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Targeting cholesterol metabolism in eye may prevent age-related macular degeneration, says study

Targeting cholesterol metabolism in the eye might help prevent a severe form of age-related macular degeneration (AMD), one of the most common causes of blindness in older Americans, according to indications in a study in mice, which was supported by the National Institutes of Health.

3 Apr 2013

CRG researchers reprogramme lymphoma and leukaemia cells to halt malignancy

Researchers from the Centre for Genomic Regulation (CRG) in Barcelona reprogramme lymphoma and leukaemia cells to halt their malignancy. Resulting cells remain benign even when no longer subjected to treatment and reduce likelihood of developing new tumours.

3 Apr 2013

Ulcerative colitis and Crohn’s disease treatments: an interview with Dr Parikh, vice president, general medicine, Takeda

Ulcerative colitis (UC) and Crohn’s disease (CD) are both relapsing and remitting chronic diseases of bowel inflammation. By that I mean they flare and physicians try to get the flare under control and try to induce remission. However, despite a number of treatments available, they tend to relapse.

From Takeda 3 Apr 2013

First Edition: April 3, 2013

Today's headlines include reports about how the latest round of payment rates for private Medicare plans led to stock market gains for insurers.

3 Apr 2013

UAB School of Nursing offers health care services in rural communities

"If individuals, families, and communities don't have access, then they don't have the opportunity for a better life," asserts University of Alabama at Birmingham School of Nursing Dean Doreen C. Harper, PhD, RN, FAAN.

3 Apr 2013

Research findings shed light on how neurons translate sensory input into actions

New research by scientists at the University of Massachusetts Medical School shows at the single cell level how an external stimulus sets off a molecular chain reaction in the transparent roundworm C. elegans, a process in which a single neurotransmitter coordinates and times two separate actions.

3 Apr 2013

New report on Western European Health Information Exchange Market

The European market for health information exchange is diverse, with different IT vendors supporting the process of information exchange at different levels. European healthcare policies favour interoperability. This is encouraging the growth of public health information exchange programmes.

3 Apr 2013

BIND Therapeutics and Pfizer sign collaboration agreement to develop, commercialize Accurins

BIND Therapeutics, a clinical-stage biopharmaceutical company developing a new class of highly selective targeted and programmable therapeutics called Accurins, announced today that it has entered into a global collaboration agreement with Pfizer Inc. to develop and commercialize Accurins utilizing select small molecule targeted therapies.

3 Apr 2013

New report addresses presence of cerebral abnormalities in eating disorders

A report from the University of Freiburg that is published in one of the last issue of Psychotherapy and Psychosomatics address the presence of cerebral abnormalities in eating disorders.

3 Apr 2013

PARP inhibitors can be novel treatment strategy for cisplatin-resistant cancer

Poly (ADP-ribose) polymerase inhibitors may be a novel treatment strategy for patients with cancer that has become resistant to the commonly used chemotherapy drug cisplatin, according to data from a preclinical study published in Cancer Research, a journal of the American Association for Cancer Research.

3 Apr 2013

Washington Post examines how mobile technologies are transforming remote parts of Africa

The Washington Post examines how new mobile applications are transforming remote parts of Africa.

3 Apr 2013

Study suggests gay men in Mexico City willing to participate in HIV prevention activities for $288 per year

"A new study suggests that most young gay men in Mexico City would pledge to stay HIV-free, attend a monthly safe-sex talk and take regular HIV tests to prove they were uninfected -- all in return for just $288 a year," the New York Times reports.

3 Apr 2013

'Remarkable alignment' of PEPFAR, Global Fund efforts is reason for continued support

Recent global health events -- including the release of PEPFAR's Blueprint for an AIDS-Free Generation (.pdf), the launch of the Global Fund to Fight AIDS, Tuberculosis and Malaria's new funding model, and the Institute of Medicine's evaluation of PEPFAR -- "mak[e] it clear; it is a time of transformation for global health," Deborah Derrick, president of the Friends of the Global Fight Against HIV, Tuberculosis and Malaria, writes in the Huffington Post's "The Big Push" blog.

