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Pig stem cells offer a new way to grow human organs for transplantation

In a new paper published in Stem Cell Reports, Bhanu Telugu and co-inventor Chi-Hun Park of the University of Maryland (UMD) Department of Animal and Avian Sciences show for the first time that newly established stem cells from pigs, when injected into embryos, contributed to the development of only the organ of interest (the embryonic gut and liver), laying the groundwork for stem cell therapeutics and organ transplantation.

18 Dec 2020

Research suggests a novel mechanism for modulating emotional behavior

Research led by Si-Qiong June Liu, MD, PhD, Professor of Cell Biology and Anatomy at LSU Health New Orleans School of Medicine, discovered a surprising reciprocal interaction between chemicals in the brain resulting in accelerated loss of molecules that regulate brain cell communication.

17 Dec 2020

Study shows how melanomas assist T cells from identifying and killing tumor cells

Cancers like melanoma are hard to treat, not least because they have a varied bag of tricks for defeating or evading treatments.

17 Dec 2020

Researchers identify neurons that regulate nausea-like responses in mice

At some point, everyone experiences nausea. Whether it occurs after unwisely eating a week-old slice of pizza or as an accompaniment to a serious infection, that queasy, unsettling sensation centered around the stomach is a signal that something is amiss within the body and typically portends a bout of vomiting.

17 Dec 2020

High expression of VRK1 protein can reduce survival in neuroblastoma patients

Researchers from the Departments of Cell Biology and Medical Physiology at the University of Seville have identified that a high expression of the human protein VRK1 is associated with tumour aggressiveness and low survival among neuroblastoma patients.

11 Dec 2020

Scientists use human stem cells and bioengineered scaffold to build whole functioning thymus

Researchers at the Francis Crick Institute and University College London have rebuilt a human thymus, an essential organ in the immune system, using human stem cells and a bioengineered scaffold.

11 Dec 2020

IGC researchers receive three out of six European Research Council grants

Since the establishment of the European Research Council in 2008, the IGC has secured 17 of their competitive grants (7 Starting, 8 Consolidator and 2 Advanced).

10 Dec 2020

Study provides a detailed understanding of the interplay between obesity and cancer

Obesity has been linked to increased risk for over a dozen different types of cancer, as well as worse prognosis and survival.

9 Dec 2020

Researchers identify new therapeutic target to treat patients with type 1 diabetes

Researchers at the University of Utah School of Medicine have identified a new therapeutic target to treat patients with type 1 diabetes.

9 Dec 2020

RNA mutations within common bacterium linked to invasive meningococcal disease

Researchers at Karolinska Institutet in Sweden have come one step closer toward understanding why some people become seriously ill or die from a common bacterium that leaves most people unharmed.

7 Dec 2020

Researchers identify potential drug combination to treat uveal melanoma

Researchers at Huntsman Cancer Institute (HCI) at the University of Utah (U of U) have identified a potential drug combination to treat uveal melanoma, a type of eye cancer.

7 Dec 2020

Researchers use new imaging technique to produce digital reconstruction of eye tissues

A new study by scientists at the University of Southampton has made a breakthrough that could help the search for treatments against age related sight loss.

2 Dec 2020

Researchers devise new molecular imaging strategy to observe the sperm selection process

A protein called CatSper1 may act as a molecular 'barcode' that helps determine which sperm cells will make it to an egg and which are eliminated along the way.

2 Dec 2020

Pharmacophore model helps find key protease inhibitor responsible for COVID-19

A team of San Diego Supercomputer Center (SDSC) researchers recently created a pharmacophore model and conducted data mining of the database of drugs approved by the U.S. Federal Drug Administration (FDA) to find potential inhibitors of papain-like protease of SARS-CoV2, one of the main viral proteins responsible for COVID-19.

2 Dec 2020

Telomere shortening helps prevent cancer in humans

As time goes by, the tips of your chromosomes--called telomeres--become shorter. This process has long been viewed as an unwanted side-effect of aging, but a recent study shows it is in fact good for you.

1 Dec 2020

MIT study shows how the brain is wired for reactive, reflexive movements

When riding your bike to the store you might have two very different reasons to steer: plain old reflex when you something dart into your path, or executive control when you see street signs that indicate the correct route.

1 Dec 2020

Inflammation produced by bacterial infection 'alerts' the brain stem cells

The study, directed by Isabel Fariñas and published in the November digital edition of the journal Cell Stem Cell, reveals that the inflammation produced by a bacterial infection 'alerts' the brain stem cells and prepares their activation for the production of new neurons.

27 Nov 2020

Specific bacterium in the gut associated with IBS symptoms

Researchers at the University of Gothenburg have detected a connection between Brachyspira, a genus of bacteria in the intestines, and IBS -- especially the form that causes diarrhea.

25 Nov 2020

Researchers describe important cause of fatal influenza

It is largely unknown why influenza infections lead to an increased risk of bacterial pneumonia. Researchers at Karolinska Institutet in Sweden have now described important findings leading to so-called superinfections, which claim many lives around the world every year.

25 Nov 2020