Fibrosis News and Research

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Fibrosis is the growth of fibrous tissue.

3D bioengineered model could reveal new treatments for deadly lung disease

A 3D bioengineered model of lung tissue built by University of Michigan researchers is poking holes in decades worth of flat, Petri dish observations into how the deadly disease pulmonary fibrosis progresses.

14 Sep 2020

Keto diet could be beneficial for elderly COVID-19 patients

A recent study by researchers at Yale School of Medicine, New York University Langone Health and Washington University School of Medicine, claims that the ketogenic diet (high fat, low carbohydrate diet) is capable of mitigating clinical outcomes of coronavirus disease 2019 (COVID-19) in elderly people by improving immune-metabolic functions and reducing inflammation. The study is currently available on the bioRxiv* preprint server.

14 Sep 2020

Sticky DNA webs may cause tissue damage associated with severe COVID-19 infections

Sticky webs of DNA released from immune cells known as neutrophils may cause much of the tissue damage associated with severe COVID-19 infections, according to two new studies published September 14 in the Journal of Experimental Medicine.

14 Sep 2020

Yale researchers identify possible treatment for Duchenne muscular dystrophy

Researchers at Yale have identified a possible treatment for Duchenne muscular dystrophy (DMD), a rare genetic disease for which there is currently no cure or treatment, by targeting an enzyme that had been considered "undruggable."

12 Sep 2020

Novel discovery could lead to stem cell-based treatment for heart failure

Blocking an enzyme linked with inflammation makes it possible for stem cells to repair damaged heart tissue, new research from UC Davis Health scientists shows.

10 Sep 2020

A novel gene involved in primary lymphedema identified

The Human Molecular Genetics laboratory of the de Duve Institute (UCLouvain), headed by Professor Miikka Vikkula, recently identified mutations in a novel gene, ANGPT2, responsible for primary lymphedema.

10 Sep 2020

Vapers, smokers, and non-smokers with chronic conditions have higher risks for COVID-19

What do vapers, smokers, and non-smokers with chronic conditions such as high blood pressure or diabetes have in common? They all are at higher risk for COVID-19.

10 Sep 2020

Study reveals how B cells react to SARS-CoV-2

In an exciting immunological medRxiv preprint paper, researchers from Germany and Russia analyzed adaptive immune response in severely affected patients with coronavirus disease (COVID-19). They demonstrated a protracted immune reaction characterized by egress of B lymphocytes into the blood.

9 Sep 2020

Scientists discover tissue reparative role for a rare immune cell type in the gut

Scientists from King's College London have discovered an unexpected tissue reparative role for a rare immune cell type in the gut that could tip toward fibrosis or cancer if dysregulated.

8 Sep 2020

Researchers create new and quicker method of diagnosing diseases

A new and quicker method of diagnosing diseases in patients has been created by researchers at the University of Leeds.

2 Sep 2020

Pharmaceutical researchers aim to create better CBD-like treatments

Cannabidiol (CBD) is an increasingly popular wellness trend. The compound, which occurs naturally in cannabis plants, is added to many products that claim to reduce anxiety, alleviate pain and more, without the intoxication of its cousin tetrahydrocannabinol (THC).

2 Sep 2020

Majority of U.S. COVID-19 fatalities had underlying medical conditions

Early on in the coronavirus disease (COVID-19) pandemic, there was little data on the virus and how it affects the body. As the virus spread across the globe, data showed that some people were at a higher risk of developing severe disease and dying from the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

31 Aug 2020

Researchers identify roles of matrix stiffness and mechanotransduction in cardiac reprogramming

Cardiovascular disease is the leading cause of death in humans. Worldwide, as the population ages, the burden of treating heart failure is increasing; opportunities for heart transplantation cannot keep pace.

31 Aug 2020

New discovery could help protect the liver from fructose-induced diseases

A team of international researchers including Monash University academics has discovered that, contrary to previous belief, fructose causes liver toxicity by changing the barrier function of the intestine.

27 Aug 2020

Researchers identify how promising therapy may work to improve adverse effects of NAFLD

A team led by researchers at Massachusetts General Hospital (MGH) has taken an important step forward in the goal of developing a potential treatment for non-alcoholic fatty liver disease (NAFLD), the most common form of chronic liver disease.

26 Aug 2020

Inflammatory protein produced by mast cells contributes to fibrosis in gastric cancer

Gastric cancer, one of the leading causes of cancer-associated mortality worldwide, is renowned for its ability to disseminate throughout the peritoneal cavity.

26 Aug 2020

Estradiol appears to help in female SARS-CoV-2 infection

A new study published on the preprint server medRxiv in August 2020 shows that the risk of infection is high for pre-menopausal women but the risk of death is much higher for men in the same age group and throws light on the protective nature of estradiol therapy in post-menopausal women.

26 Aug 2020

Antihypertensives improve COVID-19 survival rates

Previous studies have also linked hypertension to severe coronavirus disease (COVID-19). Now, a new study by researchers at the University of East Anglia's Norwich Medical School has found that the risk of severe COVID-19 and death was reduced for patients with high blood pressure who were taking Angiotensin-Converting Enzyme inhibitors (ACEi) or Angiotensin Receptor Blockers (ARB).

24 Aug 2020

Ciliary proteins play vital role in cardiovascular functions and genetic diseases

Research from Chapman University provides new insight into the characteristics of crucial proteins within the ciliary membrane that play vital roles in human genetic diseases and cardiovascular functions.

20 Aug 2020

Children play a larger role in the community spread of COVID-19 than previously thought

In the most comprehensive study of COVID-19 pediatric patients to date, Massachusetts General Hospital (MGH) and Mass General Hospital for Children (MGHfC) researchers provide critical data showing that children play a larger role in the community spread of COVID-19 than previously thought

20 Aug 2020

Fibrosis News and Research

Further Reading

3D bioengineered model could reveal new treatments for deadly lung disease

Keto diet could be beneficial for elderly COVID-19 patients

Sticky DNA webs may cause tissue damage associated with severe COVID-19 infections

Yale researchers identify possible treatment for Duchenne muscular dystrophy

Novel discovery could lead to stem cell-based treatment for heart failure

A novel gene involved in primary lymphedema identified

Vapers, smokers, and non-smokers with chronic conditions have higher risks for COVID-19

Study reveals how B cells react to SARS-CoV-2

Scientists discover tissue reparative role for a rare immune cell type in the gut

Researchers create new and quicker method of diagnosing diseases

Pharmaceutical researchers aim to create better CBD-like treatments

Majority of U.S. COVID-19 fatalities had underlying medical conditions

Researchers identify roles of matrix stiffness and mechanotransduction in cardiac reprogramming

New discovery could help protect the liver from fructose-induced diseases

Researchers identify how promising therapy may work to improve adverse effects of NAFLD

Inflammatory protein produced by mast cells contributes to fibrosis in gastric cancer

Estradiol appears to help in female SARS-CoV-2 infection

Antihypertensives improve COVID-19 survival rates

Ciliary proteins play vital role in cardiovascular functions and genetic diseases

Children play a larger role in the community spread of COVID-19 than previously thought

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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