Receptor News and Research

RSS

Stem cell research updates

Two studies have been published this Wednesday in the journal Nature that show that work remains before so-called induced pluripotent stem (iPS) cells are ready for use in laboratory studies or clinical therapies. These iPS cells are body cells that are programmed to unwind back into an embryonic state. Like embryonic stem cells, they have potential to develop into any other type of cell in the body. However researchers are showing that these cells do not reprogram perfectly.

3 Mar 2011

New research provides insight into link between sunlight, vitamin D3, MS risk and severity

New research into the neurodegenerative disease, Multiple Sclerosis offers new insight into the link between sunlight, vitamin D3, and MS risk and severity.

3 Mar 2011

Scientists discover genetic process that may allow ovarian cancer to resist chemotherapy

York University researchers have zeroed in on a genetic process that may allow ovarian cancer to resist chemotherapy.

3 Mar 2011

Omeros identifies orphan GPCR compounds associated to pancreatic cancer, cognitive disorders

Omeros Corporation today announced that it has identified compounds that interact selectively with two orphan G protein-coupled receptors linked to pancreatic cancer and cognitive disorders.

3 Mar 2011

U-M scientists identify potential target to treat aggressive prostate cancer

Researchers at the University of Michigan Comprehensive Cancer Center have identified a potential target to treat an aggressive type of prostate cancer. The target, a gene called SPINK1, could be to prostate cancer what HER2 has become for breast cancer.

3 Mar 2011

FADD protein discovery can lead to better cancer and autoimmune disease drugs

Reporting in Nature, scientists from Thomas Jefferson University have determined that a single protein called FADD controls multiple cell death pathways, a discovery that could lead to better, more targeted autoimmune disease and cancer drugs.

3 Mar 2011

Ibuprofen may protect against development of Parkinson's disease

New research suggests that ibuprofen may offer protection against developing Parkinson's disease, according to one of the largest studies to date investigating the possible benefits of the over-the-counter drug on the disease. The study is published in the March 2, 2011, online issue of Neurology®, the medical journal of the American Academy of Neurology.

2 Mar 2011

Virostatics' VS411 Phase 2a trial results against HIV presented at 18th CROI

An analysis of immune markers measured in a sub-study of ViroStatics' proof-of-concept Phase 2a trial showed that VS411 was able to reduce immune activation while producing a median 1.5 log10 reduction in viral load.

2 Mar 2011

Genetic switch increases blood vessels in skeletal muscle of non-exercising mice

Many people suffer from a devastating condition known as critical limb ischemia (CLI) that can lead to muscle wasting and even amputation. The disease is linked to the blockage of blood flow to the skeletal muscle and current treatment options include rehabilitative exercise and surgical bypass of blood vessels. New preclinical research suggests there may be a way to restore blood supply in skeletal muscle without traditional intervention.

2 Mar 2011

NCI sponsors multi-center phase 2 study of entinostat-anastrozole combination in triple negative breast cancer

Syndax Pharmaceuticals, a clinical-stage epigenetics oncology company, announced the National Cancer Institute (NCI) will sponsor a multi-center phase 2 study of Syndax's lead product entinostat, a novel inhibitor of histone deacetylases (HDAC), and anastrozole, an aromatase inhibitor, in postmenopausal women with operable triple negative breast cancer to evaluate biomarkers and surrogates for response.

2 Mar 2011

Study confirms risk of triple-negative breast cancer among obese, physically inactive women

New findings published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research, confirm the risk of breast cancer among women who are obese and not physically active, and suggests additional mechanisms beyond estrogen.

1 Mar 2011

Bayhill's BHT-3034 receives FDA IND clearance for treatment of myasthenia gravis

Bayhill Therapeutics Inc, a clinical-stage biopharmaceutical company utilizing its proprietary BHT-DNA™ platform to develop novel and targeted autoimmune and immune-mediated disease treatments, today announced the successful clearance of an IND with the US FDA for BHT-3034, a disease-modifying DNA plasmid vaccine immunotherapy for patients with the autoimmune neuromuscular junction disease myasthenia gravis.

