Bone News and Research

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Common garden plant may hold cure for leukemia

Scientists in the U.S. believe they have identified a new pathway in the progression of chronic myelogenous leukemia (CML).

12 Dec 2005

Cancer road map shows how cancer spreads

Scientists at Cornell University in New York have discovered how cancer spreads from a primary site to other places in the body.

11 Dec 2005

Dog gene map may help explain human diseases

U.S. scientists say a detailed analysis of the dog genome answers such questions as how dogs of a different breed still belong to the same species, and may also explain some aspects of human health and biology.

11 Dec 2005

Risedronate prevents bone loss and periodontal disease

Drugs that reverse and prevent bone loss due to osteoporosis also significantly ward off periodontal disease, according to a graduate of the Case Western Reserve University School of Dental Medicine who reports in the current Menopause journal article, "Periodontal Assessments of Postmenopausal Women Receiving Risedronate."

7 Dec 2005

Stem cells may cause some forms of bone cancer

The researchers are the first to identify a population of cells with characteristics of adult and embryonic stem cells in cultures derived from biopsies of patients' bone tumors. They describe their findings in the medical journal Neoplasia.

7 Dec 2005

Generation of neoantigenic epitopes after posttranslational modification of Type II collagen by factors present within the inflamed joint

Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation of the joints, which gradually erodes the cartilage and bone.

7 Dec 2005

Mesoblast recruits first patients for pilot clinical trials

Australia's adult stem cell company, Mesoblast Limited, today announced that several patients have now been formally recruited for its Pilot Clinical Trials.

6 Dec 2005

New study sheds light on role of type II collagen in rheumatoid arthritis

Rheumatoid arthritis (RA) is an autoimmune disease which gradually erodes cartilage and bone and is characterised by chronic inflammation of the joints.

6 Dec 2005

Heart pump technology - comparative study

Chicago's first participant in the RELIANT (Randomized Evaluation of the Novacor(r) LVAS In A Non-Transplant Population) research study recently went home from Northwestern Memorial Hospital.

5 Dec 2005

Dialysis patients may be overmedicated

Changes in a widely used assay (blood test) for parathyroid hormone (PTH) have made its use with the established guidelines for end stage renal disease clinical management both inappropriate and potentially harmful to patients. This research is published in the journal Seminars in Dialysis.

5 Dec 2005

Master switch for blood cell development detected

Blood cells develop from blood stem cells in the bone marrow. Their development is regulated by roughly 20 gene regulators or transcription factors.

28 Nov 2005

GRK5's role in restenosis

Researchers at Jefferson Medical College have begun to clarify the role of a protein - and potential drug target - in the process by which arteries re-clog after treatment.

28 Nov 2005

$Radiotherapy for certain cancers increases the risk of pelvic fractures$

Radiotherapy for certain cancers increases the risk of pelvic fractures

A new study suggests that older women who receive pelvic radiation treatment for cervical, anal or rectal cancer may have an increased risk of pelvic fracture.

24 Nov 2005

Compound from Salinispora (marine bacteria) kills blood cancer cells

An anti-cancer compound derived from bacteria dwelling in ocean-bottom sediments appears in laboratory tests to be a potent killer of drug-resistant multiple myeloma cells, and potentially with less toxicity than current treatments, report Dana-Farber Cancer Institute researchers in the November issue of Cancer Cell.

21 Nov 2005

Carbonic anhydrase and CO2 sensing during Cryptococcus neoformans growth, differentiation, and virulence

By using pathogenic fungi as model systems for understanding fungal diseases, two groups of researchers are reporting new work that offers insight into how carbon dioxide (CO2) governs the morphogenic changes that allow pathogenic fungi to survive in different environments and invade the human body

21 Nov 2005

Drug pravastatin may provide a previously unknown cardiovascular benefit

The drug pravastatin, which is used widely to decrease high cholesterol, may provide a previously unknown cardiovascular benefit in addition to lowering lipids.

20 Nov 2005

Plant extract forskolin may lead to leukemia treatment

Scientists here have identified a new pathway in the progression of chronic myelogenous leukemia (CML). They also discovered that an extract from the root of a common ornamental plant can suppress the process.

20 Nov 2005

FLT-1 blockers, cutting the legs of leukaemia

Leukaemia is characterised by an uncontrolled growth of abnormal blood cells in the bone marrow (BM).

14 Nov 2005

Biomedical device allows stem cells derived from adult bone marrow to be grown in sufficient quantities to permit far more research

Human stem cells offer tremendous hope for the development of revolutionary medical treatments for these and a variety of other human health problems.

14 Nov 2005

New understanding of the disease process involved in atherosclerosis

The progression of the artery-clogging disease atherosclerosis is linked to the inability of specialized bone marrow cells to continuously repair damage to the arterial lining, Duke University Medical Center researchers have demonstrated.

13 Nov 2005