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Risk factors for cardiovascular-kidney-metabolic disease can be identified in young children

Risk factors for cardiovascular-kidney-metabolic disease, a health condition made up of heart disease, kidney disease, diabetes, and obesity, can be identified in children as young as 8, UTHealth Houston researchers discovered.

11 Sep 2026

Giant-nucleus cells form the foundation of early-stage cancer

Iron is an essential micronutrient, but excess iron can damage cells and increase cancer risk. While many cells die from iron-induced oxidative stress, a subset survives and may become cancerous.

11 Sep 2026

Proteomic signatures reveal early signs of cardiovascular-kidney-metabolic disease in children

Researchers at Vanderbilt Health, UTHealth Houston and the University of North Carolina at Chapel Hill have identified early signs of cardiovascular-kidney-metabolic disease (CKMD) in children as young as 8 years old that potentially can be reversed with a new class of weight loss drugs used widely by adults

11 Sep 2026

Healthy checkout ordinance linked to lower soda and candy sales

A new study found that a healthy checkout ordinance implemented in Berkeley, Calif. supermarkets, drug stores, and mass-market retailers in 2021 was linked to notable decreases in soda sales overall and small-package candy in supermarkets, but greater enforcement of such policies is essential for sustained and meaningful public health benefit.

10 Sep 2026

Study reveals hidden DNA damage from childhood chemotherapy

The amount of DNA damage caused by certain chemotherapies used to effectively treat childhood cancer has been revealed, along with a hidden impact on the liver, paving the way for future research into new ways to mitigate these impacts.

10 Sep 2026

Innovative device improves real-time monitoring of donated lungs

More than three-quarters of donated lungs offered for transplantation are not used, according to the UK's National Institute for Health and Care Excellence, contributing to a chronic shortage of organs for patients with end-stage lung disease.

10 Sep 2026

Rituximab alters T-cell metabolism in patients with nephrotic syndrome

Nephrotic syndrome is caused when the filtering system in the kidneys is damaged, allowing large amounts of protein to leak into the urine.

10 Sep 2026

Symptomless liver condition linked to heart and kidney disease

A common liver condition thought to be harmless could be dramatically increasing the risk of heart disease, kidney failure and premature death, according to a new review led by University of Manchester and Northern Care Alliance NHS Foundation Trust researchers.

10 Sep 2026

Caloric restriction reduces genetic mutations across the mouse genome

Mutations are changes in the molecular "letters" that make up DNA, the genetic blueprint for cells. Mutations build up with age in every cell when DNA is damaged or when cells make mistakes in fixing or copying it.

9 Sep 2026

New project explores financial impact of chronic kidney disease

A new research project launched by Kidney Wales and Aston University will explore how living with chronic kidney disease affects people's financial wellbeing.

9 Sep 2026

Rice, seafood and water may help explain striking differences in metal exposure across US communities

Researchers compared urinary trace-metal profiles across 666 adults from six ethnic groups in three US cohorts, with up to 19 elements measured and paired serum measurements available for the Asian Indian MASALA cohort. Distinct metal patterns emerged across populations, with the findings suggesting that diet, drinking-water sources, regional hydrogeology, urban-rural conditions, smoking, and physiological handling may all contribute to differences in exposure profiles.

8 Sep 2026

JMIR Publications: Emerging health tech trends

JMIR Publications released three feature News and Perspectives articles this week, covering an emerging application of drone delivery, the implications of AI tools used in early education, the nascent field of cancer neurotech, and the future of consumer wearable devices.

4 Sep 2026

Researchers uncover how Atg2 drives autophagosome formation

Autophagy is an intracellular degradation mechanism in eukaryotes. The autophagosome, which encloses damaged or excess cellular material for degradation, is constructed from lipids supplied by the endoplasmic reticulum (ER), via the lipid transfer protein Atg2.

4 Sep 2026

Pig kidney xenotransplantation offers a bridge for patients awaiting human donor kidneys

In January 2026, Tim Andrews, who had received a genetically edited pig kidney in January 2025, became the recipient of a human kidney.

3 Sep 2026

As life expectancy rises, healthy aging is more important than ever

Global disease burden is shifting toward aging-related conditions as people live longer, with these diseases now representing the largest expected lifetime health burden for newborns across all income groups. Modeling suggests that reducing aging-related disease could produce unusually large and progressively greater gains in both longevity and healthy life expectancy because improvements in survival and health reinforce one another.

3 Sep 2026

Semaglutide extended lifespan in older female mice, but that was not the only finding

Late-life semaglutide treatment slowed age-related physiological decline, attenuated multiple molecular hallmarks of aging, and extended median lifespan from 742 to 834 days in aged female mice. The drug reproduced many effects of calorie restriction while providing additional benefits in exploratory behavior, spatial memory, and glucose control, suggesting that some effects extend beyond reduced calorie intake alone.

3 Sep 2026

Increasing Canadian wildfires jeopardize critical care for dialysis patients

In the midst of another intense wildfire season, a new study sheds light on the risks they pose to life-sustaining dialysis care for thousands of Canadians.

3 Sep 2026

Too little or too much testosterone may matter for heart rhythm

A review of clinical trials, observational studies, genetic analyses, and mechanistic research suggests that atrial fibrillation risk may follow a U-shaped relationship with testosterone, increasing at both low and high levels. Evidence on testosterone replacement therapy remains mixed, with researchers calling for prospective studies to determine whether mid-physiological testosterone targets and treatment formulation influence AF risk.

2 Sep 2026

AI learned from cardiologists’ notes, and needed far less labeled ECG data

By teaching an AI system to connect raw heart signals with the clinical insights contained in cardiologists’ reports, researchers tested whether routine ECGs could reveal more with far fewer labeled examples.

2 Sep 2026

ECG-CLIP improves heart disease detection using less labeled data

Clinicians often use a medical test called a 12-lead electrocardiogram (ECG) to diagnose heart problems, which uses electrodes placed on the chest and limbs to record the heart's electrical activity.

1 Sep 2026