Protein C News and Research

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Researchers discover rare genetic disorder that affects the brain, heart and facial features

Researchers at the National Institutes of Health have discovered a new genetic disorder characterized by developmental delays and malformations of the brain, heart and facial features.

20 Jan 2021

Automated method tracks cortical origin and initial spread of TAU proteins in Alzheimer’s disease

Researchers have developed an automated method that can track the development of harmful clumps of TAU protein related to Alzheimer's disease in the brain, according to work involving 443 individuals.

20 Jan 2021

Eliminating key gene could revive exhausted immune cells to battle solid tumors

Eliminating a single gene can turn exhausted cancer-fighting immune cells known as CD8+ T cells back into refreshed soldiers that can continue to battle malignant tumors, a new study led by UT Southwestern researchers suggests.

20 Jan 2021

COVID-19 has transformed the world of vaccines

Researchers at GlaxoSmithKline (GSK) in Italy and Belgium say the coronavirus disease 2019 (COVID-19) pandemic is transforming the world of vaccinology by accelerating vaccine development and the availability of powerful technologies.

20 Jan 2021

South African SARS-CoV-2 variant escapes antibody neutralization

Researchers in South Africa have conducted a study showing that the novel 501Y.V2 variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that has emerged in the country is able to escape the neutralizing antibodies that are elicited by previously circulating strains of the virus.

20 Jan 2021

Ethacrynic acid, a diuretic drug with potential anti-SARS-CoV-2 activity

A study published recently in the journal Viruses has identified a potent diuretic ethacrynic acid as an efficient inhibitor of the main protease of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This drug can be potentially repurposed to treat coronavirus disease 2019 (COVID-19).

20 Jan 2021

Researchers develop new method for charting SARS-CoV-2 spike protein glycosylation

Researchers develop a novel, simple and affordable method for N-glycan fingerprinting based on enzymatic fluorescent glycan labeling and electrophoresis. This new method may help us understand important changes in glycosylation in the SARS-CoV-2 spike protein – something which could inform future therapeutic research.

20 Jan 2021

BMP5/7 protein offers promising therapeutics that could halt the progression of Parkinson's disease

Ben-Gurion University of the Negev researchers have discovered that the protein BMP5/7 offers promising therapeutics that could slow down or halt the progression of Parkinson's disease.

20 Jan 2021

Study shows that single water molecule may cause antibiotic resistance

New high-resolution structures of the bacterial ribosome determined by researchers at the University of Illinois Chicago show that a single water molecule may be the cause - and possible solution - of antibiotic resistance.

20 Jan 2021

Immune systems of COVID-19 patients may rely on antibodies from earlier coronaviruses

The results of a study led by Northern Arizona University and the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, suggest the immune systems of people infected with COVID-19 may rely on antibodies created during infections from earlier coronaviruses to help fight the disease.

20 Jan 2021

Over 100 million in India may have been infected by SARS-CoV-2

A large new study posted on the preprint server medRxiv describes the seropositivity rate to this virus, as well as the persistence of antibodies over time, both neutralizing and others.

19 Jan 2021

Scientists uncover elusive mechanism behind the most severe cases of blood disorder

With a name like glucose-6-phosphate dehydrogenase deficiency, one would think it is a rare and obscure medical condition, but that's far from the truth.

19 Jan 2021

The structure dynamics of the SARS-CoV-2 genome in cells, cell lysates and virions

Now, a new preprint research paper posted to the bioRxiv server describes the structures observed during the lifecycle of the RNA virus in terms of both canonical and alternative structures, RNA-RNA interactions, and replication regulation.

19 Jan 2021

Mapping antibody reactivity in COVID-19 patients by using multi-coronavirus protein microarray

In an exciting, state-of-the-art study currently available on the medRxiv* preprint server, US researchers created a multi-coronavirus protein microarray containing full-length proteins, peptide libraries, and overlapping protein fragments from the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), as well as four other human coronaviruses.

19 Jan 2021

New method reveals how pharmaceuticals induce cancer cell death

Cancer cells are smart when it comes to anti-cancer drugs, evolving and becoming resistant to even the strongest chemotherapies over time.

19 Jan 2021

Effects of low-fat, plant-based diet compared to low-carb, animal-based diet

People on a low-fat, plant-based diet ate fewer daily calories but had higher insulin and blood glucose levels, compared to when they ate a low-carbohydrate, animal-based diet, according to a small but highly controlled study at the National Institutes of Health.

19 Jan 2021

Memory B cell response to SARS-CoV-2 evolves up to 6 months after infection, study finds

A new study shows that the memory B cell response to SARS-Cov-2 evolves between 1.3 and 6.2 months after infection in a manner that is consistent with antigen persistence.

19 Jan 2021

Which SARS-CoV-2 mutations can potentially evade antibody recognition?

A team of US-based researchers has systematically identified SARS-CoV-2 mutations that could potentially evade neutralizing antibodies produced by the current vaccine candidates.

19 Jan 2021

Study predicts good passive immunotherapy donors to combat COVID-19

A US-based research team determine good candidates for convalescent plasma donations in promoting passive immunity among severely-ill COVID-19 patients.

19 Jan 2021

Researchers receive $460,000 NIH grant for brain imaging study

Michael Alosco, PhD, associate professor of neurology at Boston University School of Medicine, and Gil Rabinovici, MD, professor of neurology and radiology at the University of California San Francisco have been awarded a two-year, $460,000 grant from the National Institute of Neurological Disorders and Stroke, which is part of the National Institutes of Health.

19 Jan 2021

Protein C News and Research

Researchers discover rare genetic disorder that affects the brain, heart and facial features

Automated method tracks cortical origin and initial spread of TAU proteins in Alzheimer’s disease

Eliminating key gene could revive exhausted immune cells to battle solid tumors

COVID-19 has transformed the world of vaccines

South African SARS-CoV-2 variant escapes antibody neutralization

Ethacrynic acid, a diuretic drug with potential anti-SARS-CoV-2 activity

Researchers develop new method for charting SARS-CoV-2 spike protein glycosylation

BMP5/7 protein offers promising therapeutics that could halt the progression of Parkinson's disease

Study shows that single water molecule may cause antibiotic resistance

Immune systems of COVID-19 patients may rely on antibodies from earlier coronaviruses

Over 100 million in India may have been infected by SARS-CoV-2

Scientists uncover elusive mechanism behind the most severe cases of blood disorder

The structure dynamics of the SARS-CoV-2 genome in cells, cell lysates and virions

Mapping antibody reactivity in COVID-19 patients by using multi-coronavirus protein microarray

New method reveals how pharmaceuticals induce cancer cell death

Effects of low-fat, plant-based diet compared to low-carb, animal-based diet

Memory B cell response to SARS-CoV-2 evolves up to 6 months after infection, study finds

Which SARS-CoV-2 mutations can potentially evade antibody recognition?

Study predicts good passive immunotherapy donors to combat COVID-19

Researchers receive $460,000 NIH grant for brain imaging study

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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