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Dual action of genes and RNA influences aggressive triple-negative breast cancer

Women with an aggressive, less-common type of breast cancer, known as triple-negative, versus a more common form of the disease, could be differentiated from each other by a panel of 17 small RNA molecules that are directly influenced by genetic alterations typically found in cancer cells.

22 Oct 2019

High glucose impairs circadian clock function, may increase cardiovascular risk

High glucose in obesity appears to gum up the works of the circadian clocks inside our cells that help regulate the timing of many body functions across the 24-hour day and drive the risk of cardiovascular disease, scientists say.

22 Oct 2019

IBD far more common than expected, and will only increase in future

There are three times as many people with the chronic and debilitating bowel disorder called inflammatory bowel disease (IBD) as ever thought before, according to a new study presented today at UEG Week 2019, at Barcelona. Not only is the condition a distressing one in itself, but patients with IBD have a higher risk of colorectal cancer as well.

21 Oct 2019

Antibiotic resistance doubles in just two decades

Antibiotic resistance poses a grave challenge to many previously curable infectious diseases. At present, antibiotic resistance is proving to increase at a much faster rate compared to the development of new therapies.

21 Oct 2019

Good heart health can equal good brain health, study shows

Emory University researchers are giving us double the reasons to pay attention to our cardiovascular health - showing in a recently published study in the Journal of Alzheimer's Disease that good heart health can equal good brain health.

21 Oct 2019

Link found between genetic variations and size of the brainstem, other subcortical structures

Researchers have found a link between 48 common genetic variations and the size of the brainstem and other subcortical structures deep within the brain.

21 Oct 2019

Discovery about DNA-reeling bacteria can help inform strategies to stop bacterial infection

A new study from Indiana University has revealed a previously unknown role a protein plays in helping bacteria reel in DNA in their environment -- like a fisherman pulling up a catch from the ocean.

21 Oct 2019

Pluripotent stem cells help advance understanding of how Huntington's disease develops

Huntington's disease (HD) is a fatal hereditary disease for which there is no cure. A novel study from Cedars-Sinai Medical Center, Los Angeles, using pluripotent stem cells advances understanding of how the disease develops and may help pave the way for identifying pathways for future treatments.

21 Oct 2019

Machine learning algorithm effectively identifies individuals with probable familial hypercholesterolemia

The FH Foundation, a leading research and advocacy organization, announced today that a machine learning algorithm effectively identified individuals with probable familial hypercholesterolemia (FH) for the first time at a national scale through its FIND FH initiative.

21 Oct 2019

Simple blood test can better identify patients at risk of relapse for B-cell lymphoma

Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma, a cancer that begins in certain immune system cells and can occur almost anywhere in the body. More than 28,000 people are diagnosed with DLBCL each year.

21 Oct 2019

Salk scientists receive NIH funding to map brain circuitry for movement

A team of Salk scientists led by Professor Martyn Goulding has been awarded $14.3 million over five years by the National Institutes of Health to create a high-resolution atlas of how the mouse brain generates and controls skilled forelimb movements, such as reaching and grasping.

18 Oct 2019

NCATS funds 'All of Us Research Program' to evaluate innovative DNA sequencing tools

The All of Us Research Program has selected the HudsonAlpha Institute for Biotechnology, Huntsville, Alabama, to evaluate the use of leading-edge DNA sequencing technologies that could someday improve diagnosis and treatment of many diseases, both common and rare.

18 Oct 2019

Researchers identify compound effective in killing chemotherapy-resistant cancer cells

A compound effective in killing chemotherapy-resistant glioblastoma-initiating cells has been identified, raising hopes of producing drugs capable of eradicating refractory tumors with low toxicity.

18 Oct 2019

Does bipolar disorder increase the risk of Parkinson's disease?

A review published by the JAMA Network has found that the risk of Parkinson's disease is significantly higher in those with bipolar disorder.

18 Oct 2019

Researchers uncover novel molecular clues for tumor aggression in neurofibromatosis type 1

Researchers at the Johns Hopkins Kimmel Cancer Center report that their study of tumor samples from people with the rare genetic syndrome neurofibromatosis type 1 (NF1) has uncovered novel molecular clues about which tumors are most likely to be aggressive in those with NF1

From Johns Hopkins Medicine 18 Oct 2019

Genetic News and Research

Dual action of genes and RNA influences aggressive triple-negative breast cancer

High glucose impairs circadian clock function, may increase cardiovascular risk

IBD far more common than expected, and will only increase in future

Antibiotic resistance doubles in just two decades

Good heart health can equal good brain health, study shows

Link found between genetic variations and size of the brainstem, other subcortical structures

Discovery about DNA-reeling bacteria can help inform strategies to stop bacterial infection

Pluripotent stem cells help advance understanding of how Huntington's disease develops

Machine learning algorithm effectively identifies individuals with probable familial hypercholesterolemia

Simple blood test can better identify patients at risk of relapse for B-cell lymphoma

Salk scientists receive NIH funding to map brain circuitry for movement

NCATS funds 'All of Us Research Program' to evaluate innovative DNA sequencing tools

Researchers identify compound effective in killing chemotherapy-resistant cancer cells

Does bipolar disorder increase the risk of Parkinson's disease?

Researchers uncover novel molecular clues for tumor aggression in neurofibromatosis type 1

Yale scientists build powerful genomic research platform to study cervical cancer

New research center will encompass a myriad of muscle science and disease investigations

Adding plant-based compound to gene therapy could improve treatment outcomes

Study shows link between high-fat diet and earlier appearance of Alzheimer's markers in the brain

Researchers analyze neurodegeneration linked to FXTAS by measuring motor behavior

Genetics & Genomics - Second Edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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