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Modified natural killer cells show neutralizing and multivalent potential against SARS-CoV-2 in vitro

A new study suggests that modified natural killer cells, which express a chimeric antigen receptor using S309 antibody, can bind to and inactivate SARS-CoV-2 spike protein in vitro.

18 Jan 2021

Angiopoietin-2 is a crucial determinant of COVID-19 prognosis, study finds

A team of scientists from the United States and Sweden has recently demonstrated that increased levels of a proinflammatory cytokine, angiopoietin-2, is responsible for hypercoagulation observed in severe COVID-19 patients.

18 Jan 2021

Could procalcitonin indicate bacterial co-infections in COVID-19 patients?

A recent study conducted by Austin Health, Australia, has revealed that the serum level of procalcitonin can be a strong indicator of bacterial co-infection with COVID-19.

18 Jan 2021

New SARS-CoV-2 variant emerges in the U.S.

Even as the rollout of vaccines all over the world brings a glimmer of hope that the current coronavirus disease 2019 (COVID-19) pandemic may end in the near future, new variants continue to emerge, some with the potential to escape vaccine-induced or therapeutic antibodies. Now, a new preprint research paper published on the bioRxiv server describes a new American variant that may have become the dominant strain in the USA.

18 Jan 2021

SARS-CoV-2 anti-N rigid monoclonal antibodies provide accurate early diagnosis

An interesting new preprint research paper that was posted on the bioRxiv* server recently describes the use of rigid monoclonal antibodies (mAbs) in contrast to flexible mAbs, and how this affects the binding of multiple mAbs to the same antigen.

17 Jan 2021

Study sheds light on the causes of debilitating gut pain

A new study, published in the journal Nature, reports evidence from mice and humans that a novel mechanism contributes to chronic gut pain.

17 Jan 2021

A high-temperature tolerant SARS-CoV-2 derived immunogen as a potential vaccine candidate

There have been significant efforts worldwide to combat COVID-19, the disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). One prominent strategy has been to develop vaccines against the virus. Numerous vaccine candidates are under development, and a handful have now been approved for use by several countries.

17 Jan 2021

Analysis supports phase 3 trials of Johnson & Johnson's COVID-19 vaccine

Researchers in the Netherlands, the United States, and Belgium have presented early-stage clinical trial results demonstrating the safety and efficacy of Johnson & Johnson's vaccine candidate for coronavirus disease 2019 (COVID-19).

17 Jan 2021

Study reveals possible SARS-CoV-2 escape mutant that may re-infect immune individuals

A recent study by US researchers shows how the 501Y.V2 variant of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), characterized by several mutations, is able to escape neutralization by present first-wave anti-SARS-CoV-2 antibodies and potentially re-infect COVID-19 convalescent individuals.

17 Jan 2021

Scientists discover new treatment target for osteoarthritis-like knee cartilage degeneration

There is currently no cure for osteoarthritis, but a group of scientists believe they've discovered a method through which a simple knee injection could potentially stop the disease's effects.

16 Jan 2021

New therapeutic approach enables functional recovery after spinal cord injury in mice

Using gene therapy, a research team has succeeded for the first time in getting mice to walk again after a complete cross-sectional injury. The nerve cells produced the curative protein themselves.

16 Jan 2021

Researchers solve the structure, function of mitochondrial sorting and assembly machinery

Mitochondria are vital for the human body as cellular powerhouses: They possess more than 1,000 different proteins, required for many central metabolic pathways.

16 Jan 2021

National consortium to study the effects of emerging SARS-CoV-2 mutations

A new national research project to study the effects of emerging mutations in SARS-CoV-2 will be launched with £2.5 million of funding from UK Research and Innovation.

15 Jan 2021

Study reveals significant role of ADAMTS1 protein in uveal melanoma

Scientists from the University of Granada and GENYO (Pfizer-University of Granada-Andalusian Government Centre for Genomics and Oncological Research), in a study led by Juan Carlos Rodríguez-Manzaneque, have demonstrated the significant role of a protein called ADAMTS1 in uveal melanoma, one of the rarest and most aggressive cancers that exist, which develops in the eye.

15 Jan 2021

Religious beliefs modulate protein expression linked to cardiovascular disease in US South Asians

The Study on Stress, Spirituality and Health (SSSH), a cutting-edge proteomics analysis, suggests that religious beliefs modulate protein expression associated with cardiovascular disease in South Asians in the United States.

15 Jan 2021

Survey: Households with children purchase higher-fat and larger quantities of dairy products

American dairy consumers are often influenced by a variety of factors that can affect their buying habits. These factors include taste, preference, government information, cultural background, social media, and the news.

15 Jan 2021

Severe COVID-19 linked to genetic make-up of both host and virus, say researchers

A recent study conducted by a team of international scientists has revealed that the infectivity and pathogenicity of SARS-CoV-2 strongly depend on the genetic background of both the virus and the host.

15 Jan 2021

Image-based deep learning haplotype-guided study maps the global adaptation of SARS-CoV-2

A new study used deep learning with image recognition technology to trace the emergence of variants with increased viral fitness. Higher fitness leads to rapid expansion of these lineages in the areas where they are introduced. This type of study could facilitate the development of more effective antibodies and vaccines to help contain the pandemic.

15 Jan 2021

Concern develops over Brazilian SARS-CoV-2 variant

Concern is being expressed over a variant of SARS-CoV-2 that shows similar mutations to the South African and UK variants of the disease.

15 Jan 2021

New antiviral repurposing study finds peptides that could prevent SARS-CoV-2-ACE2 binding

A new study reports the antiviral potential of peptides against SARS-CoV-2's spike protein.

15 Jan 2021

Protein C News and Research

Modified natural killer cells show neutralizing and multivalent potential against SARS-CoV-2 in vitro

Angiopoietin-2 is a crucial determinant of COVID-19 prognosis, study finds

Could procalcitonin indicate bacterial co-infections in COVID-19 patients?

New SARS-CoV-2 variant emerges in the U.S.

SARS-CoV-2 anti-N rigid monoclonal antibodies provide accurate early diagnosis

Study sheds light on the causes of debilitating gut pain

A high-temperature tolerant SARS-CoV-2 derived immunogen as a potential vaccine candidate

Analysis supports phase 3 trials of Johnson & Johnson's COVID-19 vaccine

Study reveals possible SARS-CoV-2 escape mutant that may re-infect immune individuals

Scientists discover new treatment target for osteoarthritis-like knee cartilage degeneration

New therapeutic approach enables functional recovery after spinal cord injury in mice

Researchers solve the structure, function of mitochondrial sorting and assembly machinery

National consortium to study the effects of emerging SARS-CoV-2 mutations

Study reveals significant role of ADAMTS1 protein in uveal melanoma

Religious beliefs modulate protein expression linked to cardiovascular disease in US South Asians

Survey: Households with children purchase higher-fat and larger quantities of dairy products

Severe COVID-19 linked to genetic make-up of both host and virus, say researchers

Image-based deep learning haplotype-guided study maps the global adaptation of SARS-CoV-2

Concern develops over Brazilian SARS-CoV-2 variant

New antiviral repurposing study finds peptides that could prevent SARS-CoV-2-ACE2 binding

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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