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New database of 14,000 known macrolactones could support drug discovery and research

Researchers from North Carolina State University and Collaborations Pharmaceuticals have created a free-to-use database of 14,000 known macrolactones - large molecules used in drug development - which contains information about the molecular characteristics, chemical diversity and biological activities of this structural class.

22 Apr 2020

Analysis reveals cocktail of pharmaceuticals in the waters of Bangladesh

In spring of 2019, researchers set out to investigate what chemicals could be found in the waters of Bangladesh.

20 Apr 2020

Inhibition of sphingolipid metabolism and neurodegenerative diseases

Disrupting production of sphingolipids in neurons improved neurodegeneration symptoms and increased survival in a mouse model.

13 Apr 2020

Study: Bangladesh’s surface waters have high levels of antibiotic residues, chemicals

High levels of antibiotic residues, other medicines and chemicals present in Bangladesh's ponds, canals, lakes, rivers and other surface waters are contributing to a spike in antibiotic resistance in the country, says a new study.

11 Apr 2020

Research findings could aid in the recognition and management of COVID-19 pneumonia

Researchers have identified the most common clinical characteristics of 109 patients with COVID-19 related pneumonia who died in Wuhan, China in the early stages of the coronavirus pandemic, according to a new study published online in the Annals of the American Thoracic Society.

7 Apr 2020

Researchers make breakthrough in unlocking genetic potential of ocean microbes

Researchers have made a breakthrough in developing gene-editing tools to improve understanding of an important ocean microbe.

6 Apr 2020

How cannabis interacts with medications

A new practice guideline published in the journal CMAJ in February 2020 describes five types of drug interactions possible with the use of cannabis. Cannabis is a plant-derived drug containing the psychoactive ingredient delta-9-tetrahydrocannabinol (THC) and non-psychoactive cannabidiol (CBD). These cannabinoids are broken down by the liver enzymes cytochrome P450 C(YP)34A, and CYP2CC9.

2 Mar 2020

Five things to know about drug interactions with cannabinoids

A practice article provides 5 things to know on how drugs can interact with cannabinoids in CMAJ.

2 Mar 2020

Study finds significant increase in skin allergy to 'bee glue'

Skin allergy to an ingredient found in many natural skin products has more than doubled since 2007, according to a study in the British Journal of Dermatology.

28 Feb 2020

Metal complexes could hold the key to next generation of antibiotics

Compounds containing metals could hold the key to the next generation of antibiotics to combat the growing threat of global antibiotic resistance.

27 Feb 2020

Essential oil components could meet the criteria set for drug candidates

A research team at the VIB-KU Leuven Center for Microbiology and the KU Leuven Department of Biology showed that, contrary to generally held belief, most components of essential oils could meet the criteria set for drug candidates.

23 Feb 2020

Swansea University drug resistance research highlighted in two prestigious journals

Swansea University research into the threat posed by antifungal drug resistance has been highlighted in two prestigious international journals.

14 Feb 2020

Acid reflux drug may be a promising therapy to reduce preterm birth

Lansoprazole, an over-the-counter acid reflux drug that is often taken by pregnant women, may be a promising therapy to reduce preterm birth, according to a computational drug repurposing study that also tested several of the drugs in mice.

13 Feb 2020

Scientists discover potential drug compounds that target common type of liver cancer

Scientists from the Cancer Science Institute of Singapore at the National University of Singapore, and the Agency for Science, Technology and Research (A*STAR)'s Genome Institute of Singapore have discovered four potential drug compounds that target hepatocellular carcinoma, the most common type of liver cancer.

30 Dec 2019

Valley fever cases climb in California’s Central Valley — and beyond

Valley fever cases are on the rise in California and across the arid Southwest, and scientists point to climate change and population shifts as possible reasons.

17 Dec 2019

Yeasts derived from food can reduce multi-drug resistant fungal infections

A study by researchers in the United States and India has shown that probiotic yeasts derived from food are able to reduce the virulence of, and even prevent infections by, several types of fungi that are responsible for life-threatening infections in hospitalized and immune-compromised individuals, including the multi-drug resistant Candida auris, which was recently listed as an urgent threat by the U.S. Centers for Disease Control in its 2019 Antibiotic Resistance Threats report.

10 Dec 2019

Antifungal News and Research

New database of 14,000 known macrolactones could support drug discovery and research

Analysis reveals cocktail of pharmaceuticals in the waters of Bangladesh

Inhibition of sphingolipid metabolism and neurodegenerative diseases

Study: Bangladesh’s surface waters have high levels of antibiotic residues, chemicals

Research findings could aid in the recognition and management of COVID-19 pneumonia

Researchers make breakthrough in unlocking genetic potential of ocean microbes

How cannabis interacts with medications

Five things to know about drug interactions with cannabinoids

Study finds significant increase in skin allergy to 'bee glue'

Metal complexes could hold the key to next generation of antibiotics

Essential oil components could meet the criteria set for drug candidates

Swansea University drug resistance research highlighted in two prestigious journals

Acid reflux drug may be a promising therapy to reduce preterm birth

Scientists discover potential drug compounds that target common type of liver cancer

Valley fever cases climb in California’s Central Valley — and beyond

Yeasts derived from food can reduce multi-drug resistant fungal infections

Yale study highlights the need to develop effective, less toxic approaches to treat AML patients

Common first-line treatment for cryptococcal meningitis in being compromised by drug resistance

Common treatment for cryptococcal meningitis compromised by emergence of drug resistance

Failure to ensure environmental management of pharmaceuticals can lead to adverse outcomes

Revolutionizing Life Science: An Interview with SCIEX on ASMS, the SCIEX 7500+ System, and AI-Driven Quantitation

From Discovery Biology to ELRIG Chair

Breathing New Life into Diagnostics: Plasmion's SICRIT Technology

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