Infectious Diseases News and Research

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Genetic mutation that protects against HIV increases the risk of West Nile Virus infection

A genetic mutation that protects against HIV increases the risk of developing clinical West Nile Virus infection, according to a new study appearing online on January 9th in The Journal of Experimental Medicine.

9 Jan 2006

Data establishes safety profile of new GlaxoSmithKline rotavirus vaccine candidate

Data from one of the largest infant vaccine trials ever conducted, published in the New England Journal of Medicine (NEJM), showed GlaxoSmithKline's (GSK) rotavirus vaccine candidate as effective against rotavirus disease (rotavirus gastroenteritis) in the first year of life. Rotavirus is the leading recognized cause of diarrhea-related illness and death among infants and young children.

6 Jan 2006

Risk factors for nongonococcal urethritis

The study, by Australian researchers Catriona Bradshaw, MD, and colleagues at the Melbourne Sexual Health Centre, is the first major case-control study to simultaneously address all currently hypothesized causes of NGU.

6 Jan 2006

Rotateq eliminates the most severe cases of rotavirus

In a study of more than 68,000 infants published in the New England Journal of Medicine, the investigational vaccine Rotateq demonstrated that it can safely prevent 98 percent of severe cases of viral diarrhea and vomiting that account for 2 million hospital visits and 500,000 pediatric deaths each year worldwide.

6 Jan 2006

Molecular finding will help better understand measles and mumps

A team of Northwestern University researchers has solved the structure of a molecule that controls the ability of viruses of the paramyxovirus family, including the viruses that cause measles, mumps, and many human respiratory diseases, to fuse with and infect human cells.

5 Jan 2006

MRSA prevalence may be due to over-prescribing and overuse of antibiotics

A dangerous drug-resistant bacterium is becoming more prevalent in many intensive care units, according to an article in the Feb. 1 issue of Clinical Infectious Diseases, now available online.

5 Jan 2006

Clarithromycin reduces recurrent cardiovascular events in patients without periodontitis

Periodontitis, an infection of the gingiva and tooth-supporting tissues, may influence the effectiveness of antibiotics used for the prevention of recurrent cardiovascular events.

5 Jan 2006

New drug shows promise in fighting Tuberculosis (TB)

Scientists from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, have determined how a promising drug candidate attacks the bacterium that causes tuberculosis (TB). Published online this week in Proceedings of the National Academy of Sciences, the finding may help scientists optimize the drug candidate, PA-824, which targets Mycobacterium tuberculosis (M. tb).

28 Dec 2005

New drug shows promise in fighting Tuberculosis (TB)

28 Dec 2005

Childhood infections stunt growth and reduce life expectancy

Records from four European countries show that, on average, survivors of generations with rampant childhood infection - measured by cohort mortality rates at young ages - were shorter and died sooner than counterparts from generations with less childhood disease.

28 Dec 2005

Extremely infectious pneumonia-like disease slips through body's immune system

A new study found that an extremely infectious pneumonia-like disease in humans slips through the immune system's usual defense mechanisms.

21 Dec 2005

2 million people carry drug-resistant bacteria in their noses

New research estimates that about 2 million people carry a strain of drug-resistant bacteria in their noses.

21 Dec 2005

New understanding of Mediterranean spotted fever

New research by a team of scientists in France and the United States has identified both the bacterial and host receptor proteins that enable Rickettsia conorii, the Mediterranean spotted fever pathogen, to enter cells.

15 Dec 2005

Scientists working to protect us against avian and pandemic flu

The expression 'prevention is better than a cure' is a truism when it comes to vaccine research. European scientists in various EU-funded projects are hard at work developing new vaccines, treatments and diagnostic tools against some of the deadliest and most virulent viruses, including strains of avian flu.

15 Dec 2005

Streptococcus mutans copes without pathway

Leave it to the bacteria that cause tooth decay to be able to live without something all cells were thought to require.

13 Dec 2005

Disaster or pandemic - U.S. needs to get real!

According to a report by the organization Trust for America's Health (TFAH), hospitals in the U.S. are not properly prepared to handle patients who would arrive after a disaster or a pandemic.

7 Dec 2005

Inexpensive blood test for major parasitic diseases

The National Reference Centre for Parasitology (NRCP), based at the MUHC, is developing a comprehensive and inexpensive blood safety test that will allow clinicians to check for all major parasitic diseases in patients' blood.

5 Dec 2005

Contact with pigs increases risk of animal flu viruses

Farmers, veterinarians and meat processors who routinely come into contact with pigs in their jobs have a markedly increased risk of infection with flu viruses that infect pigs, according to a study funded in part by the National Institute of Allergy and Infectious Diseases (NIAID).

28 Nov 2005

Caring for our Children

A new Cincinnati Children's Hospital Medical Center study shows that parents, pediatricians and child care providers are equally unknowledgeable about guidelines that recommend whether children should be excluded from child care due to particular illnesses.

28 Nov 2005

Emerging infectious diseases will get worse

Emerging infectious diseases pose a global threat to human and animal health, and the problem is likely to worsen, warns an expert in the British Medical Journal (BMJ).

26 Nov 2005