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Kaposi’s sarcoma risk factors revealed

Scientists have uncovered an intriguing relationship between the risk for Kaposi’s sarcoma, smoking, and the use of highly active antiretroviral therapy.

25 Feb 2013

Harmful effects of stress may be key to managing chronic pain

For chronic pain sufferers, such as people who develop back pain after a car accident, avoiding the harmful effects of stress may be key to managing their condition.

25 Feb 2013

Circassia announces results from ToleroMune cat allergy phase II clinical study

Circassia Ltd, a specialty biopharmaceutical company focused on allergy, today announced the results of a phase II clinical study showing that a short course of just four doses of its ToleroMune cat allergy therapy maintained improvements in patients' symptoms two years after the start of treatment.

25 Feb 2013

Omalizumab fast, safe and well-tolerated in teens and adults with chronic spontaneous urticaria

An international team of researchers has found that a once-a-month, high-dose injection of a commonly used asthma drug is highly effective in treating teens and adults chronically afflicted with hives and severe, itchy rash. The drug, omalizumab, was tested on 323 people at 55 medical centers for whom standard antihistamine therapy failed to quell their underlying, allergy-like reaction, known as chronic idiopathic urticaria or chronic spontaneous urticaria.

25 Feb 2013

Two USC scientists develop new algorithm to help predict value of DNA sequencing

Two USC scientists have developed an algorithm that could help make DNA sequencing affordable enough for clinics - and could be useful to researchers of all stripes.

25 Feb 2013

Novel anti-cancer drug conjugates to be evaluated by Ablynx and Spirogen

Ablynx [Euronext Brussels: ABLX] and Spirogen Ltd. announce a research collaboration to evaluate the potential of a novel anti-cancer drug conjugate combining Spirogen's proprietary cytotoxic drugs, pyrrolobenzodiazepines (PBD), and associated linker technology, with Nanobodies® generated using Ablynx’s proprietary technology platform.

25 Feb 2013

Ampio to initiate dose escalation run-in study for treatment of knee osteoarthritis

Ampio Pharmaceuticals, Inc. announced today that it's Phase III clinical study of Ampion™ for the treatment for osteoarthritis of the knee will include a dose-escalation run-in study as recommended by the FDA.

25 Feb 2013

Individuals with psychogenic disease do have brains that function differently

Psychogenic diseases, formerly known as 'hysterical' illnesses, can have many severe symptoms such as painful cramps or paralysis but without any physical explanation. However, new research from the University of Cambridge and UCL (University College London) suggests that individuals with psychogenic disease, that is to say physical illness that stems from emotional or mental stresses, do have brains that function differently.

25 Feb 2013

Researchers map complex interactions of proteins that control inflammation

Inflammatory response plays a major role in both health protection and disease generation. While the symptoms of disease-related inflammatory response have been know, scientists have not understood the mechanisms that underlie it.

25 Feb 2013

FDA alerts patients and health care providers of voluntary recall of Omontys by Affymax

The U.S. Food and Drug Administration is alerting health care providers and patients of a voluntary nationwide recall of all lots of Omontys Injection by Affymax, Inc., of Palo Alto, Calif., and Takeda Pharmaceuticals Company Limited, of Deerfield, Ill.

25 Feb 2013

Study shows how pseudogenes can regulate activity of PTEN cancer-related gene

Small stretches of DNA in the human genome are known as "pseudogenes" because, while their sequences are nearly identical to those of various genes, they have long been thought to be non-coding "junk" DNA.

25 Feb 2013

Researchers identify new pseudogene that regulates tumour-suppressing PTEN

Researchers at Karolinska Institutet in Sweden have identified a new so-called pseudogene that regulates the tumour-suppressing PTEN gene. They hope that this pseudogene will be able to control PTEN to reverse the tumour process, make the cancer tumour more sensitive to chemotherapy and to prevent the development of resistance.

25 Feb 2013

HIV epidemics and extra-couple relationships: an interview with Steve Bellan, University of Texas

The epicentre of the HIV pandemic is in sub-Saharan Africa, though prevalence of infection varies dramatically between countries for reasons not completely understood.

