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Excessive neuropeptide secretion in the lungs can lead to fluid buildup and poor oxygenation

COVID-19 has put a spotlight on the pulmonary and nervous systems, but there is still much to learn about how they interact. Researchers at University of California San Diego School of Medicine recently explored this relationship in the context of a childhood lung disease, but their findings may also apply to COVID-19 symptoms.

17 Mar 2022

Novel metabolic mechanisms contribute to how ovarian cancer evades immune attack, research finds

High-grade serous carcinoma is the most aggressive form of ovarian cancer and accounts for the majority of advanced-stage cases.

16 Mar 2022

Researchers receive grant to find answers to taste loss in COVID patients

Up to 80% of individuals who've had COVID-19 report temporary or lasting changes in their sense of taste, and scientists are working to better understand the biological basis of why, including whether our taste buds are a direct virus target.

15 Mar 2022

Study explores neutralization of SARS-CoV-2 Omicron variant by subunit vaccine boosters

A new study assessed the neutralization induced by subunit vaccine boosters specific for the SARS-CoV-2 Omicron variant of concern.

14 Mar 2022

Engineered SARS-CoV-2 immunogens elicit broadly neutralizing antibodies

New research describes a novel approach whereby SARS-2 antigens were analyzed for conserved sites that may be targeted by broadly neutralizing antibodies that will confer immunity to other Sarbecoviruses.

10 Mar 2022

A promising approach for COVID-19 prophylaxis

SARS-CoV-2 viruses can hide from recognition by the immune system. However, the antiviral immune receptor RIG-I can be stimulated, which improves protection against lethal SARS-CoV-2 infections.

8 Mar 2022

New treatment strategy makes pancreatic tumors sensitive to immunotherapy, mice study shows

Pancreatic cancer is one of the most aggressive and deadly tumor types and notorious for its resistance to virtually all types of treatment, including newer immunotherapies.

7 Mar 2022

Combating COVID cytokine storm with targeted nucleic acid therapies

Researchers examine current nucleic acid-based treatments against COVID-19 and their methods of action.

6 Mar 2022

Novel drug candidate protects lab mice against cognitive decline by reducing brain inflammation

An anti-inflammatory drug candidate, known as 3,6'-dithiopomalidomide (DP), designed by researchers at the National Institute on Aging, protected lab mice against cognitive decline by reducing brain inflammation.

2 Mar 2022

Intestinal cells can change specializations during their lives, finds study

Intestinal cells can change specializations during their lives. The BMP signaling pathway – an important communication mechanism between cells – appears to be the driver of these changes.

1 Mar 2022

Scientists discover an innate form of immunological memory in the intestine

The innate immune system plays a crucial role in regulating host-microbe interactions, and especially in providing protection against pathogens that invade the mucosa.

28 Feb 2022

Researchers demonstrate the powerful gene silencing effects of HDO technology

T and B lymphocytes, which are part of a group of immune cells commonly called white blood cells, work together to eliminate foreign invaders in the body such as viruses.

28 Feb 2022

MUSC study sheds light on better ways to prevent and treat colorectal cancer

An MUSC Hollings Cancer Center study sheds light on better ways to prevent and treat colorectal cancer, which often is found at advanced stages when it's much harder to treat.

28 Feb 2022

Study examines the effect of sevoflurane on sleep disturbance caused by systemic inflammation

Getting a good night's sleep can sometimes be a challenge, but inflammation may make it even more difficult.

24 Feb 2022

Scientists discover how a rare genetic disorder disrupts key neural interactions in the developing brain

Every time you chew, talk, yawn, or sense the zap of a toothache, cranial nerve cells are shuttling electrochemical signals to your brain.

23 Feb 2022

Tiny lipid-based nanoparticles carry genetic instructions directly into the lungs

Researchers at the Tufts University School of Engineering are building a reputation for precision targeting in drug delivery.

23 Feb 2022

Researchers create artificial tendons in vitro from human stem cells

Researchers from Tokyo Medical and Dental develop artificial tendons in vitro from human stem cells that could fix common tendon injuries such as Achilles tendon rupture.

23 Feb 2022

Study provides a potent biparatopic antibody against all SARS-CoV-2 variants of concern

Researchers demonstrated the potent neutralization of SARS-CoV-2 VOCs, including Omicron by the biparatopic human heavy chain variable domain.

22 Feb 2022

Mouse-adapted virus model to study persistent COVID induced lung disease

Researchers develop a mouse model to identify early biomarkers and test countermeasures needed to detect and prevent PASC.

21 Feb 2022

Novel ACE2-blocking antibody protects against all SARS-CoV-2 VOCs

Researchers identify 87G7, a SARS-CoV-2 neutralizing human monoclonal antibody with remarkable broad-spectrum neutralization and protection efficacy.

21 Feb 2022

Mouse Model News and Research

Excessive neuropeptide secretion in the lungs can lead to fluid buildup and poor oxygenation

Novel metabolic mechanisms contribute to how ovarian cancer evades immune attack, research finds

Researchers receive grant to find answers to taste loss in COVID patients

Study explores neutralization of SARS-CoV-2 Omicron variant by subunit vaccine boosters

Engineered SARS-CoV-2 immunogens elicit broadly neutralizing antibodies

A promising approach for COVID-19 prophylaxis

New treatment strategy makes pancreatic tumors sensitive to immunotherapy, mice study shows

Combating COVID cytokine storm with targeted nucleic acid therapies

Novel drug candidate protects lab mice against cognitive decline by reducing brain inflammation

Intestinal cells can change specializations during their lives, finds study

Scientists discover an innate form of immunological memory in the intestine

Researchers demonstrate the powerful gene silencing effects of HDO technology

MUSC study sheds light on better ways to prevent and treat colorectal cancer

Study examines the effect of sevoflurane on sleep disturbance caused by systemic inflammation

Scientists discover how a rare genetic disorder disrupts key neural interactions in the developing brain

Tiny lipid-based nanoparticles carry genetic instructions directly into the lungs

Researchers create artificial tendons in vitro from human stem cells

Study provides a potent biparatopic antibody against all SARS-CoV-2 variants of concern

Mouse-adapted virus model to study persistent COVID induced lung disease

Novel ACE2-blocking antibody protects against all SARS-CoV-2 VOCs

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