Bone Marrow News and Research

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Bone Marrow is the soft, sponge-like tissue in the center of most bones. It produces white blood cells, red blood cells, and platelets.

Study explores augmented ACL reconstruction procedure

An innovative procedure that explores the use of amnion, bone marrow concentrate and suture tape in anterior cruciate ligament reconstruction may result in earlier return to play protocols for athletes, suggests a new Marshall University study published in the May 6, 2019, edition of Arthroscopy Techniques, a companion to Arthroscopy: The Journal of Arthroscopic and Related Surgery.

4 Jun 2019

Blood stem cell breakthrough could spare some patients from side effects of cancer treatments

A method of growing blood stem cells in the laboratory has been developed by researchers at Stanford University and the University of Tokyo, in a breakthrough that could spare some people with blood and immune disorders from the side effects of intensive chemotherapy and radiotherapy.

31 May 2019

IU researchers, collaborators receive grant to develop immunotherapy treatments for cancer

A team of researchers from Indiana University and Memorial Sloan Kettering Cancer Center have been awarded a $4.1 million National Cancer Institute "Cancer Moonshot" grant to develop immunotherapy treatments for cancer in children and adolescents, especially those with leukemia.

31 May 2019

Combination treatment effective as front-line therapy for select chronic lymphocytic leukemia patients

Ibrutinib and venetoclax, two FDA-approved drugs for treating chronic lymphocytic leukemia, have been shown to be effective when given together for high-risk and older patients with the disease, according to a study at The University of Texas MD Anderson Cancer Center.

30 May 2019

Scientists use gold nanoparticles to edit genes tied to HIV, inherited blood disorders

Scientists at Fred Hutchinson Cancer Research Center took a step toward making gene therapy more practical by simplifying the way gene-editing instructions are delivered to cells.

28 May 2019

Overexpression of tumor suppressor gene may lead to B-cell lymphoma, study finds

Miguel Gallardo, researcher and coordinator of the H12O-CNIO Haematological Malignancies Clinical Research Unit headed by Joaquín Martínez at the Spanish National Cancer Research Centre, has participated in a study that revealed that hnRNP K overexpression may cause B-cell lymphomas, the most common types of blood cancer.

24 May 2019

Researchers map bone-marrow microenvironment to shed new light on leukemia

Stem cells are surrounded and protected by the stem-cell niche - the microenvironment - of the tissue in which they are found.

24 May 2019

Zebrafish may help researchers to use blood stem cells instead of bone marrow transplants

Blood diseases such as leukemia and lymphoma are currently treated with bone marrow transplants -- a transfer of blood stem cells from a healthy person to a patient in need.

21 May 2019

First Footage of T-Cells Training To Fight Pathogens Revealed

Immunologists at The University of Texas at Austin have recorded visuals of T-cells learning what kind of cells to ignore when fighting pathogens, to ensure they do not attack healthy cells and tissues when fighting disease. It is the first time that this process has been captured on video.

20 May 2019

New tool provides standards for describing characteristics and use of cell therapies

Cell therapies including so-called "stem cells" are increasingly being marketed and used for the treatment of musculoskeletal disorders - despite questions about these treatments and their effectiveness.

18 May 2019

Probiotic-derived molecule optimizes the immune system to combat viral inflammatory diseases

The existence of certain microorganisms in your gut may bolster the immune system's ability to fend off a herpes viral attack that can cause fatal brain inflammation, reports a new City of Hope-led study.

14 May 2019

WVU researcher studies stubborn blood disease that strikes children

Treating a stubborn blood disease that strikes children may come down to tweaking energy production in stem cells, suggests research out of West Virginia University.

14 May 2019

Slow-release HIV vaccine shows promise in preclinical trials

A new slow-release vaccine has been shown to boost the immune system’s response to the HIV virus. The vaccine is given in small doses over a period of days, compared to one large dose.

10 May 2019

Researchers design promising cell-based regenerative therapy approach for periodontitis

Researchers have designed a safer, faster and cheaper cell-based regenerative therapy approach for the treatment of one of the most common human dental diseases, namely periodontitis.

10 May 2019

Routine screening for SCD among refugees could help prevent life-threatening complications

Hematologists are zeroing in on the escalating humanitarian crisis in southern Europe by assessing the burden of blood disorders among refugees and identifying strategies to facilitate more timely identification and treatment of refugees with sickle cell disease.

9 May 2019

Human iPSCs make more tiny 'cargo packets' to deliver cellular aging therapies

Johns Hopkins scientists report that adult cells reprogrammed to become primitive stem cells, called induced pluripotent stem cells, make tiny "cargo packets" able to deliver potentially restorative or repairing proteins, antibodies or other therapies to aged cells.

From Johns Hopkins Medicine 8 May 2019

Biomarker may help predict first treatment option for metastatic colorectal cancer patients

Foundational research by a City of Hope physician-scientist and his colleagues could one day help metastatic colorectal cancer patients decide whether to choose immunotherapy or chemotherapy as their first treatment option.

2 May 2019

Researchers define role of rare, influential cells in the bone marrow

Researchers have defined the roles of various cells in the bone marrow that are thought to control the fate of the nearly half million blood cells that develop there each day.

23 Apr 2019

UAB receives $17 million grant to explore immune cells in inaccessible tissues of the human body

University of Alabama at Birmingham researchers will receive $17.8 million in federal funding to attack a key "knowledge gap" in human immunology -- how the B cells and antibody-secreting cells that reside in tissues and organs differ from those found in blood.