Infectious Diseases News and Research

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First large-scale bird flu genome study

Investigators at St. Jude Children's Research Hospital have completed the first large-scale study of bird flu virus genomes, thereby doubling the amount of genetic information available on the genes and proteins of these viruses.

26 Jan 2006

Study estimates 500,000 fatalities from bird flu pandemic outbreak in Japan

Risk Management Solutions, Inc. (RMS) released the findings of an in-depth study that provides life and personal accident insurers in Japan with key benchmarks for the potential risk of human casualties from catastrophic events.

26 Jan 2006

Identity Swap: Finding the variants that human history has favoured

Sequence differences in less than 0.2% of the 3-billion-base human genome play a vital role in a bewildering variety of human disease. Researchers from the Wellcome Trust Sanger Institute and the Cambridge University’s Cambridge Institute for Medical Research, together with international colleagues report in PLoS Genetics their detailed maps of differences implicated in disease as well as genes that are unchanged in recent human history.

26 Jan 2006

Follow the money trail to track the disease

It seems that a popular Web site in the United States that tracks the geographical circulation of money could cast new light on predicting where infectious diseases like bird flu might pop up.

26 Jan 2006

Injection no better than a placebo at preventing influenza in children

U.S. health authorities should have waited for more evidence before recommending routine flu shots for healthy toddlers, according to a new systematic review of studies involving half a million children worldwide.

25 Jan 2006

Breakthrough in lupus research

A major breakthrough in lupus research - one that may fundamentally change thinking on how the disease affects behavior and cognition - was reported in the January 17, 2006 Proceedings of the National Academy of Sciences (PNAS).

25 Jan 2006

Avian influenza could have disastrous effects on countries' economies, infrastructures, populations, public health and stability

In the past, when government leaders, policymakers and scholars have turned their attention to peace and security issues, the talk invariably has focused on war, arms control or anti-terrorism strategies. But Julian Palmore believes it's time to expand the scope of the conversation.

25 Jan 2006

Guidelines for International Breast Health and Cancer Control

Specific recommendations for improving breast-health care and cancer treatment in countries with limited resources have been published by the Breast Health Global Initiative (BHGI), an international coalition of doctors, scientists, policy makers and advocates led by Fred Hutchinson Cancer Research Center and the Susan G. Komen Breast Cancer Foundation.

25 Jan 2006

Morphotek issued patent covering the use of chemical inhibitors of mismatch repair

Morphotek Inc. announced today the issuance of United States Patent 6,982,169 covering the use of chemical inhibitors to enhance evolution of target host cell genomes by reversibly regulating mismatch repair (MMR) in vivo.

23 Jan 2006

Preparing for bird flu

When a new strain of flu infects people, the infection can spread around the world quickly. This is what could potentially happen with some new human flu viruses that come from bird flu viruses.

18 Jan 2006

Genetic risk factor for West Nile virus infection identified

People who lack a cell surface protein called CCR5 are highly resistant to infection by HIV but may be at increased risk of developing West Nile virus (WNV) illness when exposed to the mosquito-borne virus, report researchers from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH).

18 Jan 2006

Flu - not the only germ threat this time of year!

The flu hasn't even hit hard yet this year, but it seems like everyone's getting sick. What's the deal?

16 Jan 2006

Vaccine candidate for hepatitis C

Researchers at the University of Saskatchewan's Vaccine and Infectious Disease Organization (VIDO) have developed a vaccine candidate for hepatitis C, leading to hope in the fight against a disease for which no vaccines are yet available.

11 Jan 2006

Tobacco plant-derived vaccines safeguard against Yersinia pestis

Through an innovative feat of plant biotechnology and vaccine design, researchers in the Biodesign Institute at Arizona State University have successfully turned tobacco plants into vaccine production factories to combat the deadliest form

10 Jan 2006

Genetic mutation that protects against HIV increases the risk of West Nile Virus infection

A genetic mutation that protects against HIV increases the risk of developing clinical West Nile Virus infection, according to a new study appearing online on January 9th in The Journal of Experimental Medicine.

9 Jan 2006

Data establishes safety profile of new GlaxoSmithKline rotavirus vaccine candidate

Data from one of the largest infant vaccine trials ever conducted, published in the New England Journal of Medicine (NEJM), showed GlaxoSmithKline's (GSK) rotavirus vaccine candidate as effective against rotavirus disease (rotavirus gastroenteritis) in the first year of life. Rotavirus is the leading recognized cause of diarrhea-related illness and death among infants and young children.

6 Jan 2006

Risk factors for nongonococcal urethritis

The study, by Australian researchers Catriona Bradshaw, MD, and colleagues at the Melbourne Sexual Health Centre, is the first major case-control study to simultaneously address all currently hypothesized causes of NGU.

6 Jan 2006

Rotateq eliminates the most severe cases of rotavirus

In a study of more than 68,000 infants published in the New England Journal of Medicine, the investigational vaccine Rotateq demonstrated that it can safely prevent 98 percent of severe cases of viral diarrhea and vomiting that account for 2 million hospital visits and 500,000 pediatric deaths each year worldwide.

6 Jan 2006

Molecular finding will help better understand measles and mumps

A team of Northwestern University researchers has solved the structure of a molecule that controls the ability of viruses of the paramyxovirus family, including the viruses that cause measles, mumps, and many human respiratory diseases, to fuse with and infect human cells.

5 Jan 2006

MRSA prevalence may be due to over-prescribing and overuse of antibiotics

A dangerous drug-resistant bacterium is becoming more prevalent in many intensive care units, according to an article in the Feb. 1 issue of Clinical Infectious Diseases, now available online.

5 Jan 2006