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Juxtapid receives FDA approval for treatment of rare cholesterol disorder

On Dec. 21, the U.S. Food and Drug Administration approved Juxtapid (lomitapide) to reduce low-density lipoprotein (LDL) cholesterol, total cholesterol, apolipoprotein B, and non-high-density lipoprotein (non-HDL) cholesterol in patients with homozygous familial hypercholesterolemia (HoFH). Juxtapid is intended for use in combination with a low fat diet and other lipid-lowering treatments.

27 Dec 2012

Prevalence of obesity and extreme obesity among young U.S. children may have begun to decline

Obesity and extreme obesity in childhood, which are more prevalent among minority and low-income families, have been associated with other cardiovascular risk factors, increased health care costs, and premature death.

26 Dec 2012

Blood transfusion for patients with myocardial infarction associated with increased all-cause mortality

A meta-analysis of 10 studies suggests that receipt of a blood transfusion among patients with myocardial infarction (heart attack) was associated with increased all-cause mortality compared with not receiving a blood transfusion during heart attack, according to a report published Online First by Archives of Internal Medicine, a JAMA Network publication.

25 Dec 2012

Study suggests genetic component in pain response among children

At least two common gene variants are linked to "clinically meaningful" differences in pain scores in children after major surgery, reports a study in the January issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS).

25 Dec 2012

Elevated C-reactive protein linked to psychological distress and depression

Elevated levels of C-reactive protein, a marker of inflammatory disease, appear to be associated with increased risk of psychological distress and depression in the general population of adults in Denmark, according to a report published Online First by Archives of General Psychiatry, a JAMA Network publication.

25 Dec 2012

Children with chronic conditions use more resources at hospitals

Children with chronic conditions increasingly used more resources in a group of children's hospitals compared with patients without a chronic condition, according to a report that analyzed data from 28 U.S. children's hospitals between 2004 and 2009, and is being published Online First by Archives of Pediatrics & Adolescent Medicine, a JAMA Network publication.

25 Dec 2012

Cellular metabolism of immune cells protect against viral infections and tumours

New research demonstrates that the cellular metabolism of certain immune cells is closely linked to their function, which includes protecting against viral infections and the development of tumours.

25 Dec 2012

Sportsmanship minimizes ice hockey injuries

Banning bodychecking in youth ice hockey games may reduce game-related injury rates and increase overall player safety, systematic review findings show.

24 Dec 2012

BRCA testing impact on ovarian cancer prevention revealed

Research shows that women without a confirmed BRCA mutation are choosing to undergo screening or surgery to prevent ovarian cancer, despite little evidence to support their use in this population.

24 Dec 2012

Hair ethyl glucuronide detects even modest drinking

Hair ethyl glucuronide can be reliably used to detect moderate levels of alcohol consumption in the previous 28 days in patients with liver disease, show study results.

24 Dec 2012

Key to at-home geriatric care lies in reliability

Older individuals who live at home but are dependent on healthcare services perceive their care delivery system to be effective when it involves supportive and reliable services, indicate UK study results.

24 Dec 2012

Parkinson’s: an interview with Steve Ford, CEO of Parkinson’s UK

Parkinson’s disease is a neurological condition that is caused when brain cells, that produce the chemical messenger dopamine, start to die.

24 Dec 2012

Parental drinking habits influence those of their children

Adolescents who have memories of their parents drinking alcohol are at an increased risk for starting to drink alcohol earlier than those who do not, research shows.

22 Dec 2012

UV nail lamp use not associated with skin cancer risk

Research shows that artificial ultraviolet (UV) nail lamps do not significantly increase the risk for developing keratinocyte carcinoma.

22 Dec 2012

Comorbidity could alter joint arthroplasty prognosis

The long-term outcome of hip and knee arthroplasty may be significantly influenced by comorbidity, suggest results from a large register-based study of over 96,000 osteoarthritis patients.

22 Dec 2012

Extended steroid treatment fails to reduce pediatric nephrotic relapse

Study findings indicate that extending initial prednisolone treatment durations in patients with pediatric nephrotic syndrome from 3 to 6 months without increasing the overall dose does not reduce the number of relapses.

22 Dec 2012

Study demonstrates safety of using tPA for stroke in community hospital settings

From the moment a stroke occurs, patients must race against the clock to get treatment that can prevent lasting damage. Now, a new study shows the promise – and the challenges – of getting them state-of-the-art treatment safely at their local hospital, saving precious minutes.

21 Dec 2012

Researchers demonstrate significance of two proteins in nerve cell development

The study conducted by Prof. Frank Bradke's team provides indications on brain development and about the causes of diseases of the nervous system. The results have now been published in "Neuron".

21 Dec 2012

A screening tool to evaluate pre-menstrual disorders

Even though there are many women who do not notice any special symptoms, there are some whose pre-menstrual disorders hamper their everyday lives: depressive mood, anxiety, excessive emotional sensitivity, fatigue, lack of concentration, headache, etc.

21 Dec 2012

BCPR, Orexigen partner to accelerate patient enrollment for Contrave obesity Light Study

Blue Chip Patient Recruitment, a division of Blue Chip Marketing Worldwide, a full-service integrated marketing agency, has successfully partnered with Orexigen Therapeutics to accelerate patient enrollment of The Light Study, Orexigen's cardiovascular outcomes trial evaluating Contrave (naltrexone sustained release (SR)/bupropion SR).

21 Dec 2012