Lipoprotein News and Research

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A lipoprotein is a biochemical assembly that contains both proteins and lipids. The lipids or their derivatives may be covalently or non-covalently bound to the proteins.

Rimonabant shows mixed results for slowing progression of coronary disease

The anti-obesity medication rimonabant showed mixed results in slowing progression of coronary artery disease in patients with abdominal obesity and pre-existing coronary disease, according to a new study in the April 2 issue of JAMA.

2 Apr 2008

Severe psoriasis linked to serious medical conditions including cardiovascular disease, depression and cancer

It has long been known that psoriasis, a chronic skin condition characterized by thick, red, scaly plaques that itch and bleed, can have a significant negative impact on a patient's overall quality of life.

25 Mar 2008

Cholesterol-associated gene variants can predict cardiovascular events

A study appearing in this week's New England Journal of Medicine confirms that a combination of gene variants previously associated with cholesterol levels does reflect patients' cholesterol levels and can signify increased risk of heart attack, stroke or sudden cardiac death.

20 Mar 2008

Vegan diet for rheumatoid arthritis patients protects from heart attacks and strokes

A new study suggests that following a gluten-free, vegan diet may offer rheumatoid arthritis patients some protection from heart attacks and strokes.

19 Mar 2008

HDL-associated protein gene linked to heart disease risk

The gene for the HDL-associated protein paraoxonase 1 (PON1) appears to be associated with coronary artery disease and with the risk of developing adverse cardiac events, and variations in both the PON1 gene and its related enzyme activity may increase the risk for cardiovascular disease events, according to a study in the March 19 issue of JAMA , a theme issue on Genetics and Genomics.

19 Mar 2008

An anti-inflammatory response to the vegan diet

Rheumatoid arthritis (RA) patients who eat a gluten-free vegan diet could be better protected against heart attacks and stroke.

18 Mar 2008

Monthly contact with counselor provides some benefit for maintaining weight loss

Weight-loss program participants who had a brief, monthly personal contact intervention - most often a 10-15 minute phone conversation - regained less weight than participants who were in a Web-based intervention or self-directed program, according to a study in the March 12 issue of JAMA, the Journal of the American Medical Association.

12 Mar 2008

Scientists look at 'syringe' assembly in plague bacteria

Bacteria that cause the bubonic plague avoid death in our bodies by injecting our cells with immune evasion proteins.

28 Feb 2008

Patients who prefer to be highly involved don't always see better health outcomes

Patients who prefer to be highly involved in their treatment don't necessarily have better luck managing chronic health conditions, a new study suggests.

26 Feb 2008

Obesity linked to stroke increase among middle-aged women

Middle-aged women's waists aren't the only thing that increased in the last decade. So did their chance of stroke.

21 Feb 2008

Researchers uncover key interaction in cholesterol regulation

Researchers at UT Southwestern Medical Center have determined the specific way in which a destructive protein binds to and interferes with a molecule that removes low-density lipoproteins (LDL), the so-called "bad" cholesterol, from the blood.

4 Feb 2008

Fast-food consumption increases metabolic syndrome risk

Healthy adults who eat two or more servings of meat a day the equivalent of two burger patties increase their risk of developing metabolic syndrome by 25 percent compared with those who eat meat twice a week, according to research published in Circulation: Journal of the American Heart Association.

23 Jan 2008

Simplified scoring system may predict overall CVD risk

Physicians currently evaluate a patient's risk for heart disease, stroke and other cardiovascular diseases (CVD) individually, but a new assessment tool could gauge risk of overall 'or global' CVD and a range of cardiovascular diseases at one time, according to a study published in Circulation: Journal of the American Heart Association.

23 Jan 2008

Smallest particles from vehicle emissions may promote hardening of the arteries

Patients prone to heart disease may one day be told by physicians to avoid not only fatty foods and smoking but air pollution too.

18 Jan 2008

Supplements of lipoic acid could reduce atherosclerosis, weight gain

A new study done with mice has discovered that supplements of lipoic acid can inhibit formation of arterial lesions, lower triglycerides, and reduce blood vessel inflammation and weight gain - all key issues for addressing cardiovascular disease.

15 Jan 2008

Researchers associate six new genetic variants with heart disease risk factor

Using new techniques for rapidly scanning the human genome, researchers have associated levels of cholesterol and triglycerides, two fats in the blood, to 18 genetic variants, six of which represent new DNA regions never before associated with the traits.

15 Jan 2008

New genetic variations associated with lipid levels, risk for coronary artery disease

Environmental and genetic factors influence a person's blood fat, or lipid levels, important risk factors for coronary artery disease (CAD). While there is some understanding of the environmental contribution, the role of genetics has been less defined.

14 Jan 2008