Central Nervous System News and Research

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GlobalData: COVID-19 has pushed infectious disease drugs to top therapy area for CSAs

Infectious disease drugs have overtaken oncology as the year’s top therapy area for contract service agreements as companies are shifting their current focus to developing treatments to battle the COVID-19 pandemic.

25 Jul 2020

Neurotransmitter-derived lipidoids help carry drugs across the blood-brain barrier in mice

Biomedical engineers at the Tufts University School of Engineering have developed tiny lipid-based nanoparticles that incorporate neurotranmitters to help carry drugs, large molecules, and even gene editing proteins across the blood-brain barrier and into the brain in mice.

24 Jul 2020

Researchers assess the damage caused by microbubbles in brain injuries

Say there's a bomb attack on a military base. A few of the soldiers suffer concussions and other brain injuries. Could some of the injuries be caused by tiny bubbles that form and collapse within the skull during head trauma?

23 Jul 2020

Mouse model of fatal COVID-19 developed for vaccine and drug testing

Now, a new study published on the preprint server bioRxiv in July 2020 presents an engineered transgenic mouse that reproduces the functional and clinical characteristics of severe human SARS-CoV-2 infection.

21 Jul 2020

Experimental therapy slows zika replication and prevents microcephaly in mice

An international group of researchers have discovered that inhibiting AHR (aryl hydrocarbon receptor), a protein with roles in regulating immunity, stem cell maintenance and cellular differentiation, enables the immune system to combat replication of zika virus in the organism far more effectively.

20 Jul 2020

Novel blood test for heart failure could lead to new diagnostics for COVID-19 patients

A new blood test that reliably predicts outcomes for heart failure patients could lead to new diagnostics and treatments for COVID-19 patients as well, according to newly published research from cardiologists at the University of Alberta.

20 Jul 2020

Higher doses of omega-3 supplements may be needed for averting cognitive decline

For years, a scientific puzzle has bedeviled researchers aiming to fight Alzheimer's disease, a common and incurable form of dementia.

19 Jul 2020

Disseminated cancer cells hijack crucial iron micronutrients from native macrophages

In order to survive within the remote and harsh anatomical microenvironments of the central nervous system, the disseminated cancer cells that cause rare yet deadly leptomeningeal metastases (LM) hijack crucial iron micronutrients from native macrophages, researchers report.

16 Jul 2020

COVID-19 may have an impact on the central nervous system of patients

Depressed mood or anxiety exhibited in COVID-19 patients may possibly be a sign the virus affects the central nervous system, according to an international study led by a University of Cincinnati College of Medicine researcher.

14 Jul 2020

UCR postdoctoral researcher receives 'Pathway to Independence' grant from NIH

Rebekah Charney, a postdoctoral researcher in the School of Medicine at the University of California, Riverside, has received a five-year "Pathway to Independence" grant from the National Institute of Dental and Craniofacial Research of the National Institutes of Health, or NIH.

12 Jul 2020

Biologists discover extraordinary regeneration of injured neurons in zebrafish

Biologists from the University of Bayreuth have discovered a uniquely rapid form of regeneration in injured neurons and their function in the central nervous system of zebrafish.

12 Jul 2020

Study sheds new light on neurobiological processes that control drug-related adaptations

The lab of Jeremy Day, Ph.D., at the University of Alabama at Birmingham, has used single-nucleus RNA sequencing approaches to compare transcriptional responses to acute cocaine in 16 unique cell populations from a portion of the brain called the nucleus accumbens, or NAc.

10 Jul 2020

Cerebrospinal fluid autoantibodies target the brain in some COVID-19 patients

A study conducted by German researchers has shown that the neurological symptoms observed in some patients with coronavirus disease 2019 (COVID-19) may be caused by autoantibodies targeting the brain.

7 Jul 2020

New nanoparticle-based artificial retina prosthesis restores vision in blind rats

An international team of scientists, of which the University of Granada (UGR) is a member, has developed a new nanoparticle-based artificial retina prosthesis that can be injected into the eye.

7 Jul 2020

New vitamin K-based drug eliminates medication-resistant epileptic seizures in mice

In the cover article of the June 11 issue of the Journal of Medicinal Chemistry, a team of researchers at the Medical University of South Carolina, led by Sherine Chan, Ph.D., and James Chou, Ph.D., reports that a new vitamin K-based drug has proved effective in mouse models of medication-resistant seizures.

6 Jul 2020

Researchers receive innovative grants to understand the biological underpinnings of blood cancers

Seeking to ignite the next major breakthroughs to treat blood cancers, The Leukemia & Lymphoma Society (LLS), The Mark Foundation, and The Paul G. Allen Frontiers Group today announced more than $6.75 million awarded to nine of the most exceptional scientists in the field.

1 Jul 2020

Walking backward could help stroke patients to walk again

Walking backward may seem counterintuitive, but to athletes in training, doing so on a treadmill builds strength and agility.

1 Jul 2020

Study shows how the brain's auditory system is affected by HIV

Even with effective antiretroviral therapy, patients infected with the Human Immunodeficiency Virus (HIV) sustain central nervous system damage.

30 Jun 2020

Irritable bowel disease heightens the risk of dementia

Scientists have long explored the link between the gut and the brain. Now, a new study shows that older adults with chronic inflammation of the digestive tract may develop dementia more than seven years earlier than those who do not have the condition.

26 Jun 2020

Protein profile in serum reflects COVID-19 severity

The wide range of manifestations of COVID-19 has continued to baffle investigators. Now, a new study published on the preprint server medRxiv in June 2020 shows that blood proteins in COVID-19 patients change over time, and these can possibly predict or reflect the severity of disease. More, they may present targets for treatment.

25 Jun 2020