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Modified form of poliovirus shows potential as cancer vaccine in animal studies

A modified form of poliovirus, pioneered at Duke Cancer Institute as a therapy for glioblastoma brain tumors, appears in laboratory studies to also have applicability for pediatric brain tumors when used as part of a cancer vaccine.

31 Jan 2020

Cooling burns with running water is the best initial treatment, study reveals

New research in the January edition of Annals of Emergency Medicine reveals that cooling with running water is the best initial treatment for a child's burn.

30 Jan 2020

Turning stink into therapy for atherosclerosis

In an amusing but amazing turnaround, it seems the most foul-smelling compound on earth, called putrescine, could help relieve chronic inflammation, most importantly in the arterial thickening called atherosclerosis. This discovery is reported in the journal Cell Metabolism in January 2020.

30 Jan 2020

Gene-editing taken to advanced levels in human stem cells

A new study published in the journal Stem Cell Reports in January 2020 reports the use of an adaptation to a commonly used gene editing technology to achieve a more than 900% increase in efficiency.

30 Jan 2020

Scientists reveal clinical features of Wuhan coronavirus patients

The Wuhan coronavirus, or the 2019-nCoV, which originated in Wuhan City in Hubei province infected more than 7,700 people with the death toll topping more than 170. China reports 38 deaths in just 24 hours, making the outbreak one of the deadliest ones the country has faced.

30 Jan 2020

$18 million gift will support UCLA's expansion of integrative psychosocial cancer care

An $18 million commitment from the Simms/Mann Family Foundation, led by Dr. Victoria Mann Simms and Ronald Simms, will support UCLA's expansion of integrative psychosocial care for people with cancer and their families into communities throughout Southern California.

30 Jan 2020

Less chemotherapy may be equally or even more beneficial to rectal cancer patients

Chemotherapy used to shrink a tumor before surgery, called neoadjuvant chemotherapy, is becoming more common in many cancers, including stage II and III rectal cancer.

30 Jan 2020

New research could lead to 'breakthrough' for myelodysplastic syndrome

Korean researchers have observed cup-shaped red blood cells in the peripheral blood of a patient with myelodysplastic syndrome.

From Tomocube Inc. 30 Jan 2020

Death receptor pathway drives resistance to CAR T cell therapy

Some cancer cells refuse to die, even in the face of powerful cellular immunotherapies like CAR T cell therapy, and new research from the Abramson Cancer Center of the University of Pennsylvania is shedding light on why.

30 Jan 2020

New target protein linked to regulation, movement of tumor-associated macrophages

Developing a therapy to combat cancer remains one of the most difficult challenges in medical research. Cancer owes its notorious identity to the fact that the cancer cells use the host's own immune system to grow and spread, ultimately becoming deadly.

30 Jan 2020

Study may help develop ibrutinib-based combination therapies for blood cancer

Chronic lymphocytic leukemia (CLL) is the most common form of blood cancer (leukemia) in the Western world, affecting approximately 1.2% of all cancer patients.

30 Jan 2020

Novel inhibitor to fight metastatic prostate cancer shows promise

When prostate cancer spreads it is often a deadly disease, but now a Stony Brook University-led research team believes a new approach that inhibits a specific fatty acid binding protein (FABP) may be the key to halting disease progression.

30 Jan 2020

Research reveals key molecular target for colorectal cancer therapy

Serine racemase is a multifunctional enzyme that carries out several different reactions in human cells, including the conversion of L-serine into pyruvate.

29 Jan 2020

Researchers develop first non-invasive way to monitor oxygen in tumors during radiation therapy

Oxygen in cancer tumors is known to be a major factor that helps radiation therapy be successful. Hypoxia, or starvation of oxygen, in solid tumors is also thought to be an important factor in resistance to therapy.

29 Jan 2020

Bandages sense infections, change color, treat infection

In what reads like science fiction, a new study published in the journal ACS Central Science reports the development of bandages that detect the presence of bacteria in wounds and change color, depending on whether they are drug-sensitive or drug-resistant. This is an important step in helping patients recover better.

29 Jan 2020

Pre-existing anticancer drug could help treat common form of heart failure

When it comes to finding new treatments for disease, reinventing the wheel is not always necessary - drugs already in use for other conditions may do the job.

29 Jan 2020

A single dose of magic mushroom compound reduces anxiety and depression among cancer patients

Magic mushrooms are wild or cultivated mushrooms containing psilocybin, which is a naturally occurring hallucinogenic and psychoactive compound. A single dose of psilocybin provides long-term relief of anxiety and depression in cancer patients, a new study found.

29 Jan 2020

New way to treat stroke using an already FDA-approved drug shows promise

Stroke is the third leading cause of death and disability in the United States. More than 87 percent are ischemic strokes, caused by obstruction of one or more cerebral arteries. With limited progress in developing treatments, there is a critical need for neuroprotective agents to effectively treat stroke.

29 Jan 2020

High carbon dioxide levels due to respiratory diseases may aggravate pancreatic cancer

Chronic obstructive pulmonary disease or COPD is associated with higher rates of many cancers, including lung, esophagus, colon, bladder and breast cancer.

29 Jan 2020

Time to include standard care screenings for diagnosis of pre-symptomatic type 1 diabetes

Researchers at Helmholtz Zentrum München employed the world's first early detection test for type 1 diabetes in a large-scale population study in Bavaria, Germany, and investigated its effects.

29 Jan 2020