Encephalopathy News and Research

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Lario Therapeutics receives “Company Making a Difference Award” from CDLK5 Forum, recognising its unique approach to precision medicine for genetic epilepsies

“CDLK5 Forum Award for Excellence - Company Making a Difference 2023 Pre-clinical” presented by the Loulou Foundation at the CDKL5 Forum, 6th-7th November in London

7 Nov 2023

New analysis debunks myth: NFL players don't live longer, especially linemen

This study challenges the notion that American football players live longer by examining factors like education, health, and socioeconomic status. The research finds that linemen have a shorter life expectancy compared to players in other positions and men with similar backgrounds.

31 Oct 2023

Brain autopsy study of intimate partner violence victims shows extensive brain damage

The largest brain autopsy study of women who had experienced intimate partner violence reveals substantial vascular and white matter damage in the brain, but no evidence of chronic traumatic encephalopathy (CTE), the neurodegenerative disease recognized among male contact sports athletes who sustain repeated head trauma.

30 Oct 2023

A novel drug reduces the monthly frequency of seizure in adults with focal epilepsy

The effect of a novel Kv7.2/Kv7.3 potassium channel opener XEN1101 in reducing monthly seizure frequency in adults.

11 Oct 2023

Experts caution about unverified CTE diagnoses in former football players

Former professional American football players who have medical and mental health conditions including depression, anxiety or sleep apnea are more likely to receive an unverified diagnosis of chronic traumatic encephalopathy, or CTE, compared to those without those conditions, report researchers from the University of Pittsburgh School of Medicine, Harvard University and Vanderbilt University Medical Center in Sports Medicine today.

6 Oct 2023

Examining the cardiac pathology in fatal cases of yellow fever

The characteristics of yellow fever (YF)-related myocardial damage.

28 Sep 2023

Decoding tauopathies: New study identifies non-coding RNA as a key player in Alzheimer's

Researchers at Washington University School of Medicine identify a key step in the development of harmful tau tangles, offering a potential target for preventing brain damage in diseases like Alzheimer's. The study highlights the role of long noncoding RNAs, particularly SNHG8, in stress granule formation and tau aggregation, opening new avenues for treatment.

22 Sep 2023

COVID-19 hits American Indian and Alaska Native populations hardest, new study reveals

A recent study at the University of New Mexico Hospital highlights that American Indian and Alaska Native populations face disproportionate severity and mortality rates from COVID-19. The research points to the urgent need for targeted interventions and resources to address these health disparities.

5 Sep 2023

What are the neuropathologic and clinical findings in a convenience sample of young, deceased, symptomatic contact sport athletes?

Researchers characterized the neuropathological and clinical symptoms of chronic traumatic encephalopathy among young brain donors exposed to repetitive head impacts.

30 Aug 2023

High cost of hepatic encephalopathy treatment may lead to medication non-adherence

Researchers from the University of Minnesota Medical School and College of Pharmacy have found that high costs for hepatic encephalopathy treatment in patients with end-stage liver disease were associated with decreased treatment retention for patients.

25 Aug 2023

A pilot cohort study on infants with new-onset epilepsy examines the clinical utility of rapid genome sequencing

The clinical impact of rapid genome sequencing of infants with new-onset epilepsy.

22 Aug 2023

Football players at increased risk for Parkinson's disease, study finds

Identification of risk factors for Parkinson's disease (PD) is essential for early diagnosis. Dating back to the 1920s, Parkinson's disease and parkinsonism - an umbrella term that refers to motor symptoms found in Parkinson's disease and also other conditions - have long been described in boxers.

11 Aug 2023

New digital headset could help athletes return to play after concussion

A new digital headset designed to measure alterations in brain function could change decisions about how quickly an athlete is ready to return to play after a concussion.

11 Aug 2023

Penn Medicine researchers identify new therapeutic target for Alzheimer's disease

A gene encoding a protein linked to tau production - tripartite motif protein 11 (TRIM11) - was found to suppress deterioration in small animal models of neurodegenerative diseases similar to Alzheimer's disease (AD), while improving cognitive and motor abilities, according to new research from the Perelman School of Medicine at the University of Pennsylvania.

27 Jul 2023

Is repetitive heading of the ball during a professional soccer career associated with an increased risk of cognitive impairment?

In a recent study, a group of researchers investigated if heading frequency is associated with cognitive impairment in retired soccer players.

20 Jul 2023

New method improves prediction of liver disease progression

A research team from the Department of Medicine III at MedUni Vienna and University Hospital Vienna has conducted a large-scale study showing the important value of repeated liver assessments by a novel method that can significantly improve risk assessment in patients with chronic liver disease.

17 Jul 2023

PET scan not effective in diagnosing chronic traumatic encephalopathy in former NFL players, study finds

A new study showed that positron emission tomography (PET) with the radiotracer (18F)-Flortaucipir (FTP) to detect hyperphosphorylated Tau (p-tau) may not be appropriate for diagnosing chronic traumatic encephalopathy (CTE) neuropathologic changes in former professional American-style football players.

5 Jul 2023

New study reveals alarming cognitive impairments in long COVID patients

Persistent COVID-19 symptoms can lead to cognitive deficits in recovered patients. This systematic review highlights the need for further research and interventions to address long-term cognitive impairments.

28 Jun 2023

Football players at risk for CTE based on cumulative force of head hits, study shows

For years, researchers studying chronic traumatic encephalopathy, or CTE, believed the primary cause of it was repetitive hits to the head, whether or not those hits caused concussions.

23 Jun 2023

Research finds link between biomarkers in vitreous humor of the eye and Alzheimer's disease

New research from Boston Medical Center found a significant correlation between biomarkers in the vitreous humor of the eye and pathologically confirmed cases of Alzheimer's disease (AD) and Chronic Traumatic Encephalopathy (CTE) in post-mortem brain and eye tissue.

16 Jun 2023