Infectious Diseases News and Research

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Study on first new potential drug for tuberculosis in 40 years

454 Life Sciences, a majority-owned subsidiary of CuraGen Corporation, announced today that its proprietary whole genome sequencing technology was used by scientists at Johnson & Johnson Pharmaceutical Research & Development L.L.C. (J&JPRD) to help understand the basis of tuberculosis drug resistance.

20 Dec 2004

Risk of tuberculosis infection doubles within one year of HIV infection

Scientists previously assumed that there was no increase in tuberculosis risk within the first few years of HIV infection. Pam Sonnenberg of the London School of Hygiene and Tropical Medicine and colleagues were therefore surprised by the results of their research on the two infections, which they conducted in South African gold miners.

20 Dec 2004

Study models impact of anthrax vaccine

Rapidly distributing antibiotics to people exposed to anthrax spores during a bioterrorist attack, could by itself, prevent about 70 percent of anthrax infections from occurring, according to researchers from the Johns Hopkins Bloomberg School of Public Health.

16 Dec 2004

Scientists have identified a novel anti-tuberculosis (TB) compound

Scientists at Johnson & Johnson Pharmaceutical Research and Development have identified a novel anti-tuberculosis (TB) compound that works better and faster than the current standard of care in mouse models of TB infection.

14 Dec 2004

Vaccinating mice against Lyme disease could help reduce the risk of transmission of the disease to humans

Vaccinating large populations of white-footed mice against the bacterium that causes Lyme disease could help reduce the risk of transmission of the disease to humans, says a study supported by the National Institute of Allergy and Infectious Diseases (NIAID).

14 Dec 2004

Start today of human tests for a preventive vaccine against the respiratory disease SARS

Powerful research tools that speed up vaccine development have led to the start today of human tests for a preventive vaccine against the respiratory disease SARS. The disease killed hundreds of people around the world before it was brought under control in 2003 with aggressive conventional public health measures.

13 Dec 2004

Targeted screening of high-risk groups for genital herpes may prevent disease transmission

Identifying asymptomatic people with genital herpes infection through targeted screening of high-risk groups may prevent disease transmission. However, widespread screening of pregnant women is unlikely to reduce the occurrence of herpes in newborns, according to an article in the January 1 issue of Clinical Infectious Diseases, now available online.

13 Dec 2004

African health care systems: what went wrong?

The last century witnessed unparalleled improvements in the health indicators of many countries in the African Region, particularly reductions in child mortality.

8 Dec 2004

A new study has found fatty liver disease in nearly one third of American adults in a large urban population sample

The prevalence of the disease varied significantly among ethnic groups. Hispanics had a higher prevalence than whites, while blacks had a lower prevalence than whites.

8 Dec 2004

New clues in understanding why group A streptococci (GAS) has a range of bacterial afflictions in humans

Researchers have unlocked new clues in understanding why group A streptococci (GAS) has a range of bacterial afflictions in humans. One of the keys to this species of bacteria is its production of streptokinase (SK), an enzyme that activates plasminogen, the blood clot-dissolving protein in humans.

6 Dec 2004

New research aims to reduce deaths and ease burden on hospitals

New research by scientists at Australia's Macquarie University will investigate antibiotic resistance genes in humans in an effort to combat worldwide death rates due to infectious diseases and reduce the growing burden on our health system by decreasing patients' length of stay.

6 Dec 2004

Alliance to develop and commercialize fully-human anti-anthrax antibody

MDX-1303 was developed by Medarex using its UltiMAb Human Antibody Development System, and this antibody is currently in preclinical development by Medarex for use against human anthrax infection.

6 Dec 2004

Why our immune system worsens with age

Scientists at the Vaccine and Gene Therapy Institute at Oregon Health & Science University have made a discovery that helps explain why our immune system worsens with age. The work was led by Janko Nikolich-Zugich, M.D., Ph.D., a senior scientist at the VGTI.

2 Dec 2004

Anti-bird flu contingency measures for Hong Kong

Anti-bird flu contingency measures, including a proposal to separate poultry from humans and a series of traffic and logistics measures will be discussed at Hong Kong's Legislative Council's Food Safety and Environmental Hygiene Panel meeting next month.

29 Nov 2004

Oral administration of saline spray may stop spread of influenza, tuberculosis, and SARS

Some individuals exhale many more pathogen-laden droplets than others in the course of ordinary breathing, scientists have found, but oral administration of a safe saline spray every six hours might slash exhalation of germs in this group by an average 72 percent.

29 Nov 2004

Joint collaboration to fight avian influenza

Recognizing the pandemic potential and the threat to public health posed by the Avian Influenza, Health Ministers and senior officials of thirteen countries from Southeast and East Asian countries have pledged to accelerate joint collaboration in fighting the disease.

29 Nov 2004

SARS outbreak unlikely according to World Health Organization

The regional head of the World Health Organization said today that it was possible the region would experience SARS cases this winter, but he doubted the situation would be serious. "I don't think a large outbreak is likely," said Dr Shigeru Omi, Regional Director of WHO's Western Pacific Regional Office.

29 Nov 2004

Infectious Diseases News and Research

Study on first new potential drug for tuberculosis in 40 years

Risk of tuberculosis infection doubles within one year of HIV infection

Study models impact of anthrax vaccine

Scientists have identified a novel anti-tuberculosis (TB) compound

Vaccinating mice against Lyme disease could help reduce the risk of transmission of the disease to humans

Start today of human tests for a preventive vaccine against the respiratory disease SARS

Targeted screening of high-risk groups for genital herpes may prevent disease transmission

African health care systems: what went wrong?

A new study has found fatty liver disease in nearly one third of American adults in a large urban population sample

New clues in understanding why group A streptococci (GAS) has a range of bacterial afflictions in humans

New research aims to reduce deaths and ease burden on hospitals

Alliance to develop and commercialize fully-human anti-anthrax antibody

Why our immune system worsens with age

Anti-bird flu contingency measures for Hong Kong

Oral administration of saline spray may stop spread of influenza, tuberculosis, and SARS

Joint collaboration to fight avian influenza

SARS outbreak unlikely according to World Health Organization

Guatemalan Congress repeals law that restricted access to medicines

Asthma study looks at genetic variation and influence response to microbial exposure

Researchers recommend vaccinating adolescents against whooping cough

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