Liver News and Research

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Biological breakthrough that could offer new hope in the fight against liver cancer

Professor John Mayer and Dr Simon Dawson, in collaboration with colleagues at Japan's Kyoto University, have discovered the function of a new liver oncoprotein - or cancer causing protein - which could be the first step to finding effective new treatments for the deadly illness.

21 Jul 2005

Protein found in fat cells is a newly discovered cause of insulin resistance

A study led by researchers at Beth Israel Deaconess Medical Center (BIDMC) has shown that a protein found in fat cells is a newly discovered cause of insulin resistance, establishing a previously unidentified molecular link between obesity and type 2 diabetes and offering a potential new target for the development of drugs to treat diabetes.

20 Jul 2005

Alendronate combined with calcium and vitamin D almost completely prevented further bone loss in the first 4 months afte liver transplant

A new study found that the drug used to treat osteoporosis, when used in combination with calcium and vitamin D, can prevent the additional bone loss that commonly occurs after liver transplants. The treatment also helped stabilize bone loss in patients who already had osteoporosis, and helped improve their bone mineral density (BMD).

20 Jul 2005

Metformin should be in the first line of defense against type 2 diabetes

A new review of studies confirms that the drug metformin should be in the first line of defense against type 2 diabetes. Using metformin alone can improve control of blood glucose, while also reducing risk factors for heart disease such as excess body weight, cholesterol levels and hypertension, the review found.

20 Jul 2005

Combination of ribavirin and interferon is more effective in treating hepatitis C than using interferon alone

The researchers reviewed 72 randomized trials and 9,991 patients who had chronic hepatitis C for more than six months and were previously untreated, who had relapsed after treatment or who had not responded to other treatment.

19 Jul 2005

Insulin keeps fat in the liver under control

Insulin, a hormone long recognized as a generator of fat, also keeps fat in the liver under control, according to a new study in the July issue of Cell Metabolism.

19 Jul 2005

A study analyzes the most important factors leading to death or liver transplant in drug-induced liver disease

Drug-induced liver disease (DILD), a potential complication seen with some medications, is usually not life-threatening, but may occasionally be more severe with a high mortality, requiring a liver transplant in selected cases.

18 Jul 2005

New treatment option for bad breath

More than 90 million Americans can sigh comfortably because of new relief for their bad breath. Dental experts today revealed research highlighting a new treatment option that can eliminate halitosis or chronic bad breath at the Academy of General Dentistry's (AGD) 53rd Annual Meeting in Washington, D.C.

18 Jul 2005

New molecular insights may one day lead to opportunities to stave off old age

Delving deep into the molecular subtleties of a strain of mice engineered to age rapidly, scientists have found that an accumulation of genetic mutations prompts a cascade of programmed cell death that seems to underpin the aging process.

18 Jul 2005

Scientists sequence the genomes of three species of parasites responsible for causing diseases that kill or cripple millions

Howard Hughes Medical Institute (HHMI) scientists who participated in the project say the sequencing of the genomes of the parasitic protozoa that cause Chagas disease, African sleeping sickness, and leishmaniasis, could significantly impact world health. Some of the genes discovered may prove to be good drug and vaccine targets.

17 Jul 2005

Complicated plasminogen system yields potential therapeutic target; Implications for aging and degenerative diseases

Skeletal muscles naturally repair themselves very efficiently after injury. But when they don’t, otherwise successful recovery following damage from overuse during exercise, surgery or trauma can be stymied. Furthermore, as we age, muscle repair slows noticeably, and in Duchenne Muscular Dystrophy and other degenerative muscle diseases, normal repair functions can’t cope with disease progression.

14 Jul 2005

Targeted program drastically reduced hepatitis A in U.S.

According to a newly released study, the number of cases of hepatitis A have fallen by 76 percent in the United States since a vaccination campaign targeted children in communities with the highest rates of the disease.

13 Jul 2005

Patients suffering from oral cancer have increased levels of certain bacteria in their saliva

Six common species of bacteria were found at significantly higher levels in the saliva of patients with oral squamous cell carcinoma (OSCC) than in the saliva of healthy individuals.

6 Jul 2005

Ten million Africans treated by international disease treatment

A disease treatment programme started three years ago by Imperial College London has now treated over ten million African children and adults for schistosomiasis and intestinal worm infections in six sub-Saharan countries.

6 Jul 2005

Showering in manganese-contaminated water could have permanent effects on the nervous system

A new analysis based on animal studies suggests that showering in manganese-contaminated water for a decade or more could have permanent effects on the nervous system. The damage may occur even at levels of manganese considered safe by the Environmental Protection Agency, according to researchers from Wake Forest University School of Medicine.

6 Jul 2005

New study shows showering in manganese contaminated water could permanently affect the nervous system

1 Jul 2005

Cordis release new stent featuring the latest advancement in balloon-expandable stent technology

Cordis Endovascular, today announced the U.S. launch of the PALMAZ(R) BLUE(TM) Transhepatic Biliary Cobalt Chromium Stent, the latest advancement in balloon-expandable stent technology. Featuring L605, a cobalt alloy enhanced with tungsten, the PALMAZ(R) BLUE(TM) Stent is stronger than stainless steel stents and uses less metal.

1 Jul 2005

Liver News and Research

Biological breakthrough that could offer new hope in the fight against liver cancer

Protein found in fat cells is a newly discovered cause of insulin resistance

Alendronate combined with calcium and vitamin D almost completely prevented further bone loss in the first 4 months afte liver transplant

Metformin should be in the first line of defense against type 2 diabetes

Combination of ribavirin and interferon is more effective in treating hepatitis C than using interferon alone

Insulin keeps fat in the liver under control

A study analyzes the most important factors leading to death or liver transplant in drug-induced liver disease

New treatment option for bad breath

New molecular insights may one day lead to opportunities to stave off old age

Scientists sequence the genomes of three species of parasites responsible for causing diseases that kill or cripple millions

Complicated plasminogen system yields potential therapeutic target; Implications for aging and degenerative diseases

Targeted program drastically reduced hepatitis A in U.S.

Patients suffering from oral cancer have increased levels of certain bacteria in their saliva

Ten million Africans treated by international disease treatment

Showering in manganese-contaminated water could have permanent effects on the nervous system

New study shows showering in manganese contaminated water could permanently affect the nervous system

Cordis release new stent featuring the latest advancement in balloon-expandable stent technology

Studies compare hepatitis B drugs

Map of gene control regions provides tool for understanding cells' different roles

Exercise helps find genetic regions linked to prediabetes

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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