25 Feb 2013

WUSTL to develop 3-D computer models of brain biomechanics to better understand TBI

Washington University in St. Louis engineering researchers have received a five-year, $2.25 million grant to better understand traumatic brain injuries in efforts to improve methods for prevention and treatment.

25 Feb 2013

Evidence could prove that humans have unique cortical brain networks

Our ancestors evolutionarily split from those of rhesus monkeys about 25 million years ago. Since then, brain areas have been added, have disappeared or have changed in function. This raises the question, 'Has evolution given humans unique brain structures?'. Scientists have entertained the idea before but conclusive evidence was lacking. By combining different research methods, we now have a first piece of evidence that could prove that humans have unique cortical brain networks.

25 Feb 2013

NAS to establish National Academy of Sciences Prize in Psychological and Cognitive Sciences

Richard C. Atkinson has made a gift of $3.5 million to the National Academy of Sciences to establish the National Academy of Sciences Prize in Psychological and Cognitive Sciences.

25 Feb 2013

Orphan, CU to develop enzyme replacement therapy for CBS-deficient homocystinuria

The University of Colorado (CU) has signed exclusive, worldwide licensing and collaboration agreements with rare-disease research-and-development firm Orphan Technologies Ltd to develop an enzyme replacement therapy for Cystathionine Beta-Synthase (CBS) -deficient homocystinuria, a rare, inherited metabolic disease that is often fatal at a young age.

25 Feb 2013

Researchers discover new way to accelerate mass spectrometer that identifies proteins

Researchers at the University of Wisconsin-Madison have found a new way to accelerate a workhorse instrument that identifies proteins. The high-speed technique could help diagnose cancer sooner and point to new drugs for treating a wide range of conditions.

25 Feb 2013

Va. lawmakers establish panel to work on Medicaid expansion

Concerns from Attorney General Ken Cuccinelli almost derailed the fragile compromise but revisions secured bipartisan support to pass the bill. Democrats hope it will lead to 400,000 uninsured Virginians moving to Medicaid under the federal health law.

25 Feb 2013

Study identifies changes that could explain stability of malaria elimination

Many nations battling malaria face an economic dilemma: spend money indefinitely to control malaria transmission or commit additional resources to eliminate transmission completely. A review of malaria elimination conducted by researchers at the Johns Hopkins Malaria Research Institute and other institutions suggests stopping malaria transmission completely has longlasting benefits for many countries and that once eliminated, the disease is unlikely to reemerge over time.

24 Feb 2013

Research News and Research

Kaposi’s sarcoma risk factors revealed

Harmful effects of stress may be key to managing chronic pain

Circassia announces results from ToleroMune cat allergy phase II clinical study

Omalizumab fast, safe and well-tolerated in teens and adults with chronic spontaneous urticaria

Two USC scientists develop new algorithm to help predict value of DNA sequencing

Novel anti-cancer drug conjugates to be evaluated by Ablynx and Spirogen

Ampio to initiate dose escalation run-in study for treatment of knee osteoarthritis

Individuals with psychogenic disease do have brains that function differently

Researchers map complex interactions of proteins that control inflammation

FDA alerts patients and health care providers of voluntary recall of Omontys by Affymax

Study shows how pseudogenes can regulate activity of PTEN cancer-related gene

Researchers identify new pseudogene that regulates tumour-suppressing PTEN

HIV epidemics and extra-couple relationships: an interview with Steve Bellan, University of Texas

WUSTL to develop 3-D computer models of brain biomechanics to better understand TBI

Evidence could prove that humans have unique cortical brain networks

NAS to establish National Academy of Sciences Prize in Psychological and Cognitive Sciences

Orphan, CU to develop enzyme replacement therapy for CBS-deficient homocystinuria

Researchers discover new way to accelerate mass spectrometer that identifies proteins

Va. lawmakers establish panel to work on Medicaid expansion

Study identifies changes that could explain stability of malaria elimination

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