Malignant News and Research

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Engineered stem cells offer new treatment for metastatic bone cancer

Engineered stem cells could help treat metastatic cancers in bone without killing normal surrounding bone.

9 Jul 2019

Researchers discover novel cancer-promoting molecular mechanism

A novel cancer-promoting molecular mechanism has been discovered by Pierluigi Scalia, M.D., Ph.D., with his co-workers at the Sbarro Institute for Cancer Research and Molecular Medicine, Division of Biology, Temple University, the Department of Medical Biotechnologies at University of Siena, Italy and the Italian non-profit research organization ISOPROG, in collaboration with the Center of Biocomputational Sciences, part of the College of Science and Technology in Philadelphia.

8 Jul 2019

Researchers use artificial intelligence to predict molecular classification of colorectal cancer

Treating physicians need information about the molecular subtype of the tumor if they are to provide targeted therapy for colorectal carcinoma.

4 Jul 2019

New discovery may help predict recurrence of pancreatic neuroendocrine tumors

Researchers have discovered two distinct subtypes of pancreatic neuroendocrine tumors – known as pNETs – that have dramatically different risks of recurrence following surgical treatment [or surgery].

4 Jul 2019

New resistance mechanism that prevent formation of blood vessels

Researchers at IDIBELL-ICO describe a new resistance mechanism to therapies that prevent the formation of blood vessels

3 Jul 2019

Physicians trained in dermatoscopy can improve odds for early detection of melanoma

Primary care physicians trained in dermatoscopy can improve odds for early detection of melanoma while reducing the need for invasive biopsies, according to a study in The Journal of the American Osteopathic Association.

1 Jul 2019

Protein linked to malignant melanoma

Almost 300,000 people worldwide develop malignant melanoma each year. The disease is the most serious form of skin cancer and the number of cases reported annually is increasing, making skin cancer one of Sweden's most common forms of cancer.

28 Jun 2019

Promising new approaches in the fight against brain metastasis

Research is currently pursuing several highly promising approaches in the fight against cancers that give rise to metastases in the brain.

28 Jun 2019

Scientists discover pathway that prevents buildup of Alzheimer's protein

St. Jude Children's Research Hospital scientists have discovered a pathway that functions like a car wash to prevent the buildup of a toxic protein associated with Alzheimer's disease. The report appeared online today in the journal Cell.

28 Jun 2019

A metabolic intermediate in the uronic acid pathway impairs lung cancer metastasis

In a study published online in Nature on June 26, research teams led by Dr. YANG Weiwei at the Institute of Biochemistry and Cell Biology of the Chinese Academy of Sciences and Dr. LI Guohui from the Dalian Institute of Chemical Physics of CAS reported a new function of uridine diphosphate glucose (UDP-glucose), a metabolic intermediate in the uronic acid pathway: It impairs lung cancer metastasis by accelerating SNAI1 mRNA decay.

27 Jun 2019

Wear protective clothing to reduce the risk of skin damage from sun's UV rays

Whenever you're outdoors this summer, be sure to take steps to prevent solar erythema, the acute cutaneous reaction to excessive exposure to ultraviolet (UV) radiation.

25 Jun 2019

Veterans with PTSD twice as likely to die from suicide, accidental injury, and viral hepatitis

According to a new study in the American Journal of Preventive Medicine, published by Elsevier, United States Veterans seeking treatment for posttraumatic stress disorder are at increased risk of death compared with the general population.

24 Jun 2019

Adult survivors of pediatric brain tumors may experience cognitive, socioeconomic burdens

Survivors of childhood brain tumors who received radiotherapy and were very young at the time of diagnosis may experience cognitive and socioeconomic burdens decades after treatment, according to a study published early online in CANCER, a peer-reviewed journal of the American Cancer Society.

24 Jun 2019

Non-classical monocytes directly involved in regulation of immune response

Non-classical monocytes were long thought to play a purely surveillance role in the immune system. With the aid of a novel marker, Ludwig-Maximilians-Universitaet in Munich researchers have now shown that they are directly involved in the regulation of immune response

24 Jun 2019

Study calls for more aggressive treatments to improve 5-year survival in glioblastoma patients

Despite improvements in median and short-term survival rates for patients with glioblastoma, the most common brain tumor in adults, the percentage of patients achieving five-year survival remains low, according to new Mayo Clinic research.

23 Jun 2019

Study emphasizes need for more aggressive treatments for glioblastoma patients

20 Jun 2019

Research findings lead to new clinical trial for people with myelofibrosis

Researchers at Huntsman Cancer Institute at the University of Utah (U of U) discovered in laboratory studies that an experimental drug called selinexor may block a crucial survival pathway exploited by myelofibrosis cells.

20 Jun 2019

Men who eat yogurt twice a week are less likely to develop bowel cancer

Eating two or more servings of yogurt (over 245g) per week can reduce the risk of men developing pre-cancerous growths that can lead to bowel cancer.

19 Jun 2019

Miracle machine makes heroic rescues — and leaves patients in limbo

The latest miracle machine in modern medicine — whose use has skyrocketed in recent years — is saving people from the brink of death: adults whose lungs have been ravaged by the flu; a trucker who was trapped underwater in a crash; a man whose heart had stopped working for an astonishing seven hours.

18 Jun 2019

Three beagles successfully identify lung cancer by scent, shows study

Three beagles successfully showed they are capable of identifying lung cancer by scent, a first step in identifying specific biomarkers for the disease.

18 Jun 2019