Medical School News and Research

RSS

Duke-NUS scientist awarded major funding to develop therapeutics for chronic inflammation

Associate Professor Lena Ho from Duke-NUS Medical School has been awarded US$1.85 million (approx. S$2.51 million) to further her team's research in developing microproteins into therapeutic targets to treat chronic inflammation.

29 Jul 2024

Advancing hepatic cell carcinoma treatment through mitochondrial DNA targeting

Hepatic cell carcinoma (HCC), the fifth most prevalent malignancy worldwide and the fourth leading cause of cancer-related mortality, poses significant therapeutic challenges.

29 Jul 2024

Understanding iron overload in β-thalassemia: Mechanisms, diagnosis, and treatments

β-Thalassemia is a genetic disorder characterized by reduced or absent synthesis of the beta chains of hemoglobin, leading to ineffective erythropoiesis and severe anemia.

29 Jul 2024

New study highlights paternal influence on child's T1D risk

New research to be presented at this year's Annual Meeting of the European Association for the Study of Diabetes (EASD) (Madrid, 9-13 September) shows that a child is almost twice as likely to develop type 1 diabetes (T1D) if their father has the condition than if their mother has the condition.

27 Jul 2024

Physician posture impacts patient experience and outcomes

A new study suggests that getting at a patient's eye level when talking with them about their diagnosis or care can really make a difference. Sitting or crouching at a hospitalized patient's bedside was associated with more trust, satisfaction and even better clinical outcomes than standing, according to the new review of evidence.

26 Jul 2024

Understanding the epigenetic regulation of hepatic stellate cells in NAFLD

Non-alcoholic fatty liver disease (NAFLD) has emerged as a leading cause of chronic liver disease worldwide, affecting approximately 38% of the global population from 2016 to 2019.

25 Jul 2024

KFF Health News' 'What the Health?': Harris in the spotlight

As Vice President Kamala Harris appears poised to become the Democratic Party’s presidential nominee, health policy in general and reproductive health issues in particular are likely to have a higher profile.

25 Jul 2024

Texas Heart Institute and BiVACOR achieve milestone with total artificial heart implantation

The Texas Heart Institute (THI) and BiVACOR, a clinical-stage medical device company, announced today the successful first-in-human implantation of the BiVACOR Total Artificial Heart (TAH) as part of the U.S. Food and Drug Administration (FDA) Early Feasibility Study (EFS) on July 9, 2024.

25 Jul 2024

Breakthrough gene therapy restores dystrophin protein in Duchenne muscular dystrophy

Indiana University School of Medicine researchers have made a significant breakthrough in developing a new gene therapy approach that restores full-length dystrophin protein, which could lead to new treatments for people with Duchenne muscular dystrophy (DMD).

24 Jul 2024

Personalized text messages effectively promote increased physical activity after cardiovascular events

Exercise is one of the best ways to reduce your risk of heart disease or having a second cardiovascular event, such as a heart attack or stroke.

24 Jul 2024

Comprehensive dataset from A4 study yields key insights about Alzheimer's disease

Data from the Anti-Amyloid Treatment in Asymptomatic Alzheimer's (A4) study, the first and largest clinical trial of pre-symptomatic Alzheimer's disease, is now widely available to researchers studying the condition.

24 Jul 2024

Exploring non-coding RNAs as regulators of notch signaling in breast cancer

Breast cancer (BC) remains one of the most challenging cancers to treat, primarily due to its heterogeneity and propensity for metastasis.

23 Jul 2024

Unraveling the role of TAL1 and miR-146b-5p in T-cell acute lymphoblastic leukemia

T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive form of leukemia that arises from the malignant transformation of T-cell progenitors.

23 Jul 2024

Evaluation and treatment of early Lyme disease

Every year in the United States, an estimated 476,000 people are diagnosed and treated for Lyme disease. The estimate comes from the U.S. Centers for Disease Control and Prevention (CDC).

23 Jul 2024

Long-term high systolic blood pressure linked to increased stroke risk, study finds

High blood pressure is known to increase a person's chances of having a stroke.

23 Jul 2024

PrEPVacc HIV vaccine trial shows no reduction in infections

The results of the PrEPVacc HIV vaccine trial conducted in Eastern and Southern Africa, which ran between 2020 and 2024, show conclusively that neither of the two experimental vaccine regimens tested reduced HIV infections among the study population.

23 Jul 2024

New findings shed light on AI's potential in clinical settings

Researchers at the National Institutes of Health (NIH) found that an artificial intelligence (AI) model solved medical quiz questions - designed to test health professionals' ability to diagnose patients based on clinical images and a brief text summary - with high accuracy.

23 Jul 2024

Higher Brain Care Score associated with lower risk of late-life depression

Late-life depression, typically defined as depression with onset in individuals over 60 years of age, can affect up to a third or more of people older than 60 and can be debilitating.

23 Jul 2024

Study reveals reduced type 1 diabetes risk in post-10-year-old girls

New research presented at this year's Annual Meeting of the European Association for Study of Diabetes (Madrid, Spain, 9-13 September) shows that the risk of developing type 1 diabetes (T1D) decreases markedly in girls after age 10 years, while the risk in boys stays the same.

22 Jul 2024

Combination of sEphB4-HSA and pembrolizumab shows promise in HPV-negative EphrinB2 positive HNSCC

A new research paper was published in Oncotarget's Volume 15 on July 10, 2024, entitled, "Improved efficacy of pembrolizumab combined with soluble EphB4-albumin in HPV-negative EphrinB2 positive head neck squamous cell carcinoma."

22 Jul 2024

Medical School News and Research

Duke-NUS scientist awarded major funding to develop therapeutics for chronic inflammation

Advancing hepatic cell carcinoma treatment through mitochondrial DNA targeting

Understanding iron overload in β-thalassemia: Mechanisms, diagnosis, and treatments

New study highlights paternal influence on child's T1D risk

Physician posture impacts patient experience and outcomes

Understanding the epigenetic regulation of hepatic stellate cells in NAFLD

KFF Health News' 'What the Health?': Harris in the spotlight

Texas Heart Institute and BiVACOR achieve milestone with total artificial heart implantation

Breakthrough gene therapy restores dystrophin protein in Duchenne muscular dystrophy

Personalized text messages effectively promote increased physical activity after cardiovascular events

Comprehensive dataset from A4 study yields key insights about Alzheimer's disease

Exploring non-coding RNAs as regulators of notch signaling in breast cancer

Unraveling the role of TAL1 and miR-146b-5p in T-cell acute lymphoblastic leukemia

Evaluation and treatment of early Lyme disease

Long-term high systolic blood pressure linked to increased stroke risk, study finds

PrEPVacc HIV vaccine trial shows no reduction in infections

New findings shed light on AI's potential in clinical settings

Higher Brain Care Score associated with lower risk of late-life depression

Study reveals reduced type 1 diabetes risk in post-10-year-old girls

Combination of sEphB4-HSA and pembrolizumab shows promise in HPV-negative EphrinB2 positive HNSCC

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News