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Combination of blood pressure-lowering drugs stops loss of kidney function in rare genetic disease

A combination of two types of blood pressure-lowering drugs, an angiotensin-converting enzyme inhibitor (ACEI) plus an angiotensin-receptor blocker (ARB), added to enzyme replacement therapy (ERT) with agalsidase-beta (Fabrazyme, Genzyme Corporation, Cambridge, MA) is the first treatment shown to stop progressive loss of kidney function in patients with severe kidney involvement due to the rare genetic disorder Fabry disease, reports a study in the September Journal of the American Society of Nephrology.

26 Jul 2007

The future of Alzheimer's disease research

Imagine the day when a routine visit to the family doctor includes a simple blood test to predict the risk for developing Alzheimer's disease (AD).

26 Jul 2007

Itchy and scratchy gene discovered

Itching for a better anti-itch remedy? Your wish may soon be granted now that scientists at Washington University School of Medicine in St. Louis have identified the first gene for the itch sensation in the central nervous system.

26 Jul 2007

Link between breast cancer and hormone therapy confirmed

A sharp drop in breast cancer rates from 2003 to 2004 is linked to an even larger drop in women's use of hormone therapy that began around 2000, according to a Kaiser Permanente study in the August 1, 2007, issue of the Journal of the National Cancer Institute that confirms the connection between breast cancer, hormone therapy and mammography screening over the past 25 years.

25 Jul 2007

Faster-acting antidepressant medications

A new study has revealed more about how the medication ketamine, when used experimentally for depression, relieves symptoms of the disorder in hours instead of the weeks or months it takes for current antidepressants to work.

25 Jul 2007

Breast cancer and HRT

The medical community has been debating for many years whether, and to what extent, postmenopausal hormone therapy (HT) use is associated with a higher risk of breast cancer, says Professor Amos Pines, President of the International Menopause Society.

25 Jul 2007

Initiative to improve heart failure care at nation's hospitals makes major gains

A national initiative designed to improve heart-failure patient care in hospitals proved effective at increasing hospital adherence to key quality-of-care performance measures and reducing the length of hospital stays for patients.

24 Jul 2007

Nicotine rush hinges on sugar in neurons

As with other questions involving good sensations, the answer appears to be sugar.

23 Jul 2007

Group therapy does not prolong the lives of women with metastatic breast cancer

Earlier results from the same researcher had suggested a survival benefit of group therapy for women with metastatic breast cancer. However, the new study did find that women with estrogen receptor (ER) negative tumors did show survival benefit, and that group therapy improved quality of life (QOL).

23 Jul 2007

Good diet + exercise = less insulin in the brain and a longer life!

Scientists in the U.S. say reducing the action of insulin in the brain could well be the secret to longevity.

22 Jul 2007

Schering-Plough announces licensing of Acadesine

Schering-Plough Corporation has announced the worldwide licensing of acadesine, an investigational, potentially first-in-class adenosine regulating agent (ARA), from PeriCor Therapeutics, Inc., a privately held, specialty biopharmaceutical company.

20 Jul 2007

New biochemical mechanism for memory storage

Our experiences - the things we see, hear, or do - can trigger long-term changes in the strength of the connections between nerve cells in our brain, and these persistent changes are how the brain encodes information as memory.

20 Jul 2007

Eat a good diet and exercise to live longer

The traditional prescriptions for a healthy life sensible diet, exercise and weight control extend life by reducing signaling through a specific pathway in the brain, according to Howard Hughes Medical Institute researchers who discovered the connection while studying long-lived mice.

20 Jul 2007

Critical link found between two proteins found in brain tumors

MIT researchers have identified a critical link between two proteins found in brain tumors, a discovery that could eventually help treat a form of brain cancer that kills 99 percent of patients.

20 Jul 2007

Genetic variation linked to premenstrual depression

A specific genetic variation may be tied to an increased risk for severe premenstrual depression, scientists at the University of North Carolina at Chapel Hill and the National Institute of Mental Health have found.

18 Jul 2007

Role prefrontal cortex plays in memory

A research with experimental rats carried out by the Institute of Neuroscience of the UAB describes the brain region connected to how our declarative memory functions.

18 Jul 2007

Quitting smoking with rimonabant

Using selective cannabinoid 1 (CB1) receptor antagonists such as rimonabant at a dose of 20 mg per day can help people quit smoking, can help them to remain abstinent, and can help prevent the weight gain that so often accompanies attempts at stopping smoking.

18 Jul 2007