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Evolving complexity out of junk DNA

The study, published in Proceedings of the National Academy of Sciences, USA, claims to have solved this scientific riddle by analysing the genomics of primitive living fishes such as sharks and lampreys and their spineless relatives, such as the sea squirts.

12 Feb 2008

Beginnings of complex life traced to microRNA

Dartmouth College researchers and colleagues from the University of Bristol in the U.K. have traced the beginnings of complex life, i.e. vertebrates, to microRNA.

12 Feb 2008

Moss protein plays role in Alzheimer's disease

Preventing Alzheimer's from developing is a goal of Raphael Kopan, Ph.D., professor of molecular biology and pharmacology at the Washington University School of Medicine.

11 Feb 2008

Seven new prostate cancer genetic risk factors identified

Cancer Research UK funded scientists have found seven new sites in the human genome that are linked to men's risk of developing prostate cancer. Their findings are published in Nature Genetics today.

11 Feb 2008

Revelation of new genes linked to prostate cancer could single out high risk men

The discovery by researchers of at least ten new genes associated with prostate cancer could in future be used to accurately identify high-risk men.

11 Feb 2008

Scientists reveal a new target to fight bad cholesterol

Scientists have uncovered a new region in the genome that is responsible for the body's ability to regulate bad cholesterol which is linked to heart attack and stroke.

8 Feb 2008

Researchers decode genetics of chlorophyll d

A bacterium that harvests far-red light by making a rare form of chlorophyll (chlorophyll d) has revealed its genetic secrets, according to a team of researchers who recently sequenced the bacteria's genome.

8 Feb 2008

Scientists find how PARP-1 protein binds to genes and regulates human genome

Out of chaos, control: Cornell University molecular biologists have discovered how a protein called PARP-1 binds to genes and regulates their expression across the human genome.

8 Feb 2008

Natural secretion marks difference between mole and melanoma

A protein naturally produced and secreted by the body can make the difference between your average mole and melanoma, which killed more than 8,000 people in the United States last year, reveals a new study in the February 8 issue of the journal Cell, a publication of Cell Press.

8 Feb 2008

Discovery of protein that stops the growth of melanomas

One might call it a tale of two melanocytes. Given the same genetic mutation, why does one melanocyte shut down growth and become a relatively benign mole, while another rages out of control and develops into deadly melanoma"

8 Feb 2008

New insights into Legionella pneumophila

A study published online in Genome Research (www.genome.org) describes new insights into Legionella pneumophila, the bacteria responsible for most cases of Legionnaires' disease.

7 Feb 2008

Disrupted genetic regulation causes common disturbance in metabolism of fat

The disease familial combined hyperlipidemia (FCH) is a common cause of disturbed metabolism of fat and early heart attacks.

7 Feb 2008

Disrupted genetic regulation causes common disturbance in metabolism of fat

The disease familial combined hyperlipidemia (FCH) is a common cause of disturbed metabolism of fat and early heart attacks.

5 Feb 2008

Study of successful drug targets could hasten development of new medications

Guidance from an innovative computational approach could speed up the process and cut down the cost of new drug development, researchers from the University of Chicago Medical Center and Columbia University suggest in a study to be published in the February 2008 issue of Genome Research, available early online.

5 Feb 2008

New research shows that people with blue eyes have a single, common ancestor

A team at the University of Copenhagen have tracked down a genetic mutation which took place 6-10,000 years ago and is the cause of the eye colour of all blue-eyed humans alive on the planet today.

4 Feb 2008

Variation in the BCL11A gene linked to moderated symptoms of beta-thalassemia

Beta-thalassemia is a serious, potentially life-threatening disease that affects red blood cells, cells that carry oxygen via hemoglobin throughout the body.

4 Feb 2008

Viruses for a healthy pregnancy

Sequences of DNA in the human genome that originated from ancient viral infections have some surprising effects on our bodies and are even essential for a healthy pregnancy, according to an article in the February issue of Microbiology Today.

31 Jan 2008

Discovery of novel molecular pattern linked to colon cancer prognosis

An international research team has identified a link between the expression patterns of a class of molecules called microRNAs and how a patient's colon cancer may progress.

29 Jan 2008

Search for the 'on' switches may reveal genetic role in development and disease

A new resource that identifies regions of the human genome that regulate gene expression may help scientists learn about and develop treatments for a number of human diseases, according to researchers at Duke's Institute for Genome Sciences & Policy (IGSP).

25 Jan 2008

Celebrex may disrupt heart rhythm

Celebrex, a popular arthritis drug that blocks pain by inhibiting an enzyme known as COX-2, has been shown in laboratory studies to induce arrhythmia, or irregular beating of the heart, via a novel pathway unrelated to its COX-2 inhibition.

25 Jan 2008