Dopaminergic News and Research

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Parkinson's disease diagnosed after SARS-CoV-2

As the COVID-19 pandemic continues to spread, new and unusual chronic sequelae of the disease are cropping up in many medical practices. Now, a new case paper published in The Lancet in September 2020 describes a case of new-onset Parkinson's disease following infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

22 Sep 2020

Study links brain astrocyte dysfunction to Parkinson’s disease pathology

A new study using induced pluripotent stem cell technology links astrocyte dysfunction to Parkinson’s disease pathology.

8 Sep 2020

Potential link to brain inflammation may explain the connection between MS and fatigue

Up to 60 percent of patients with multiple sclerosis (MS) report that fatigue is the disease's most debilitating symptom.

27 Aug 2020

Journal Of Parkinson's Disease announces recipients of first Parkinson Prize

The Journal of Parkinson's Disease and its publisher IOS Press are proud to announce the two articles that have won the first Parkinson Prize, recognizing these outstanding contributions to the advancement to Parkinson's disease research.

23 Jul 2020

Dopaminergic neurones behave differently in different animals, shows study

Animals have an innate preference for certain scents and tastes. Attractive scents are linked to things like good food.

16 Jul 2020

Dopamine therapy improves cognitive function in patients with mild-to-moderate Alzheimer's

A study supported by the Alzheimer's Drug Discovery Foundation and published today in JAMA Network Open provides the first evidence that rotigotine, a drug that acts on dopamine transmission in the brain, improves cognitive function in patients with mild-to-moderate Alzheimer's disease.

15 Jul 2020

New model helps study human hippocampal neurons

Neuroscientists and stem cell researchers at Lund University in Sweden have developed a research model that allows studying human hippocampal neurons, the brain cells primarily affected by Alzheimer's disease pathology.

29 Jun 2020

Parkinson's disease breakthrough seen in mouse model

Researchers from the University of California San Diego School of Medicine have found a way to create new neurons in a mouse model of Parkinson's disease. The severely debilitating and progressive neurodegenerative disease, as of now, has no cure, and this breakthrough could help hundreds of thousands of patients with the condition feel experts.

25 Jun 2020

AFFiRiS AG announces results of phase 1 trial with PD01A in Parkinson's

AFFiRiS AG, a clinical-stage biotechnology company developing novel disease-modifying specific active immunotherapies (SAITs), today announced that detailed results of the phase 1 clinical program with its lead candidate PD01 in early Parkinson's disease (PD) patients were published in the peer-reviewed journal The Lancet Neurology.

18 Jun 2020

Study shows how a nervous system coordinates distinct behavioral outputs

For a nematode worm, a big lawn of the bacteria that it eats is a great place for it to disperse its eggs so that each hatchling can emerge into a nutritive environment.

11 Jun 2020

Experts debate over future Parkinson’s disease trial involving growth factors

Growth factors such as glial cell line-derived neurotrophic factor (GDNF) were initially thought to be exciting new treatments for Parkinson's disease (PD), but trials have been disappointing.

5 Jun 2020

Cells from the gut's nervous system found to be involved in Parkinson's disease

Researchers at Karolinska Institutet in Sweden and the University of North Carolina in the USA have mapped out the cell types behind various brain disorders.

27 Apr 2020

Study reveals potential therapeutic target for treating cocaine addiction

A new study explains how cocaine modifies functions in the brain revealing a potential target for therapies aimed at treating cocaine addiction.

22 Apr 2020

Experts highlight the impact of COVID-19 pandemic on patients with Parkinson’s disease

While much attention has focused on the potential for severe respiratory complications and unfavorable outcomes from the COVID-19 pandemic among patients with Parkinson's disease (PD), the impact extends beyond these threats.

5 Apr 2020

MRI sensor reveals how dopamine drives brain activity

Using a specialized magnetic resonance imaging (MRI) sensor, MIT neuroscientists have discovered how dopamine released deep within the brain influences both nearby and distant brain regions.

1 Apr 2020

Zebrafish can provide genetic clues to human nicotine addiction

Researchers at Queen Mary University of London have shown that zebrafish can provide genetic clues to smoking, a complex human behavior.

30 Mar 2020

Study finds promising biomarker for diagnosis of schizophrenia and treatment response

Around four in a thousand people worldwide suffer from schizophrenia, according to scientific estimates. The disease affects people from all walks of life, including Vincent van Gogh, the painter Agnes Martin, mathematician John Nash and Eduard Einstein, a son of the great physicist. The disease touches men and women equally.

23 Mar 2020

Light-activated protein restores mitochondrion function in fruit fly model of Parkinson’s disease

A light-sensitive protein can restore mitochondria function in fruit flies bearing a gene mutation associated with Parkinson’s disease and relieve its symptoms, report researchers at Juntendo University in the journal Communications Biology.

13 Feb 2020

Study suggests prenatal origin for ‘young’ Parkinson’s disease

A new study published in the journal Nature Medicine on January 2020 suggests that Parkinson’s disease developing before the age of 50 years could be due to an abnormality in certain brain cells that remains dormant until the age of onset of the disease. It also indicates the potential usefulness of a specific drug to prevent this by correcting the brain cell disorder.

27 Jan 2020

Potential Parkinson's treatment effectively targets a specific group of brain cells

Scientists have discovered that a non-invasive technique which could one day be used to treat Parkinson's disease, can successfully target a highly specific group of brain cells which play a key role in development of the condition.

22 Jan 2020