1 Mar 2011

New research reveals how maternal antibodies block immune response to measles virus

New research that reveals how maternal antibodies block an immune response to the measles virus is a first step toward improving current childhood vaccination practices, scientists say.

1 Mar 2011

Leptin receptor antagonist peptide demonstrates efficacy against triple negative breast cancer

A new peptide developed by researchers in Temple University's College of Science and Technology has demonstrated efficacy against triple negative breast cancer.

1 Mar 2011

Positive preliminary data from SB-728-902 Phase 1 trial against HIV/AIDS presented at 18th CROI

Sangamo BioSciences, Inc. announced today the presentation of positive preliminary clinical data from its Phase 1 trial.

1 Mar 2011

Two genes linked to binge drinking

University of Maryland School of Medicine researchers have identified two genes associated with binge drinking that may open doors to new, more effective treatments for excessive alcohol drinking. The scientists found that manipulating two receptors in the brain, GABA receptors and toll-like receptor 4 (TLR4), "caused profound reduction" of binge drinking for two weeks in rodents that had been bred and trained to drink excessively. The study was published online the week of Feb. 28 in the journal the Proceedings of the National Academy of Sciences.

1 Mar 2011

First study to show link between AVPR1A gene variants with listening to music

Music is listened in all known cultures. Similarities between human and animal song have been detected: both contain a message, an intention that reflects innate emotional state that is interpreted correctly even among different species.

28 Feb 2011

Researchers identify gene behind self-healing skin cancer

Cancer Research UK scientists have discovered the gene behind a rare skin cancer which grows rapidly for a few weeks before healing spontaneously, according to research published in Nature Genetics.

28 Feb 2011

Takeda receives FDA approval for EDARBI to treat hypertension in adults

Takeda Pharmaceutical Company Limited and its wholly-owned subsidiary, Takeda Pharmaceuticals North America, Inc., today announced that the U.S. Food and Drug Administration approved EDARBI for the treatment of hypertension, or high blood pressure, in adults.

27 Feb 2011

Researchers explain genetic differences that distinguish early-transmitting HIVs-viruses

A new finding from scientists at the National Institutes of Health could help efforts to design vaccines and other prevention tools to block HIV in the early stages of sexual transmission, before infection takes hold. Researchers at the NIH National Institute of Allergy and Infectious Diseases have helped explain genetic differences that can distinguish some early-transmitting HIVs-viruses found in an infected individual within the first month after infection-from forms of HIV isolated later in infection.

25 Feb 2011

Receptor News and Research

Stem cell research updates

New research provides insight into link between sunlight, vitamin D3, MS risk and severity

Scientists discover genetic process that may allow ovarian cancer to resist chemotherapy

Omeros identifies orphan GPCR compounds associated to pancreatic cancer, cognitive disorders

U-M scientists identify potential target to treat aggressive prostate cancer

FADD protein discovery can lead to better cancer and autoimmune disease drugs

Ibuprofen may protect against development of Parkinson's disease

Virostatics' VS411 Phase 2a trial results against HIV presented at 18th CROI

Genetic switch increases blood vessels in skeletal muscle of non-exercising mice

NCI sponsors multi-center phase 2 study of entinostat-anastrozole combination in triple negative breast cancer

Study confirms risk of triple-negative breast cancer among obese, physically inactive women

Bayhill's BHT-3034 receives FDA IND clearance for treatment of myasthenia gravis

New research reveals how maternal antibodies block immune response to measles virus

Leptin receptor antagonist peptide demonstrates efficacy against triple negative breast cancer

Positive preliminary data from SB-728-902 Phase 1 trial against HIV/AIDS presented at 18th CROI

Two genes linked to binge drinking

First study to show link between AVPR1A gene variants with listening to music

Researchers identify gene behind self-healing skin cancer

Takeda receives FDA approval for EDARBI to treat hypertension in adults

Researchers explain genetic differences that distinguish early-transmitting HIVs-viruses

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Latest News