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Manganese-coordinated lipid nanoparticles boost VZV vaccine-induced T cell responses

Announcing a new article publication for Zoonoses journal. Because varicella zoster virus (VZV) infections are continually increasing, vaccine efficacy must be enhanced.

10 Jun 2025

COVID boosters do not harm T-cell function in the vulnerable

Findings indicate that frequent COVID-19 booster shots do not weaken T-cell responses, alleviating concerns for vulnerable groups facing new variants.

9 Jun 2025

Engineered viruses and gene therapy halt tumor growth and extend survival in mice

This study reveals the potential of engineered phage-IL-12 therapy in melanoma, enhancing immune response and tumor destruction in aggressive cancer models.

2 Jun 2025

New electrochemical device advances point-of-care HIV diagnostics

Accurate monitoring of CD4+ T cell counts is vital for evaluating immune health and guiding treatment in people living with Human Immunodeficiency Virus (HIV).

30 May 2025

Scientists make major progress toward an effective HIV vaccine

In the long battle to create an effective HIV vaccine, scientists have made a major leap forward. A new study shows that a series of vaccines can coax the immune system to produce powerful antibodies capable of blocking a wide range of HIV strains-including those that are typically the hardest to stop.

27 May 2025

Novel immune cells identified as potential target for tuberculosis vaccines

There is no highly effective vaccine against tuberculosis (TB), which remains an infection of global concern.

26 May 2025

New discovery may help explain why some people infected with CHIKV develop severe joint pain

Chikungunya virus (CHIKV) is a mosquito-borne pathogen that has been identified in more than 110 countries around the world. The virus typically causes flu-like symptoms, but it can also trigger chronic, severe joint pain in some people.

20 May 2025

HIV uses circular RNAs to evade immunity and boost replication

In a groundbreaking discovery, researchers from Florida Atlantic University's Charles E. Schmidt College of Medicine have identified a never-before-seen mechanism that enables the human immunodeficiency type 1 virus (HIV-1) to evade the body's natural defenses and use it to support its survival and replication.

13 May 2025

Nasal vaccine boosters can trigger strong immune defenses in the respiratory tract, study finds

Most vaccines — and boosters — are injected directly into muscle tissue, usually in the upper arm, to kickstart the body's immune system in the fight against disease.

13 May 2025

Nectin4-targeted VHH-CAR-T cells show potency against bladder cancer

Announcing a new article publication for BIO Integration journal. Bladder cancer (BLCA) is one of the most common malignancies and the second most frequent urogenital tract tumor.

29 Apr 2025

How immune resilience and salutogenesis promote disease resistance and longevity

Researchers examine how salutogenesis, the active production of health through immune resilience, resists disease.

28 Apr 2025

Immune system selects the best T cells for targeted defense

The research groups led by Wolfgang Kastenmüller and Georg Gasteiger employed innovative microscopy techniques to observe how specific immune cells, known as T-cells, are activated and proliferate during a viral infection.

10 Apr 2025

Refining the diagnosis of large granular lymphocytic leukemias and their mimics

Large granular lymphocytic leukemias (LGLLs) are a heterogeneous group of rare chronic lymphoproliferative disorders characterized by the clonal proliferation of cytotoxic lymphocytes. Among them, T-cell LGLL (T-LGLL) and NK-cell LGLL (NK-LGLL) are the most prominent.

10 Apr 2025

High fiber diet helps protect against dangerous gut infections

A study published in the journal Cell Host & Microbe by Brazilian and American researchers suggests that a diet rich in soluble fiber can protect the intestine against pathogenic bacteria.

9 Apr 2025

Enhanced tuberculosis detection in advanced HIV using stool molecular testing

The Xpert MTB/Ultra molecular diagnostic test for stool samples, until now recommended only for children, could be established as an additional test for diagnosing tuberculosis in adults living with HIV.

4 Apr 2025

Study reveals key role of Treg cells in preventing autoimmune responses

During infections, the immune system needs to distinguish foreign antigens that are expressed by invading bacteria and viruses from self-antigens that are expressed by cells of the body.

22 Mar 2025

Circadian rhythms play a crucial role of in regulating tumor progression

Circadian rhythms are endogenous time-keeping mechanisms that regulate physiological processes in response to external light-dark cycles.

21 Mar 2025

Semi-synthetic bile acid could be a promising therapeutic option for TH17-mediated intestinal diseases

A research team from the Medical University of Vienna has made further progress in the treatment of intestinal inflammation.

14 Mar 2025

ViiV Healthcare’s investigational broadly neutralising antibody - N6LS - successfully maintains viral suppression in long-acting treatment of HIV

ViiV Healthcare, the global specialist HIV company majority owned by GSK, with Pfizer and Shionogi as shareholders, today announced positive findings from the company’s EMBRACE phase IIb study.

13 Mar 2025

Innovative AI-enabled, low-cost device makes flow cytometry accessible for clinical use

A team of researchers at the George R. Brown School of Engineering and Computing at Rice University has developed an innovative artificial intelligence (AI)-enabled, low-cost device that will make flow cytometry ⎯ a technique used to analyze cells or particles in a fluid using a laser beam ⎯ affordable and accessible.

2 Mar 2025