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Killing of polio workers in Pakistan is major setback for global elimination drive

"The brutal assassination of nine grassroots level health workers in Pakistan, who were involved in a door-to-door immunization campaign in an attempt to secure children from crippling polio, adds an unprecedentedly grave dimension to the ongoing carnage in Pakistan," Sania Nishtar, founder of Heartfile, Heartfile Health Financing, and the recently launched Sania Nishtar Health Fund, writes in an opinion piece in the Huffington Post U.K.'s "Impact" blog.

4 Jan 2013

Pakistan records 306 measles cases in 2012, compared with 64 in 2011, WHO reports

"Measles cases surged in Pakistan in 2012, and hundreds of children died from the disease, an international health body said Tuesday," the Associated Press/CBS News reports. "A spokeswoman for the World Health Organization, Maryam Yunus, said that 306 children died in Pakistan of measles in 2012, compared to 64 the year before," the news agency writes.

4 Jan 2013

Researchers create killer T lymphocytes from iPS cells

Researchers from the RIKEN Research Centre for Allergy and Immunology in Japan report today that they have succeeded for the first time in creating cancer-specific, immune system cells called killer T lymphocytes, from induced pluripotent stem cells (iPS cells).

4 Jan 2013

Fiscal deal political fallout will likely shape future Medicare, entitlement spending battles

News outlets continue to analyze how the fiscal deal will set the table for future deficit debates and when some of the difficult spending issues could again take center stage.

4 Jan 2013

Stanford scientists identify molecular basis for hypertrophic cardiomyopathy

When a young athlete dies unexpectedly on the basketball court or the football field, it's both shocking and tragic. Now Stanford University School of Medicine researchers have, for the first time, identified the molecular basis for a condition called hypertrophic cardiomyopathy that is the most common cause for this type of sudden cardiac death.

4 Jan 2013

Thai health advocates work to protect special provisions on medicines under E.U. free trade agreement

Thailand and the European Union (E.U.) are expected to begin talks on a free trade agreement early this year, and Thai public health advocates have sent a letter to Joao Aguiar Machado, deputy director general for trade at the European Commission, "calling for the bloc to respect global trade rules' special provisions for developing countries," Inter Press Service reports.

4 Jan 2013

Scientists invent scalable method to make polyhydroxylated steroids

Scientists at The Scripps Research Institute (TSRI) have achieved a feat in synthetic chemistry by inventing a scalable method to make complex natural compounds known as "polyhydroxylated steroids." These compounds, used in heart-failure medications and other drugs, have been notoriously problematic to synthesize in the laboratory.

4 Jan 2013

Viewpoints: McConnell says spending cuts are coming; Plea to Kan. governor to rethink insurance exchange

Predictably, the President is already claiming that his tax hike on the "rich" isn't enough. I have news for him: the moment that he and virtually every elected Democrat in Washington signed off on the terms of the current arrangement, it was the last word on taxes.

4 Jan 2013

Workers with low wages more likely to develop hypertension

Workers earning the lowest wages have a higher risk of hypertension than workers with the highest wages, according to new research from UC Davis.

4 Jan 2013

Hobby Lobby won't offer contraception coverage, defying health law and rulings; States face implementation battles

After losing a last-minute appeal to the Supreme Court, craft stores chain Hobby Lobby said it would defy a federal health care mandate requiring employers to provide their workers with insurance that covers emergency contraceptives.

4 Jan 2013

PSCA gene’s rs2294008 variant on T nucleotide may increase risk of bladder cancer

Patients who have inherited a specific common genetic variant develop bladder cancer tumors that strongly express a protein known as prostate stem cell antigen (PSCA), which is also expressed in many pancreatic and prostate tumors, according to research at the National Institutes of Health.

4 Jan 2013

Chromatin regulation not governed by a uniform histone code

In a novel use of gene knockout technology, researchers at the University of California, San Diego School of Medicine tested the same gene inserted into 90 different locations in a yeast chromosome - and discovered that while the inserted gene never altered its surrounding chromatin landscape, differences in that immediate landscape measurably affected gene activity.