3 Apr 2013

UAB School of Nursing raising bar on service for veterans

Partnering with Birmingham's VA Medical Center and with colleagues across a wide range of health care professions, the University of Alabama at Birmingham School of Nursing is raising the bar on service for veterans and their families.

3 Apr 2013

President Obama meets with 4 African leaders to discuss range of development issues

"President Obama met on Thursday with the leaders of four small countries in sub-Saharan Africa that the White House sees as models for the region," including "Ernest Bai Koroma, president of Sierra Leone; Macky Sall, president of Senegal; Joyce Banda, president of Malawi; and Jose Maria Pereira Neves, prime minister of Cape Verde," the Washington Post reports (Goldfarb, 3/28).

3 Apr 2013

U.S. agencies supporting fight against HIV/AIDS in Malawi

"U.S. agencies that work to fight HIV this week began a five-year effort with Malawi's government to improve health care for Malawians infected with the virus," VOA News reports.

3 Apr 2013

Policymakers should help improve food security in urban areas, report says

"Tackling hunger is not only a question of producing more food in rural areas, but requires looking at why poor urban populations struggle to eat enough -- a problem aggravated by climate change, a report from the International Institute for Environment and Development said on Thursday," AlertNet reports.

3 Apr 2013

Sanford-Burnham selects organizations to participate in Florida Translational Research Program

Sanford-Burnham Medical Research Institute at Lake Nona announced the selection of the first five research organizations that will participate in the Florida Translational Research Program to advance drug discovery in the state.

3 Apr 2013

NTDs have 'devastating consequences' for 1 out of 6 people worldwide

"There are so many things we take for granted in America. One of them is that our children are not regularly infected by one of the tropical diseases so common among the world's poorest people," Richard Besser, ABC News' chief health and medical editor, writes in an ABC News opinion piece.

3 Apr 2013

Imbalance between neutrophil elastase and α1-antitrypsin leads to obesity, inflammation

Many recent studies have suggested that obesity is associated with chronic inflammation in fat tissues. Researchers at Sanford-Burnham Medical Research Institute have discovered that an imbalance between an enzyme called neutrophil elastase and its inhibitor causes inflammation, obesity, insulin resistance, and fatty liver disease.

3 Apr 2013

Research News and Research

Targeting cholesterol metabolism in eye may prevent age-related macular degeneration, says study

CRG researchers reprogramme lymphoma and leukaemia cells to halt malignancy

Ulcerative colitis and Crohn’s disease treatments: an interview with Dr Parikh, vice president, general medicine, Takeda

First Edition: April 3, 2013

UAB School of Nursing offers health care services in rural communities

Research findings shed light on how neurons translate sensory input into actions

New report on Western European Health Information Exchange Market

BIND Therapeutics and Pfizer sign collaboration agreement to develop, commercialize Accurins

New report addresses presence of cerebral abnormalities in eating disorders

PARP inhibitors can be novel treatment strategy for cisplatin-resistant cancer

Washington Post examines how mobile technologies are transforming remote parts of Africa

Study suggests gay men in Mexico City willing to participate in HIV prevention activities for $288 per year

'Remarkable alignment' of PEPFAR, Global Fund efforts is reason for continued support

UAB School of Nursing raising bar on service for veterans

President Obama meets with 4 African leaders to discuss range of development issues

U.S. agencies supporting fight against HIV/AIDS in Malawi

Policymakers should help improve food security in urban areas, report says

Sanford-Burnham selects organizations to participate in Florida Translational Research Program

NTDs have 'devastating consequences' for 1 out of 6 people worldwide

Imbalance between neutrophil elastase and α1-antitrypsin leads to obesity, inflammation

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

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Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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How Omics Technologies Are Transforming Biological Research and Drug Discovery