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Researchers create 3D in vitro model that reveals the origins of human spine

The spinal column is the central supporting structure of the skeleton in all vertebrates. Not only does it provide a place for muscles to attach, it also protects the spinal cord and nerve roots. Defects in its development are known to cause rare hereditary diseases.

28 Apr 2022

How do mosquito bites affect immunity?

A new study looks at the immunomodulatory effects of mosquito bites, using Aedes aegypti as the model species and humans as the host.

28 Apr 2022

Exploring oncolytic viral therapeutics and immunotherapies derived from DNA and RNA

A new review initially described the developments in cancer-based medicines that included vaccinations, vector-based techniques, and genome injection using DNA and RNA-based nucleic acid therapeutics.

28 Apr 2022

“Keto” molecule could someday become a part of colorectal cancer care and prevention

A molecule produced in the liver in response to low-carb "ketogenic" diets has a powerful effect in suppressing colorectal tumor growth and may be useful as a preventive and treatment of such cancers, according to a new study from researchers at the Perelman School of Medicine at the University of Pennsylvania.

27 Apr 2022

The potency of halicin against the main protease of SARS-CoV-2

A new paper published in Current Research in Chemical Biology discusses the potential of a molecule called halicin against SARS-CoV-2.

26 Apr 2022

ST6Gal-I–mediated sialylation of the EGFR modulates cell mechanics and enhances cancer invasion

For more than two decades, University of Alabama at Birmingham researcher Susan Bellis, Ph.D., has studied how the addition of sialic acid to various proteins increases cancer resistance and oncogenicity.

22 Apr 2022

Single-cell atlas of non-hematopoietic cells provides insights into lymphoma stromal biology

Researchers from the University of Tsukuba identify gene expression signatures in different types of lymph nodes cells that play an active role in the development of lymphomas.

21 Apr 2022

Dual release microparticle system promotes cranial bone defect healing

A new dual delivery system designed to sequentially release BMP2 and IGF1 in microparticles in an injectable hydrogel successfully healed an 8-mm cranial defect in rats.

21 Apr 2022

Study explores microbial genetic engineering approach as a replacement for shark livering for squalene

A new study examined possible genetic engineering approaches that could be utilized to tailor the metabolic processes of yeasts, bacteria, and thraustochytrids to optimize the synthesis of squalene.

21 Apr 2022

RNA splicing abnormalities in COVID-19 patients

This study entailed the integration of multiple-omics datasets to examine the dysregulation in the host splicing mechanism and alteration in protein isoforms among COVID-19 patients.

20 Apr 2022

CAR T-Cell Therapy: The Future of Cancer and HIV Treatment?

In this interview, News-Medical speaks to Professor Jun Huang about CAR T-cell therapy and its future as a potential treatment for cancer or HIV.

20 Apr 2022

High performance microplates for enhanced cell growth and survival

The Sero Krystal™ PDL range of coated microplates from Porvair Sciences set a new benchmark for reproducible cell culture even with challenging cell types.

From Porvair Sciences Limited 20 Apr 2022

Discovery can lead to new antiviral treatments against Crimean-Congo hemorrhagic fever

Researchers at Karolinska Institutet in Sweden have identified key signaling pathways that when blocked by existing drug candidates limit reproduction of the Crimean-Congo hemorrhagic fever (CCHF) virus.

19 Apr 2022

SARS-CoV-2 RBD is a selective integrin agonist

Researchers assess the Arg-Gly-Asp (RGD) motif-mediated binding of the SARS-CoV-2 RBD and integrin receptors.

18 Apr 2022

Avasimibe inhibits SARS-CoV-2 and boosts T-cell responses

Researchers demonstrate that avasimibe-mediated inhibition of ACAT blocks the entry and fusion of SARS-CoV-2 in different cell types.

18 Apr 2022

Scientists investigate how gut bacteria directly control the activity of specific neurons

Gut microbiota by-products circulate in the bloodstream, regulating host physiological processes including immunity, metabolism and brain functions.

15 Apr 2022

Researchers identify certain gene regulation signatures in CAR T-resistant leukemia patients

Acute lymphoblastic leukemia (ALL) cells from patients whose cancers did not respond to CD19-targeted CAR T therapy had gene regulation signatures that could potentially facilitate treatment resistance, according to results presented at the AACR Annual Meeting 2022, held April 8-13.

13 Apr 2022

Proliferation News and Research

Researchers create 3D in vitro model that reveals the origins of human spine

How do mosquito bites affect immunity?

Exploring oncolytic viral therapeutics and immunotherapies derived from DNA and RNA

“Keto” molecule could someday become a part of colorectal cancer care and prevention

The potency of halicin against the main protease of SARS-CoV-2

ST6Gal-I–mediated sialylation of the EGFR modulates cell mechanics and enhances cancer invasion

Single-cell atlas of non-hematopoietic cells provides insights into lymphoma stromal biology

Dual release microparticle system promotes cranial bone defect healing

Study explores microbial genetic engineering approach as a replacement for shark livering for squalene

RNA splicing abnormalities in COVID-19 patients

CAR T-Cell Therapy: The Future of Cancer and HIV Treatment?

High performance microplates for enhanced cell growth and survival

Discovery can lead to new antiviral treatments against Crimean-Congo hemorrhagic fever

SARS-CoV-2 RBD is a selective integrin agonist

Avasimibe inhibits SARS-CoV-2 and boosts T-cell responses

Scientists investigate how gut bacteria directly control the activity of specific neurons

Researchers identify certain gene regulation signatures in CAR T-resistant leukemia patients

Nanocell COVID-19 vaccine elicits potent neutralizing response

Brain charts show changing morphology by age

Shared gene expression signatures in type 1 diabetics treated with IL-2 and COVID-19 patients

Industry Focus eBook - Cell biology (5th edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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