4 Jan 2013

Statin therapy affects muscles’ energy production

Up to 75 per cent of patients who take statins to treat elevated cholesterol levels may suffer from muscle pain. Scientists at the Center for Healthy Aging at the University of Copenhagen have now identified a possible mechanism underlying this unfortunate side effect.

4 Jan 2013

New insight into 22q11.2 deletion syndrome

Research out of the George Washington University (GW), published in the journal Proceedings of the National Academy of Sciences (PNAS), reveals another piece of the puzzle in a genetic developmental disorder that causes behavioral diseases such as autism.

4 Jan 2013

Markey practitioner receives Lexington Cancer Foundation grant to continue JSJ program

The University of Kentucky Markey Cancer Center's Jennifer Bradley has received funding from the Lexington Cancer Foundation to continue the Jin Shin Jyutsu program in 2013.

4 Jan 2013

New rat model simulates traumatic or surgical muscle tissue loss in humans

Penetrating soft tissue injuries that may be caused by bullet wounds or motor vehicle accidents, or exposure to explosive devices in military settings, can cause muscle loss resulting in functional disability and cosmetic deformity. Efforts underway to develop tissue engineering solutions to repair and replace damaged and lost muscle will benefit greatly from the availability of robust animal models to test these innovative therapeutic strategies.

4 Jan 2013

Optofluidics allow for new understanding of resistance to antibiotics

It's often difficult to completely eliminate a bacterial infection with antibiotics; part of the population usually manages to survive. We've known about this phenomenon for quite some time, dating back nearly to the discovery of penicillin. For more than 50 years, scientists have believed that the resistant bacteria were individuals that had stopped growing and dividing.

4 Jan 2013

Algorithms designed to find patients with recurrent cancer within databases do not work

In order to study the effectiveness or cost effectiveness of treatments for recurrent cancer, you first have to discover the patients in medical databases who have recurrent cancer. Generally studies do this with billing or treatment codes - certain codes should identify who does and does not have recurrent cancer. A recent study published in the journal Medical Care shows that the commonly used data determinants of recurrent cancer may be misidentifying patients and potentially leading researchers astray.

4 Jan 2013

Calphotin essential in keeping cellular calcium concentration low

All living cells keep their cellular calcium concentration at a very low level. Since a small increase in calcium can affect many critical cellular functions (an elevated calcium concentration over an extended period can induce cell death), powerful cellular mechanisms ensure that calcium concentration quickly returns to its low level.

4 Jan 2013

Mayo Clinic researchers identify new target to improve treatment of pancreatic cancer

Researchers at Mayo Clinic in Florida have identified a new target to improve treatment of pancreatic ductal adenocarcinoma cancer, which accounts for more than 95 percent of pancreatic cancer cases. This fast-growing, often lethal cancer is resistant to conventional chemotherapy.

4 Jan 2013

Research News and Research

Killing of polio workers in Pakistan is major setback for global elimination drive

Pakistan records 306 measles cases in 2012, compared with 64 in 2011, WHO reports

Researchers create killer T lymphocytes from iPS cells

Fiscal deal political fallout will likely shape future Medicare, entitlement spending battles

Stanford scientists identify molecular basis for hypertrophic cardiomyopathy

Thai health advocates work to protect special provisions on medicines under E.U. free trade agreement

Scientists invent scalable method to make polyhydroxylated steroids

Viewpoints: McConnell says spending cuts are coming; Plea to Kan. governor to rethink insurance exchange

Workers with low wages more likely to develop hypertension

Hobby Lobby won't offer contraception coverage, defying health law and rulings; States face implementation battles

PSCA gene’s rs2294008 variant on T nucleotide may increase risk of bladder cancer

Chromatin regulation not governed by a uniform histone code

Statin therapy affects muscles’ energy production

New insight into 22q11.2 deletion syndrome

Markey practitioner receives Lexington Cancer Foundation grant to continue JSJ program

New rat model simulates traumatic or surgical muscle tissue loss in humans

Optofluidics allow for new understanding of resistance to antibiotics

Algorithms designed to find patients with recurrent cancer within databases do not work

Calphotin essential in keeping cellular calcium concentration low

Mayo Clinic researchers identify new target to improve treatment of pancreatic cancer

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