Induced Pluripotent Stem Cells News and Research

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Stem cell treatment reduced deaths related to cardiovascular issues, not hospitalization

Stem cell therapy helped to reduce the number of heart attacks, strokes and death among people with chronic, high-risk, NYHA class II or III heart failure with reduced ejection fraction (HFrEF), especially among those who have higher levels of inflammation, yet hospitalization was not reduced, according to late-breaking research presented today at the American Heart Association's Scientific Sessions 2021.

15 Nov 2021

New evidence that SARS-CoV-2 virus can infect the inner ear

Many Covid-19 patients have reported symptoms affecting the ears, including hearing loss and tinnitus. Dizziness and balance problems can also occur, suggesting that the SARS-CoV-2 virus may be able to infect the inner ear.

29 Oct 2021

ioSkeletal Myocytes | New product launch

bit.bio has today launched a new product, ioSkeletal Myocytes.

From bit.bio 27 Oct 2021

Buck Institute receives $14 million NIH grant to focus on one of the major drivers of aging

Buck Institute professors Judith Campisi, PhD and Lisa Ellerby PhD, have been awarded a $14.3 million grant from the NIH's National Institute of Aging to study cellular senescence, one of the major hallmarks of aging, as a driver of Alzheimer's disease and other age-related dementias.

29 Sep 2021

Researchers create an integrated pipeline for performing genetic screening studies

Today's genetic engineers have a plethora of resources at their disposal: an ever-increasing number of massive datasets available online, highly precise gene editing tools like CRISPR, and cheap gene sequencing methods. But the proliferation of new technologies has not come with a clear roadmap to help researchers figure out which genes to target, which tools to use, and how to interpret their results. So, a team of scientists and engineers at Harvard's Wyss Institute for Biologically Inspired Engineering, Harvard Medical School (HMS), and the MIT Media Lab decided to make one.

28 Sep 2021

MMRI explores overlapping cardiac conditions as result of electrocution

It's not uncommon for people to live normal, healthy lives without knowledge of any underlying genetic conditions. However, all it takes is one external impact, such as a heart attack, to induce the expression of the condition.

22 Sep 2021

New model shows how dysfunction in the air sacs initiates fibrotic cascade

Idiopathic pulmonary fibrosis (IPF) is the most common and severe form of lung disease characterized by relentless scarring leading to death within an average of four years from the time of diagnosis.

31 Aug 2021

Researchers convert human stem cells into beta cells using small molecules

The human body can be genetically inclined to attack its own cells, destroying the beta cells in the pancreas that make insulin, which helps convert sugar into energy.

27 Aug 2021

Brain organoids provide a valuable model to study autism

Variations in the 16p11.2 region of the genome are associated with autism spectrum disorder. While people with genetic deletions in this region have larger heads (macrocephaly) and people with genetic duplications have smaller heads (microcephaly), both variation types affect brain development and function.

26 Aug 2021

CIRM approves a trio of awards for new stem cell-based projects

The governing Board of the California Institute for Regenerative Medicine has approved a trio of awards, totaling approximately $4 million, to University of California San Diego School of Medicine researchers to advance studies of new stem cell-based treatments for multiple types of cancer and amyotrophic lateral sclerosis (ALS).

25 Aug 2021

New discovery may lead to more effective treatments for osteoarthritis, other cartilage diseases

New information from a study reported on in STEM CELLS might result in more effective treatments for osteoarthritis and other cartilage diseases, as well as hereditary disorders affecting cartilage development.

25 Aug 2021

Researchers develop brain organoids that show neural activity similar to living human brains

Researchers at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have developed brain organoids -; 3D, brain-like structures grown from human stem cells -; that show organized waves of activity similar to those found in living human brains.

24 Aug 2021

Skin cells could provide better understanding of molecular mechanisms of frontotemporal dementia

A new study from the University of Eastern Finland suggests that skin fibroblasts from frontotemporal dementia patients may be useful in investigating underlying disease mechanisms as well as in biomarker and drug research.

12 Aug 2021

Researchers create new model for studying earliest stages of retinoblastoma

Scientists at St. JudeChildren's Research Hospital have created a laboratory model for studying retinoblastoma driven by inherited mutations in theRB1gene.Retinoblastoma is a rare cancer of the retina, the thin tissue inside the back of the eye.

6 Aug 2021

Mount Sinai researchers use cerebral organoids to study frontotemporal dementia

Frontotemporal dementias are a group of fatal and debilitating brain disorders for which there are no cures.

26 Jul 2021

Study shows promise of combining radiation therapy with dendritic-cell vaccines for breast cancer

A research team led by Fumito Ito, MD, PhD, FACS, of Roswell Park Comprehensive Cancer Center reports new data on the promise of combining standard treatment for breast cancer with a particular form of cancer immmunotherapy -; dendritic-cell (DC) treatment vaccines.

20 Jul 2021

Gene-edited cellular therapeutics can successfully treat cardiovascular and pulmonary diseases

Scientists at UC San Francisco have shown that gene-edited cellular therapeutics can be used to successfully treat cardiovascular and pulmonary diseases, potentially paving the way for developing less expensive cellular therapies to treat diseases for which there are currently few viable options.

6 Jul 2021

UB scientists publish a detailed guide for producing mature human cells in a mouse embryo

A year after University at Buffalo scientists demonstrated that it was possible to produce millions of mature human cells in a mouse embryo, they have published a detailed description of the method so that other laboratories can do it, too.

2 Jul 2021

Scientists discover genetic basis and molecular mechanisms of new neurodevelopmental syndrome

Scientists at the University of North Carolina at Chapel Hill School of Medicine and colleagues have demonstrated that variants in the SPTBN1 gene can alter neuronal architecture, dramatically affecting their function and leading to a rare, newly defined neurodevelopmental syndrome in children.

1 Jul 2021

Induced pluripotent stem cells hold great promise for regenerative medicine

The 2012 Nobel prize-winning discovery that ordinary cells could be coaxed to revert to their earliest pluripotent stage ushered in the era of ethical stem cell research.

28 Jun 2021