Neurodegenerative Diseases News and Research

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Researchers test novel gene regulation approach to treat brain diseases

Researchers at the DZNE (Germany), at Massachusetts General Hospital (USA) and at the genomic medicine company Sangamo Therapeutics, Inc. tested a novel gene regulation approach to treat brain diseases such as Alzheimer's in laboratory studies.

22 Mar 2021

Novel technology may reveal the brain's mysteries

A team of scientists, led by researchers at Northwestern University, Shirley Ryan AbilityLab and the University of Illinois at Chicago (UIC), has developed novel technology promising to increase understanding of how brains develop, and offer answers on repairing brains in the wake of neurotrauma and neurodegenerative diseases.

22 Mar 2021

Genetic engineering strategy dramatically reduces tau levels in Alzheimer's animal model

Researchers have used a genetic engineering strategy to dramatically reduce levels of tau--a key protein that accumulates and becomes tangled in the brain during the development of Alzheimer's disease--in an animal model of the condition.

21 Mar 2021

Researchers unveil a neuroprotective pathway that suppresses ALS

In general, the RAN proteins are more abundant in the cell nucleus, but in patients with Lou Gehrig's disease, they begin to leak out into the cytoplasm, thereby resulting in abnormal concentration differences.

19 Mar 2021

New high-throughput system for testing drug candidates to treat brain diseases

On the basis of a license agreement with the German Center for Neurodegenerative Diseases (DZNE) and the Leibniz Institute of Polymer Research Dresden (IPF), the Dresden-based start-up "Neuron-D GmbH" is developing a high-throughput system for testing drug candidates to treat neurodegenerative diseases.

18 Mar 2021

UTSW researchers identify the structure of a key cell-surface protein

UT Southwestern researchers have identified the structure of a key member of a family of proteins called nicotinic acetylcholine receptors in three different shapes.

17 Mar 2021

Modern facial detection and analysis algorithms could help track changes due to Parkinson's disease

Parkinson's disease (PD) is a well-studied neurodegenerative disorder that affects between 7 and 10 million people worldwide.

16 Mar 2021

Sex differences play roles in how patients respond to brain diseases

Men and women are impacted differently by brain diseases, like Alzheimer's disease and Parkinson's disease. Researchers are urging their colleagues to remember those differences when researching treatments and cures.

16 Mar 2021

48Hour Discovery and Merck join hands to accelerate drug development

48Hour Discovery and CQDM are proud to announced that the company has been awarded $800,000 for peptide drug discovery using its patented drug discovery platform.

15 Mar 2021

Novel tool can add or remove sugar from proteins

Sugar has been called "evil," "toxic," and "poison." But the body needs sugars, too. Sugar molecules help cells recognize and fight viruses and bacteria, shuttle proteins from cell to cell, and make sure those proteins function.

12 Mar 2021

Newly discovered cellular stress enzyme may be a target for neurodegenerative disease treatments

An enzyme called MARK2 has been identified as a key stress-response switch in cells in a study by researchers at Johns Hopkins Bloomberg School of Public Health.

11 Mar 2021

Maternal pomegranate juice intake may reduce risk of brain injury in IUGR infants

Intrauterine growth restriction (IUGR) is common and concerning, but few therapeutic options exist for pregnant mothers who receive this diagnosis.

11 Mar 2021

Study identifies key gene associated with age-related brain deterioration

A new study led by the University of Portsmouth has identified that one of the major factors of age-related brain deterioration is the loss of a substance called myelin.

10 Mar 2021

Injectable scaffolding materials facilitate rapid healing after spinal cord injuries

Spinal cord injuries can be life-changing and alter many important neurological functions. Unfortunately, clinicians have relatively few tools to help patients regain lost functions.

9 Mar 2021

First complete atlas of how mutations affect the formation of amyloid plaques in Alzheimer’s disease

A study published in the journal eLife made all the possible mutations in the amyloid beta peptide and tested how they influence its aggregation into plaques, a pathological hallmark of Alzheimer's disease.

9 Mar 2021

New tool helps choose the best intervention for each dementia patient

Every three seconds, a new case of dementia is diagnosed somewhere in the world. The term encompasses a group of neurodegenerative diseases that have no cure and which affect memory, cognitive abilities and behavior, and includes Alzheimer's disease.

9 Mar 2021

Study shows how mutant huntingtin protein triggers brain cell death

In 1993, scientists discovered that a single mutated gene, HTT, caused Huntington's disease, raising high hopes for a quick cure. Yet today, there's still no approved treatment.

7 Mar 2021

Researchers identify human BCAS3 and C16orf70 as novel autophagic proteins

Autophagy is an intracellular degradation process of cytosolic materials and damaged organelles. Researchers at Ubiquitin Project of TMIMS have been studying the molecular mechanism of mitophagy, the selective autophagy process to eliminate damaged mitochondria.

5 Mar 2021

New evidence supports the use of antisense oligonucleotides as feasible therapeutic strategy for MDS

Many cognitive neurodevelopmental disorders are a result of too many or too few copies of certain genes or chromosomes.

5 Mar 2021

AI-based method for repurposing existing drugs into potential treatments for Alzheimer's

New treatments for Alzheimer's disease are desperately needed, but numerous clinical trials of investigational drugs have failed to generate promising options.

4 Mar 2021

Neurodegenerative Diseases News and Research

Researchers test novel gene regulation approach to treat brain diseases

Novel technology may reveal the brain's mysteries

Genetic engineering strategy dramatically reduces tau levels in Alzheimer's animal model

Researchers unveil a neuroprotective pathway that suppresses ALS

New high-throughput system for testing drug candidates to treat brain diseases

UTSW researchers identify the structure of a key cell-surface protein

Modern facial detection and analysis algorithms could help track changes due to Parkinson's disease

Sex differences play roles in how patients respond to brain diseases

48Hour Discovery and Merck join hands to accelerate drug development

Novel tool can add or remove sugar from proteins

Newly discovered cellular stress enzyme may be a target for neurodegenerative disease treatments

Maternal pomegranate juice intake may reduce risk of brain injury in IUGR infants

Study identifies key gene associated with age-related brain deterioration

Injectable scaffolding materials facilitate rapid healing after spinal cord injuries

First complete atlas of how mutations affect the formation of amyloid plaques in Alzheimer’s disease

New tool helps choose the best intervention for each dementia patient

Study shows how mutant huntingtin protein triggers brain cell death

Researchers identify human BCAS3 and C16orf70 as novel autophagic proteins

New evidence supports the use of antisense oligonucleotides as feasible therapeutic strategy for MDS

AI-based method for repurposing existing drugs into potential treatments for Alzheimer's

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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