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Characterization of the baseline SARS-CoV-2 S-reactive B cell repertoire

Researchers from the University Of Amsterdam have identified several oddities in unvaccinated individuals' antibody response to the spike protein.

8 Dec 2021

Study identifies ORF8 protein as a key COVID-19 causing factor

New study suggests that the SARS-CoV-2 ORF8 protein is the underlying cause behind severe COVID-19 infection.

8 Dec 2021

Interactions between RNA viruses and human RNA-binding proteins

During the virus's attempt to use the host cell to replicate, host proteins interact heavily with the viral genome. Researchers have been investigating these interactions.

8 Dec 2021

Equilibrium simulation of SARS-CoV-2 spike protein highlights its global conformational characteristics

A team of researchers set out to build a full-length, membrane-embedded spike to study its conformational dynamics at the atomic level using molecular dynamics simulations to understand better how this important component of the virus machinery works.

8 Dec 2021

Breastmilk T cell repertoire is enriched for SARS-CoV-2 Spike-specificity after maternal mRNA vaccination

New study demonstrates that it is possible one day that breastmilk samples will be used to characterize broad mucosal immunity after vaccination.

8 Dec 2021

Quantum mechanical characterization of SARS-CoV-2 Omicron variant interaction with human ACE2 receptor

Researchers from Universite Grenoble Alpes have been investigating the changes in the Omicron variant RBD and how they affect ACE2 binding.

8 Dec 2021

Does a COVID-19 vaccine booster improve the immune response of a poor responder?

A new study has focussed on determining the levels of nAb in individuals who received the second and third doses of the RNA vaccines developed by Pfizer and Moderna.

8 Dec 2021

Olympus scanR high-content screening station v. 3.3 adds improved deep-learning capabilities for fast, efficient image analysis

The scanR high-content screening station provides fully automated image acquisition and data analysis. Version 3.3 improves the deep-learning technology’s capabilities to reliably separate objects in biological samples using instance segmentation, the ability to detect and delineate distinct objects of interest in an image.

From Evident Corporation - Life Sciences 8 Dec 2021

Canopy Biosciences launches the first of a series of targeted assay kits for ChipCytometry

Canopy Biosciences, a Bruker Company, today announced the launch of a first in a series of assay kits for ChipCytometry, a quantitative, high dynamic range and high-resolution multiplexing technology for spatial proteomics.

From Bruker Nano Surfaces and Metrology 8 Dec 2021

Study analyzes the contribution of AI to cancer patient care and vaccine design

Artificial Intelligence/Machine Learning (AI/ML) is the development of computer systems that are able to perform tasks that would normally require human intelligence. AI/ML is used by people every day, for example, while using smart home devices or digital voice assistants.

8 Dec 2021

Researchers uncover the journey of microglia in developing zebrafish

Microglia, the immune cells of the brain, form the first line of defense against neurodegenerative diseases and traumatic brain injuries.

8 Dec 2021

Epigenetic clocks have potential as biomarkers of COVID-19 vaccine responses

New findings have important implications for research into the impact of COVID-19 and the mRNA vaccination on epigenetic aging in the immune system.

7 Dec 2021

The antiviral potential of 4′-fluorouridine as an oral treatment against RSV and SARS-CoV-2

New research reports 4’-Fluorouridine (4′-FlU) as an oral antiviral against RSV and SARS-CoV-2.

7 Dec 2021

An assessment of pH-sensitive cationic lipid nanoparticles for drug delivery

A recent review looks at the molecular design of pH-sensitive cationic lipids and their applications for various tissues and cell types.

7 Dec 2021

SARS-CoV-2 Delta variant changes receptor binding domain conformation to escape host antibodies

Researchers investigate the conformational dynamics of the SARS-CoV-2 RBD using the atomistic molecular dynamics simulation method.

7 Dec 2021

Scientists find new way to reverse aggressive breast cancer into a less dangerous kind

Scientists at KAIST believe they may have found a way to reverse an aggressive, treatment-resistant type of breast cancer into a less dangerous kind that responds well to treatment.

7 Dec 2021

Research reveals a common cause for seizures and memory problems in epilepsy

Damage to a part of the brain that regulates hyperactivity can contribute to both memory problems and seizures in the most common form of epilepsy, according to research at the University of Wisconsin–Madison.

7 Dec 2021

Hypercoagulability of the blood responsible for cardiac thrombosis in COVID-19 patients

Researchers examined autopsy tissue samples of hearts from patients who died early in the COVID-19 pandemic.

7 Dec 2021

A promising new therapeutic target for kidney disease

Despite nearly two million people dying of acute kidney injury every year, and tens of millions more needing treatment, no effective drug treatment for the condition is available.

7 Dec 2021

New approach to enhance the therapeutic efficacy of liver cancer immunotherapy

In recent years, tumor immunotherapy has emerged as a highly promising and much-touted oncological approach.

7 Dec 2021

B Cell News and Research

Characterization of the baseline SARS-CoV-2 S-reactive B cell repertoire

Study identifies ORF8 protein as a key COVID-19 causing factor

Interactions between RNA viruses and human RNA-binding proteins

Equilibrium simulation of SARS-CoV-2 spike protein highlights its global conformational characteristics

Breastmilk T cell repertoire is enriched for SARS-CoV-2 Spike-specificity after maternal mRNA vaccination

Quantum mechanical characterization of SARS-CoV-2 Omicron variant interaction with human ACE2 receptor

Does a COVID-19 vaccine booster improve the immune response of a poor responder?

Olympus scanR high-content screening station v. 3.3 adds improved deep-learning capabilities for fast, efficient image analysis

Canopy Biosciences launches the first of a series of targeted assay kits for ChipCytometry

Study analyzes the contribution of AI to cancer patient care and vaccine design

Researchers uncover the journey of microglia in developing zebrafish

Epigenetic clocks have potential as biomarkers of COVID-19 vaccine responses

The antiviral potential of 4′-fluorouridine as an oral treatment against RSV and SARS-CoV-2

An assessment of pH-sensitive cationic lipid nanoparticles for drug delivery

SARS-CoV-2 Delta variant changes receptor binding domain conformation to escape host antibodies

Scientists find new way to reverse aggressive breast cancer into a less dangerous kind

Research reveals a common cause for seizures and memory problems in epilepsy

Hypercoagulability of the blood responsible for cardiac thrombosis in COVID-19 patients

A promising new therapeutic target for kidney disease

New approach to enhance the therapeutic efficacy of liver cancer immunotherapy

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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