Sarcoma News and Research

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Effect of mutations in cancer-driving genes across human cancers

Effect of mutations in cancer-driving genes across human cancers.

9 Aug 2023

Innovative 3D cell culture platform could replace the use of animals in research

PeptiMatrix is the latest spin-out company from the University of Nottingham, providing access to an innovative 3D cell culture platform that aims to replace the use of animals in research.

3 Aug 2023

Fully electrical proof-of-concept biosensor for detecting RNA cancer biomarker sequences in solution at the single-molecule level

A group of researchers investigated single-molecule electrical detection of ribonucleic acid (RNA) cancer biomarkers.

3 Aug 2023

UArizona researcher awarded $1.3 million to study lifestyle interventions in American Indian cancer patients

A University of Arizona Cancer Center researcher was awarded a $1.3 million grant from the National Cancer Institute to study the effectiveness of lifestyle interventions in American Indian patients with obesity-related solid tumor cancers who are preparing for surgery.

20 Jul 2023

Six new Damon Runyon Clinical Investigators announced for 2023

The Damon Runyon Cancer Research Foundation has named six new Damon Runyon Clinical Investigators.

20 Jul 2023

Routine next-generation sequencing can identify BRAF mutations in synovial sarcoma

A new case report was published in Oncotarget's Volume 14 on July 7, 2023, entitled, "Intrathoracic synovial sarcoma with BRAF V600E mutation."

18 Jul 2023

Study sheds light on how viruses override host cell's DNA replication machinery

University of Pittsburgh researchers have shown for the first time how Merkel cell polyomavirus (MCV), which causes an aggressive skin cancer called Merkel cell carcinoma, initiates DNA replication in host cells.

17 Jul 2023

Phase I clinical study of TCR NK cell therapy for sarcoma expected to commence later this year

The University of Texas MD Anderson Cancer Center and Replay today announced that the Food & Drug Administration (FDA) has issued a 'safe to proceed' for the Investigational New Drug (IND) application for NY-ESO-1 TCR/IL-15 NK, an engineered T cell receptor natural killer (TCR NK) cell therapy for advanced synovial sarcoma and myxoid/round cell liposarcoma.

20 Jun 2023

Study of immunotherapy for brain cancer metastases shows promising results

In a phase 2 clinical trial of the immune checkpoint inhibitor pembrolizumab, investigators found that 42 percent of patients with metastatic brain cancer benefited from the therapy, with seven patients in the trial surviving longer than two years.

2 Jun 2023

2023 PCRF grant recipients announced for exploring new, safer treatments for pediatric cancers

The Pediatric Cancer Research Foundation, a nonproﬁt focused on transforming pediatric cancer care by accelerating research breakthroughs, today announced the 19 recipients of its 2023 research grants.

26 May 2023

Scientists unveil a metabolic Achilles' heel in pancreatic cancer

Research unveils the significance of uridine as a metabolic fuel in pancreatic ductal adenocarcinoma (PDA) cells under glucose-deprived conditions. Uridine utilization, mediated by uridine phosphorylase 1 (UPP1), supports redox balance, survival, and proliferation in PDA, highlighting its potential as a novel therapeutic target in the treatment of this resistant cancer.

23 May 2023

Leveraging cell self-destruction to treat glioblastoma tumors

Glioblastoma is the most common type of brain tumor in adults. The disease is 100% fatal and there are no cures, making it the most aggressive type of cancer. Such a poor prognosis has motivated researchers and neurosurgeons to understand the biology of tumors with the goal of creating better therapies.

7 Apr 2023

$1 million NIH grant to support UTEP's transformative pancreatic cancer research

The University of Texas at El Paso will undertake potentially transformative research on how specific risk factors promote pancreatic cancer development with support from a $1 million grant from the National Institutes of Health's National Cancer Institute.

6 Apr 2023

Novel combination treatment for head and neck cancers leads to antitumor effects

Human papillomavirus (HPV)-negative head and neck squamous cell carcinoma (HNSCC) and lung cancer can have disruptive mutations in TP53and/or CDKN2A tumor suppressor genes, which are associated with poor patient survival.

5 Apr 2023

What is currently known about the mechanisms by which DNA tumor viruses evade uracil-mediated antiviral immunity?

Researchers reviewed the existing knowledge on the mechanisms through which DNA tumor viruses evade the antiviral immunity mediated through mis-incorporated uracil (U).

3 Apr 2023

Pathologic complete response can be used as a prognostic factor for clinical outcomes in soft tissue sarcoma patients

Combined long-term survival results from nonrandomized phase II trial NRG Oncology RTOG 0630 and the ancillary analysis of the combined NRG-RTOG 0630/9514 trials indicate that pathologic complete response (pCR) is associated with improved survival outcomes for patients with localized soft tissue sarcoma (STS) who receive preoperative chemoradiotherapy or radiotherapy.

31 Mar 2023

Sarcoma News and Research

Effect of mutations in cancer-driving genes across human cancers

Innovative 3D cell culture platform could replace the use of animals in research

Fully electrical proof-of-concept biosensor for detecting RNA cancer biomarker sequences in solution at the single-molecule level

UArizona researcher awarded $1.3 million to study lifestyle interventions in American Indian cancer patients

Six new Damon Runyon Clinical Investigators announced for 2023

Routine next-generation sequencing can identify BRAF mutations in synovial sarcoma

Study sheds light on how viruses override host cell's DNA replication machinery

Phase I clinical study of TCR NK cell therapy for sarcoma expected to commence later this year

Study of immunotherapy for brain cancer metastases shows promising results

2023 PCRF grant recipients announced for exploring new, safer treatments for pediatric cancers

Scientists unveil a metabolic Achilles' heel in pancreatic cancer

Leveraging cell self-destruction to treat glioblastoma tumors

$1 million NIH grant to support UTEP's transformative pancreatic cancer research

Novel combination treatment for head and neck cancers leads to antitumor effects

What is currently known about the mechanisms by which DNA tumor viruses evade uracil-mediated antiviral immunity?

Pathologic complete response can be used as a prognostic factor for clinical outcomes in soft tissue sarcoma patients

Using unsupervised machine learning algorithms to classify osteosarcoma

When mass spectrometry redefines molecular biology and biochemistry – the future of spatial omics

Nirogacestat shows promising results in patients with desmoid tumors

Cancer-causing viruses use a human protein to evade the innate immune response

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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