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NIH and EPA announce new chemical toxicity testing agreement

Testing the safety of chemicals ranging from pesticides to household cleaners will benefit from new technologies and a plan for collaboration, according to federal scientists from the National Institutes of Health (NIH) and the U.S. Environmental Protection Agency (EPA), who today announced a new toxicity testing agreement.

17 Feb 2008

Identical twins are not genetically identical

This surprising finding is presented by American, Swedish, and Dutch scientists in a study being published today in the prestigious journal American Journal of Human Genetics.

17 Feb 2008

Major milestone in the culturing of human blood stem cells

Patients with leukemia, certain autoimmune diseases and genetic defects such as sickle-cell anemia can be treated with blood stem cells either from a donor's bone marrow or from cord blood - but the supply of effective stem cells often runs short.

17 Feb 2008

Search for genes tied to social behavior

The first genome-wide search for genes governing social behavior has found that even the simplest social creatures - the amoebae Dictyostelium discoideum - have more than 100 genes that help regulate their cooperative behavior.

14 Feb 2008

Location location location, even for genes

Moving an active gene from the interior of the nucleus to its periphery can inactivate that gene report scientists from the University of Chicago Medical Center in an article to be published early online Feb.13, 2008, in the journal Nature.

14 Feb 2008

Discovery of 'overdrive' protein could broaden drug design options

New research by scientists at the University of North Carolina at Chapel Hill shows for the first time that an important family of proteins known to function at the cell surface also functions at a site within the cell.

13 Feb 2008

Evolving complexity out of junk DNA

The study, published in Proceedings of the National Academy of Sciences, USA, claims to have solved this scientific riddle by analysing the genomics of primitive living fishes such as sharks and lampreys and their spineless relatives, such as the sea squirts.

12 Feb 2008

Beginnings of complex life traced to microRNA

Dartmouth College researchers and colleagues from the University of Bristol in the U.K. have traced the beginnings of complex life, i.e. vertebrates, to microRNA.

12 Feb 2008

Moss protein plays role in Alzheimer's disease

Preventing Alzheimer's from developing is a goal of Raphael Kopan, Ph.D., professor of molecular biology and pharmacology at the Washington University School of Medicine.

11 Feb 2008

Seven new prostate cancer genetic risk factors identified

Cancer Research UK funded scientists have found seven new sites in the human genome that are linked to men's risk of developing prostate cancer. Their findings are published in Nature Genetics today.

11 Feb 2008

Revelation of new genes linked to prostate cancer could single out high risk men

The discovery by researchers of at least ten new genes associated with prostate cancer could in future be used to accurately identify high-risk men.

11 Feb 2008

Scientists reveal a new target to fight bad cholesterol

Scientists have uncovered a new region in the genome that is responsible for the body's ability to regulate bad cholesterol which is linked to heart attack and stroke.

8 Feb 2008

Researchers decode genetics of chlorophyll d

A bacterium that harvests far-red light by making a rare form of chlorophyll (chlorophyll d) has revealed its genetic secrets, according to a team of researchers who recently sequenced the bacteria's genome.

8 Feb 2008

Scientists find how PARP-1 protein binds to genes and regulates human genome

Out of chaos, control: Cornell University molecular biologists have discovered how a protein called PARP-1 binds to genes and regulates their expression across the human genome.

8 Feb 2008

Natural secretion marks difference between mole and melanoma

A protein naturally produced and secreted by the body can make the difference between your average mole and melanoma, which killed more than 8,000 people in the United States last year, reveals a new study in the February 8 issue of the journal Cell, a publication of Cell Press.

8 Feb 2008

Discovery of protein that stops the growth of melanomas

One might call it a tale of two melanocytes. Given the same genetic mutation, why does one melanocyte shut down growth and become a relatively benign mole, while another rages out of control and develops into deadly melanoma"

8 Feb 2008

New insights into Legionella pneumophila

A study published online in Genome Research (www.genome.org) describes new insights into Legionella pneumophila, the bacteria responsible for most cases of Legionnaires' disease.

7 Feb 2008

Disrupted genetic regulation causes common disturbance in metabolism of fat

The disease familial combined hyperlipidemia (FCH) is a common cause of disturbed metabolism of fat and early heart attacks.

7 Feb 2008

Disrupted genetic regulation causes common disturbance in metabolism of fat

The disease familial combined hyperlipidemia (FCH) is a common cause of disturbed metabolism of fat and early heart attacks.

5 Feb 2008

Study of successful drug targets could hasten development of new medications

Guidance from an innovative computational approach could speed up the process and cut down the cost of new drug development, researchers from the University of Chicago Medical Center and Columbia University suggest in a study to be published in the February 2008 issue of Genome Research, available early online.

5 Feb 2008