Next generation sequencing NGS News and Research

RSS

Unexplored NGS data could help elucidate carcinogenesis and discover biomarkers

A new research perspective was published in Oncotarget's Volume 13 on November 17, 2022, entitled, "Treasures from trash in cancer research."

24 Nov 2022

Does a vasectomy change the semen microbiome?

Researchers investigate alterations in the semen microbiome before and after the vasectomy procedure.

22 Nov 2022

Scientists explore bat sarbecovirus isolation in Japan

Researchers performed bat sarbecovirus isolation experiments using Rhinolophus cornutus bats from several regions in Japan that were phylogenetically situated in the same cluster of viruses related to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

18 Nov 2022

Researchers identify a conserved site on SARS-CoV-2 spike that a broadly neutralizing macrocyclic peptide can target

Researchers explored the efficiency of a macrocyclic peptide in inhibiting the SARS-CoV-2 spike protein.

17 Nov 2022

The viral fitness and antigenic relationship among Omicron sublineages

Researchers used mouse models and human airway cell cultures to investigate the relative viral replication rates and cross-neutralization against SARS-CoV-2 Omicron sublineages.

14 Nov 2022

What is the role of adenoviruses in human health?

With advances in molecular biology informing recent developments in vaccinology, gene therapy, and other fields of medicine, human adenoviruses (HAdVs) have been of primary importance in medical research. A recent review looks at the promises of HAdVs, their potential dangers, and future challenges.

9 Nov 2022

Beckman Coulter Life Sciences and Pillar Biosciences Sign Application Development Agreement for the Biomek NGeniuS System

More companies around the world continue turning to Beckman Coulter Life Sciences, a global leader in laboratory automation and innovation, for their next generation sequencing (NGS) needs with the Biomek NGeniuS System.

From Beckman Coulter Life Sciences 4 Nov 2022

The importance of accurate pipetting in biomedical laboratory work

In this interview, Stephanie Stursberg, Group Product Manager for pipetting platforms at INTEGRA Biosciences, talks to NewsMedical about the importance of accurate and efficient pipetting in biomedical laboratory work.

From INTEGRA Biosciences 2 Nov 2022

Researchers study the unique adaptability of small intestinal bacteria for the first time

Bacteria in the small intestine adapt dynamically to our nutritional state, with individual species disappearing and reappearing.

1 Nov 2022

Vaccination- and/or natural infection-induced immune responses against SARS-CoV-2 Omicron subvariants

Researchers comparatively evaluated the neutralization antibody titers for SARS-CoV-2 Omicron VOC subvariants BA.1, BA.2, BA.4/5 among individuals with ancestral B.1 strain infections, vaccinated individuals, or with hybrid immunity from breakthrough infections and vaccinations with Delta or Gamma VOCs.

27 Oct 2022

Exploring new therapeutic targets and biomarkers for neurodegenerative disorders

In this interview, Dr. Shebna Massey discusses neurodegenerative diseases such as Alzheimer's, Parkinson's, Huntington's, and more. She also discusses and explores new therapeutic targets and biomarkers for these diseases.

From Sino Biological Inc. 26 Oct 2022

New diagnostic method applies machine learning to advanced genomics data to detect sepsis

Sepsis, the overreaction of the immune system in response to an infection, causes an estimated 20% of deaths globally and as many as 20 to 50% of U.S. hospital deaths each year.

24 Oct 2022

Combining host gene expression profiling and metagenomic pathogen detection from plasma nucleic acid enables accurate sepsis diagnosis

Researchers developed integrated host-microbe plasma metagenomics to facilitate sepsis diagnosis.

24 Oct 2022

Beckman Coulter Life Sciences presenting at ASHG

Beckman Coulter Life Sciences, a global leader in laboratory automation and innovation, will have a full team of dedicated professionals and informative programming at the American Society of Human Genetics (ASHG) Annual Meeting October 25-29, 2022 in Los Angeles, California at the Los Angeles Convention Center.

From Beckman Coulter Life Sciences 20 Oct 2022

Rapid and robust pipeline for developing mRNA vaccines for future SARS-CoV-2 variants

A recent study under review at the journal Scientific Reports and currently available on the Research Square* preprint server reported the development of a robust pipeline for fabricating an mRNA vaccine portfolio to combat current and future coronavirus outbreaks, other infectious diseases, and cancer.

19 Oct 2022

Researchers examine how fermented vegetables affect inflammation markers in women

Western females can consume 0.5 g of fermented vegetables each day for six weeks without experiencing any major side effects

16 Oct 2022

Motif-based SARS-CoV-2 protein-human protein interactions as potential antiviral target sites

Researchers performed a ProP-PD (proteomic peptide phage display) analysis to identify peptides from intrinsically disordered human (host) proteome regions that bind with SARS-CoV-2 genome-encoded folded protein domains (PDs).

13 Oct 2022

Precise DNA cleavage using new CRISPR-Cas approach

A team led by investigators at Massachusetts General Hospital (MGH) has overcome a major constraint for cutting and editing DNA by CRISPR-Cas enzymes and other technologies.

11 Oct 2022

Independent Task Force report outlines a One Health approach to address risk factors for future pandemics

The Independent Task Force on COVID-19 and other Pandemics (www.independentcovidtaskforce.org) announced that their report "Pandemic Origins and a One Health Approach to Preparedness and Prevention: Solutions Based on SARS-CoV-2 and Other RNA Viruses" has been published in the Proceedings of the National Academy of Sciences.

10 Oct 2022

Light-Seq technology for barcoding and deep-sequencing selected cell populations in tissues

Under the microscope, researchers often observe different cell types organizing themselves in peculiar patterns within tissues, or sometimes a rare cell type that stands out by occupying a unique position, exhibiting an unusual shape, or expressing a specific biomarker molecule.