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Rapid finger stick test to detect antibodies against SARS-CoV-2 variants

A new preprint reports a semi-quantitative test that can measure neutralizing antibodies to the SARS-CoV-2 pathogen at the point of care, using a finger stick or venipuncture blood.

16 Nov 2021

Deficient spike-specific T cell responses and inability to neutralize SARS-CoV-2 variants 12 month post-infection

Researchers conducted a comprehensive, longitudinal, long-term immune study, including functional assays to assess immune fitness against antigenically different VoC. The study is currently available on the preprint server medRxiv* while awaiting peer review.

15 Nov 2021

Researchers develop a highly efficient method to generate immune cells for cancer therapies

A Ludwig Cancer Research study has devised a highly efficient method to generate large numbers of immune cells specifically engineered to recognize neoantigens - small fragments of randomly mutated proteins that are typically unique to a patient's cancer - and destroy the tumors that express them.

15 Nov 2021

Immune response elicited by SARS-CoV-2 vaccines in infliximab and vedolizumab-treated patients with IBD

A recent study evaluates the immune responses elicited by COVID-19 vaccines in infliximab- or vedolizumab-treated IBD patients.

15 Nov 2021

Histone mimicry as a mechanism through which SARS-CoV-2 disrupts host cell epigenetic regulation

A recent study investigates histone mimicry as a mechanism by SARS-CoV-2 for disrupting epigenetic regulation to evade host cell responses to infection.

15 Nov 2021

Study identifies a host factor that reflects different levels of inflammation within mild COVID-19 cases

A new study investigates serum from COVID-19 convalescents and uninfected individuals to determine the molecular mechanisms of host responses.

15 Nov 2021

Machine learning analysis of long non-coding RNAs reveals new prognostic cancer biomarkers

A new batch of prognostic cancer biomarkers have been discovered in an area where few have gone looking before. Researchers have unveiled a catalogue of 166 prognostic biomarkers, generated by analyzing long non-coding RNAs (lncRNAs) – which are understudied in cancer research.

15 Nov 2021

Stem cell treatment reduced deaths related to cardiovascular issues, not hospitalization

Stem cell therapy helped to reduce the number of heart attacks, strokes and death among people with chronic, high-risk, NYHA class II or III heart failure with reduced ejection fraction (HFrEF), especially among those who have higher levels of inflammation, yet hospitalization was not reduced, according to late-breaking research presented today at the American Heart Association's Scientific Sessions 2021.

15 Nov 2021

Inflammatory chemicals involved in fat metabolism play key role in ALS, study shows

A new study using genetically engineered mice and human cell and tissue samples has added to evidence that higher levels of inflammatory chemicals involved in fat metabolism occur in people with amyotrophic lateral sclerosis (ALS), the neuromuscular disorder, also known as Lou Gehrig's disease.

15 Nov 2021

Lamin C important for keeping cell’s genetic material organized, research shows

In a study with lab-grown mouse cells, Johns Hopkins Medicine researchers say they have found that a protein that helps form a structural network under the surface of the cell's "command center" — its nucleus — is key to ensuring that DNA inside it remains orderly.

15 Nov 2021

Researchers discover new gene critical for daily behavioral rhythms

Life is organized on a 24-hour schedule. Central to this regular rhythm is the circadian clock, timekeepers that are present in virtually every organ, tissue and cell type. When a clock goes awry, sleep disruption or a variety of diseases can result.

15 Nov 2021

Anti-platelet drug class fails to extend survival in moderately ill COVID-19 patients

A drug class that blocks the activity of blood platelets and prevents clotting—P2Y12 inhibitors—failed to extend survival or lessen disease severity in patients with COVID-19 who were hospitalized but had a relatively moderate case, a new study finds.

15 Nov 2021

B Cell News and Research

Rapid finger stick test to detect antibodies against SARS-CoV-2 variants

Deficient spike-specific T cell responses and inability to neutralize SARS-CoV-2 variants 12 month post-infection

Researchers develop a highly efficient method to generate immune cells for cancer therapies

Immune response elicited by SARS-CoV-2 vaccines in infliximab and vedolizumab-treated patients with IBD

Histone mimicry as a mechanism through which SARS-CoV-2 disrupts host cell epigenetic regulation

Study identifies a host factor that reflects different levels of inflammation within mild COVID-19 cases

Machine learning analysis of long non-coding RNAs reveals new prognostic cancer biomarkers

Stem cell treatment reduced deaths related to cardiovascular issues, not hospitalization

Inflammatory chemicals involved in fat metabolism play key role in ALS, study shows

Lamin C important for keeping cell’s genetic material organized, research shows

Researchers discover new gene critical for daily behavioral rhythms

Anti-platelet drug class fails to extend survival in moderately ill COVID-19 patients

Research expands the general understanding of transcription process in bacteria

New therapy targets rodents' cells rather than bacterial cells in treating pneumonia

Could drugs derived from microalgae be effective against COVID-19?

SARS-CoV-2 infection inhibited by CCR2 signaling

Smiths Detection: Innovative technology in biothreat detection

Vaccination protects against COVID-19 related hospitalization in patients with and without comorbidity

Mycobacterium tuberculosis may induce resistance to secondary SARS-CoV-2 infection

Can COVID-19 vaccination lead to neurological complications?

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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