell lung cancer

Coping with adult nightmares

Detailed maps of breast cancer reveal how genetic changes shape the tumor landscape

New technology enables scientists to analyze behavior of cancer cells in lab-grown tumors

Guideline-recommended diuretic linked to more side effects than similar antihypertensive drug

Individual clinical judgments needed for prescribing aspirin in primary prevention

Combination therapy for pediatric low-grade gliomas shows promise in mice

Scientists find a way to block the growth of kidney cancer

Research shows how Ebola virus interacts with human lipids

New molecular 'fishing' technology can find individual molecules in blood

Pioneering technique reveals structure of Parkinson's disease protein in action

Scientists map molecular steps in the development of endometrial cancer

Scientists develop "smart" remote-control bandage for chronic wounds

New ligament repair procedure shows promise to relieve wrist pain, restore function

Bile duct cancer treatment could be improved by tailored medication

Study suggests potential treatment to alleviate disorders of consciousness

Novel formulation allows use of toxin from rattlesnake venom to control neuropathic pain

Vitamin E can safely treat fatty liver disease in patients with HIV

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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