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Clathrin protein may have a role in suppressing tumors

Newly published research by Indiana University structural biologist Joel Ybe and colleagues identifies a "topology switch" in the protein clathrin, the function of which may shed light on molecular processes involved in tumor suppression.

16 Jan 2013

Supreme Court agrees to hear case challenging federal anti-prostitution pledge

"The Supreme Court agreed on Friday to consider whether the government can require groups that receive federal funding for overseas HIV/AIDS programs to have explicit policies that oppose prostitution and sex trafficking," Reuters reports.

16 Jan 2013

Abortion, contraception coverage fights continue as Roe v. Wade anniversary nears

Abortion and contraception coverage make news in Texas, Virginia and Pennsylvania while both sides prepare for the 40th anniversary of the Roe v. Wade decision.

16 Jan 2013

NPR's 'Shots' blog examines cholera epidemic in Haiti; U.N. SG calls for continued international support of country

NPR's "Shots" blog examines the cholera epidemic in Haiti and addresses the controversy surrounding the U.N.'s role in the outbreak, noting, "Most scientists now think Nepalese soldiers unwittingly brought cholera to Haiti when they joined a U.N. peacekeeping force there in 2010."

16 Jan 2013

Diospyrin inactivates a drug target for tuberculosis in new way

A compound from the South African toothbrush tree inactivates a drug target for tuberculosis in a previously unseen way.

16 Jan 2013

p53 activation suppresses malic enzyme expression and leads to senescence in pre-cancerous cells

It is perhaps impossible to overstate the importance of the tumor suppressor gene p53. It is the single most frequently mutated gene in human tumors. p53 keeps pre-cancerous cells in check by causing cells, among other things, to become senescent - aging at the cellular level. Loss of p53 causes cells to ignore the cellular signals that would normally make mutant or damaged cells die or stop growing.

16 Jan 2013

TSC22D4 gene plays a key role in the onset of cachexia

Cachexia or wasting is a condition affecting up to 70 percent of cancer patients, depending on the type of cancer. It is characterized by a dramatic loss of body weight that is independent of food intake. Cachexia is seen particularly often and most pronounced in patients suffering from cancers of the digestive tract and the lungs.

16 Jan 2013

Over-expression of NEK2 in cancer cells significantly enhances drug resistance

Increased NEK2 gene expression linked to increased drug resistance, faster cancer growth, and poorer patient outcome - The finding may improved diagnostic and prognostic tools for cancer care and could lead to improved cancer therapies

16 Jan 2013

Researchers discover molecular blueprint behind the IFIT protein

Researchers at McGill University and the Research Center for Molecular Medicine (CeMM) of the Austrian Academy of Sciences have discovered the molecular blueprint behind the IFIT protein.

15 Jan 2013

Study highlights the risk that female teenagers face when they go online

A new study highlights the risk that female teenagers face when they go online - a risk heightened for teen girls who have been victims of abuse or neglect.

15 Jan 2013

Viewpoints: Health law's 'sticker shock;' Changing Medicare eligibility age is not a simple solution

President Obama said a fair bit during the fiscal-cliff negotiations - speaking for 45 minutes in one 50-minute meeting, for example - but today let's zero in on the claim he kept repeating: "We don't have a spending problem. We have a health-care problem." For our money - and yours - those are two of the most remarkable sentences our Orator in Chief has ever strung together.

15 Jan 2013

Novel system could allow broader screening for esophageal cancer, other conditions

Physicians may soon have a new way to screen patients for Barrett's esophagus, a precancerous condition usually caused by chronic exposure to stomach acid. Researchers at the Wellman Center for Photomedicine at Massachusetts General Hospital (MGH) have developed an imaging system enclosed in a capsule about the size of a multivitamin pill that creates detailed, microscopic images of the esophageal wall. The system has several advantages over traditional endoscopy.

15 Jan 2013

Children with chronic medical conditions more likely to use alternative medicine

Children who regularly see specialists for chronic medical conditions are also using complementary medicine at a high rate, demonstrates recently published research from the University of Alberta and the University of Ottawa.

15 Jan 2013

Obese youngsters at far greater risk than had been supposed

While a great deal of research on childhood obesity has spotlighted the long-term health problems that emerge in adulthood, a new UCLA study focuses on the condition's immediate consequences and shows that obese youngsters are at far greater risk than had been supposed.

15 Jan 2013

Waxman urges Biden to consider mental health in gun violence talks; Mentally ill missing from background check system

As the nation grapples with mental health issues in the wake of recent violence, issues related to restricting gun ownership for the mentally ill take shape on Capitol Hill.

15 Jan 2013

Aggressive breast cancer’s metastasis molecular switch identified

Scientists at Weill Cornell Medical College have discovered the molecular switch that allows aggressive triple negative breast cancer cells to grow the amoeba-like protrusions they need to crawl away from a primary tumor and metastasize throughout the body. Their findings, published in Cancer Cell, suggest a novel approach for developing agents to treat cancer once it has spread.

15 Jan 2013

Research News and Research

Clathrin protein may have a role in suppressing tumors

Supreme Court agrees to hear case challenging federal anti-prostitution pledge

Abortion, contraception coverage fights continue as Roe v. Wade anniversary nears

NPR's 'Shots' blog examines cholera epidemic in Haiti; U.N. SG calls for continued international support of country

Diospyrin inactivates a drug target for tuberculosis in new way

p53 activation suppresses malic enzyme expression and leads to senescence in pre-cancerous cells

TSC22D4 gene plays a key role in the onset of cachexia

Over-expression of NEK2 in cancer cells significantly enhances drug resistance

Researchers discover molecular blueprint behind the IFIT protein

Study highlights the risk that female teenagers face when they go online

Viewpoints: Health law's 'sticker shock;' Changing Medicare eligibility age is not a simple solution

Novel system could allow broader screening for esophageal cancer, other conditions

Children with chronic medical conditions more likely to use alternative medicine

Obese youngsters at far greater risk than had been supposed

Waxman urges Biden to consider mental health in gun violence talks; Mentally ill missing from background check system

Aggressive breast cancer’s metastasis molecular switch identified

Spirituality associated with poor mental health

New hope for people with sound-induced deafness

Pediatric CKD rates increase substantially in south of England

Arterial versus venous graft debate continues

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