Polymerase Chain Reaction News and Research

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Polymerase chain reaction (PCR) is a revolutionary laboratory technique that enables the replication of a specific DNA sequence. Using PCR, millions of copies of a target DNA can be easily synthesized within a short period of time.

Novel hMPV strains linked to rising respiratory infections in young children

Researchers in India discovered novel hMPV lineages A2.2.1 and A2.2.2, emphasizing their role in pediatric respiratory infections and potential public health implications.

6 Jan 2025

Mild avian flu cases in US spark safety warnings for poultry and dairy sectors

Researchers identify 46 mild cases of avian influenza A(H5N1) in U.S. poultry and dairy workers, highlighting low PPE adherence and potential outbreak risks.

2 Jan 2025

CDC study highlights growing tularemia threat in central U.S.

Tularemia cases in the U.S. rose by 56% from 2011 to 2022, with central states and American Indian communities most affected, highlighting diagnostic advancements and health disparities.

2 Jan 2025

Scientists pinpoint regions and species fueling coronavirus evolution in bats

Study uncovers the evolution, transmission, and geographic spread of bat coronaviruses in China, revealing key insights into hotspots and the origins of SARS-CoV-2.

1 Jan 2025

New method detects human fecal contamination in water

The presence of human waste in sewage overflow or stormwater runoffs that ultimately find their way into rivers and lakes is a major public health hazard.

23 Dec 2024

Gut microbiome during acute infection predicts risk of long COVID

The study identifies gut microbiome signatures during acute SARS-CoV-2 infection as predictors of long COVID, enhancing understanding of symptom variability.

16 Dec 2024

Study reveals evidence of 22 viruses in human semen post-infection

This study uncovers the persistence of 22 viruses in human semen, emphasizing the need for updated public health strategies and insights into fertility impacts.

16 Dec 2024

Lipid imbalances hold the key to chronic inflammation in colon cancer

Scientists uncover how disrupted lipid metabolism fuels chronic inflammation in colorectal cancer, offering insights into new therapeutic strategies targeting pro-inflammatory and pro-resolving lipid imbalances.

12 Dec 2024

Virus causes 20 million infections annually as study uncovers hidden drivers of its evolution

Researchers describe the evolutionary origins of hepatitis E virus in rodents.

12 Dec 2024

Gene therapy to prevent stillbirth and premature delivery developed

Researchers investigate the effectiveness of placental nano-based insulin-like 1 growth factor gene therapy to correct fetal growth restriction.

12 Dec 2024

Post-COVID health risks: Obesity fuels sequelae, smoking hits memory

Obesity significantly increases the risk of post-COVID-19 long-term sequelae, while smoking is primarily linked to memory disorders but does not raise the risk of long COVID symptoms or hospitalization.

9 Dec 2024

SARS-CoV-2 spike protein found lingering in brain regions

Researchers find that SARS-CoV-2 spike protein persists in the skull-meninges-brain axis, driving neuroinflammation, neurodegeneration, and heightened vulnerability to brain injuries.

3 Dec 2024

IL-15 improves the effectiveness of GPC3 CAR T cells in targeting solid tumors

The study reveals IL-15's role in enhancing GPC3 CAR T cell therapy, improving tumor targeting and T cell survival in patients with solid cancers.

2 Dec 2024

Reinstating masking curbs hospital viral outbreaks, study confirms

Researchers investigate how changes in hospital policies for SARS-CoV-2 testing and masking have influenced hospital-acquired respiratory viral infections.

1 Dec 2024

Late-liver-stage malaria vaccine delivers 89% protection and boosts cellular immunity

Genetically attenuated malaria parasites with extended liver-stage arrest (GA2) showed 89% protection in a clinical trial, surpassing earlier vaccine candidates and highlighting the potential of cellular immunity.

26 Nov 2024

Microbial density in our gut shapes how diseases are linked to gut health

The study in Cell highlights microbial load's role in gut microbiome variation, suggesting it as a confounder in disease research and a key health determinant.

15 Nov 2024

New biosensor technology could revolutionize mpox diagnosis

A new variant of human mpox has claimed the lives of approximately 5% of people with reported infections in the Democratic Republic of the Congo since 2023, many of them children. Since then, it has spread to several other countries.

14 Nov 2024

New study links circadian gene variants to winter depression

Variants of the PER3 gene disrupt adrenal adaptation to winter light, leading to serotonin disruption and depression-like behaviors in humanized mice models.

13 Nov 2024

Vitamin D receptor activation slows cell overgrowth in pulmonary hypertension

The study demonstrates that activating the vitamin D receptor (VDR) with calcitriol suppresses cell proliferation in pulmonary arterial smooth muscle cells, potentially reducing disease severity in pulmonary arterial hypertension (PAH).

12 Nov 2024

Limited impact of prenatal COVID-19 exposure on child neurodevelopmental outcomes

Research shows prenatal exposure to SARS-CoV-2 linked to slight regulatory behavior improvements in infants, but no significant neurodevelopmental impacts.

12 Nov 2024